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4NY4
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CRYSTAL STRUCTURE OF CYP3A4 IN COMPLEX WITH AN INHIBITOR
Descriptor:Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, (8R)-3,3-difluoro-8-[4-fluoro-3-(pyridin-3-yl)phenyl]-8-(4-methoxy-3-methylphenyl)-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine
Authors:Branden, G., Sjogren, T., Xue, Y.
Deposit date:2013-12-10
Release date:2014-08-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure-based ligand design to overcome CYP inhibition in drug discovery projects.
Drug Discov Today, 19, 2014
4NZ2
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CRYSTAL STRUCTURE OF CYP2C9 IN COMPLEX WITH AN INHIBITOR
Descriptor:Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ...
Authors:Branden, G., Sjogren, T., Xue, Y.
Deposit date:2013-12-11
Release date:2014-08-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-based ligand design to overcome CYP inhibition in drug discovery projects.
Drug Discov Today, 19, 2014
5NJ4
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FROM MACROCRYSTALS TO MICROCRYSTALS: A STRATEGY FOR MEMBRANE PROTEIN SERIAL CRYSTALLOGRAPHY
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein H chain, Reaction center protein L chain, ...
Authors:Dods, R., Baath, P., Branden, G., Neutze, R.
Deposit date:2017-03-28
Release date:2017-08-16
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:From Macrocrystals to Microcrystals: A Strategy for Membrane Protein Serial Crystallography.
Structure, 25, 2017
5O4C
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FROM MACROCRYSTALS TO MICROCRYSTALS: A STRATEGY FOR MEMBRANE PROTEIN SERIAL CRYSTALLOGRAPHY
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein H chain, Reaction center protein L chain, ...
Authors:Dods, R., Baath, P., Branden, G., Neutze, R.
Deposit date:2017-05-28
Release date:2017-08-16
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:From Macrocrystals to Microcrystals: A Strategy for Membrane Protein Serial Crystallography.
Structure, 25, 2017
5O64
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FROM MACROCRYSTALS TO MICROCRYSTALS: A STRATEGY FOR MEMBRANE PROTEIN SERIAL CRYSTALLOGRAPHY
Descriptor:Photosynthetic reaction center cytochrome c subunit, Reaction center protein H chain, Reaction center protein L chain, ...
Authors:Dods, R., Baath, P., Branden, G., Neutze, R.
Deposit date:2017-06-05
Release date:2017-08-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:From Macrocrystals to Microcrystals: A Strategy for Membrane Protein Serial Crystallography.
Structure, 25, 2017
5NDC
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STRUCTURE OF BA3-TYPE CYTOCHROME C OXIDASE FROM THERMUS THERMOPHILUS BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY
Descriptor:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide IIA, ...
Authors:Andersson, R., Safari, C., Dods, R., Nango, E., Tanaka, R., Nakane, T., Tono, K., Joti, Y., Bath, P., Dunevall, E., Bosman, E., Nureki, O., Iwata, S., Neutze, R., Branden, G.
Deposit date:2017-03-08
Release date:2017-08-23
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature.
Sci Rep, 7, 2017
4YYZ
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11B-HYDROXYSTEROID DEHYDROGENASE TYPE I IN COMPLEX WITH INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, N-[(1R,2s,3S,5s,7s)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Authors:Branden, G., Boden, C., Ogg, D.
Deposit date:2015-03-24
Release date:2016-02-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design of pyrozolo-pyrimidines as 11beta-HSD1 inhibitors through optimisation of molecular electrostatic potential.
Medchemcomm, 6, 2016
5JNQ
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MRAY TUNICAMYCIN COMPLEX
Descriptor:Phospho-N-acetylmuramoyl-pentapeptide-transferase, Tunicamycin, PALMITIC ACID, ...
Authors:Johansson, P.
Deposit date:2016-04-30
Release date:2017-01-11
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:MraY-antibiotic complex reveals details of tunicamycin mode of action.
Nat. Chem. Biol., 13, 2017