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6T9E
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BU of 6t9e by Molmil
Crystal structure of a bispecific DutaFab in complex with human PDGF
Descriptor: DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B
Authors:Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
Deposit date:2019-10-28
Release date:2020-12-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
6T9D
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BU of 6t9d by Molmil
Crystal structure of a bispecific DutaFab in complex with human VEGF121
Descriptor: VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A
Authors:Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
Deposit date:2019-10-28
Release date:2020-12-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.905 Å)
Cite:DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
4V7E
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BU of 4v7e by Molmil
Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ...
Authors:Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2013-11-22
Release date:2014-07-09
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
6Z6L
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BU of 6z6l by Molmil
Cryo-EM structure of human CCDC124 bound to 80S ribosomes
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
3J25
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BU of 3j25 by Molmil
Structural basis for TetM-mediated tetracycline resistance
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Tetracycline resistance protein tetM
Authors:Doenhoefer, A, Franckenberg, S, Wickles, S, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2012-08-22
Release date:2012-10-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis for TetM-mediated tetracycline resistance.
Proc.Natl.Acad.Sci.USA, 109, 2012
8RL2
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BU of 8rl2 by Molmil
Human pre-60S - State 5
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Thoms, M, Denk, T, Beckmann, R.
Deposit date:2024-01-02
Release date:2025-01-15
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Highly conserved ribosome biogenesis pathways between human and yeast revealed by the MDN1-NLE1 interaction and NLE1 containing pre-60S subunits.
Nucleic Acids Res., 53, 2025
2IX8
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BU of 2ix8 by Molmil
MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME
Descriptor: ELONGATION FACTOR 3A
Authors:Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
Deposit date:2006-07-07
Release date:2007-07-10
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
8BIP
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BU of 8bip by Molmil
Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R.
Deposit date:2022-11-02
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
8BJQ
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BU of 8bjq by Molmil
Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R.
Deposit date:2022-11-05
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
4V6I
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BU of 4v6i by Molmil
Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ...
Authors:Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
Deposit date:2010-10-12
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
6Q8Y
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BU of 6q8y by Molmil
Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2018-12-16
Release date:2019-03-13
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
6T83
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BU of 6t83 by Molmil
Structure of yeast disome (di-ribosome) stalled on poly(A) tract.
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
Deposit date:2019-10-24
Release date:2019-12-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6T7T
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BU of 6t7t by Molmil
Structure of yeast 80S ribosome stalled on poly(A) tract.
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
Deposit date:2019-10-23
Release date:2019-12-25
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
6TB3
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BU of 6tb3 by Molmil
yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex
Descriptor: 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
Deposit date:2019-10-31
Release date:2020-04-22
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
5JCS
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BU of 5jcs by Molmil
CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E.
Deposit date:2016-04-15
Release date:2016-11-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Nat.Struct.Mol.Biol., 23, 2016
6TMF
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BU of 6tmf by Molmil
Structure of an archaeal ABCE1-bound ribosomal post-splitting complex
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kratzat, H, Becker, T, Tampe, R, Beckmann, R.
Deposit date:2019-12-04
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
5JTE
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BU of 5jte by Molmil
Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N.
Deposit date:2016-05-09
Release date:2016-07-20
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5JU8
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BU of 5ju8 by Molmil
Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N.
Deposit date:2016-05-10
Release date:2016-07-20
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5JPQ
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BU of 5jpq by Molmil
Cryo-EM structure of the 90S pre-ribosome
Descriptor: 18S ribosomal RNA, Bms1, Emg1, ...
Authors:Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R.
Deposit date:2016-05-04
Release date:2016-07-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome.
Cell, 166, 2016
1YSH
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BU of 1ysh by Molmil
Localization and dynamic behavior of ribosomal protein L30e
Descriptor: 40S RIBOSOMAL PROTEIN S13, RNA (101-MER), RNA (28-MER), ...
Authors:Halic, M, Becker, T, Frank, J, Spahn, C.M, Beckmann, R.
Deposit date:2005-02-08
Release date:2005-07-05
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Localization and dynamic behavior of ribosomal protein L30e
Nat.Struct.Mol.Biol., 12, 2005
9QIW
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BU of 9qiw by Molmil
Human pre-60S - State 3
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Thoms, M, Denk, T, Beckmann, R.
Deposit date:2025-03-17
Release date:2025-04-30
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Highly conserved ribosome biogenesis pathways between human and yeast revealed by the MDN1-NLE1 interaction and NLE1 containing pre-60S subunits.
Nucleic Acids Res., 53, 2025
6TNU
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BU of 6tnu by Molmil
Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.
Descriptor: 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
Deposit date:2019-12-10
Release date:2020-04-22
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
4URD
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BU of 4urd by Molmil
Cryo-EM map of Trigger Factor bound to a translating ribosome
Descriptor: TRIGGER FACTOR
Authors:Deeng, J, Chan, K.Y, van der Sluis, E, Bischoff, L, Berninghausen, O, Han, W, Gumbart, J, Schulten, K, Beatrix, B, Beckmann, R.
Deposit date:2014-06-27
Release date:2016-01-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Dynamic Behavior of Trigger Factor on the Ribosome.
J.Mol.Biol., 428, 2016
4V6U
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BU of 4v6u by Molmil
Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ...
Authors:Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N.
Deposit date:2012-08-09
Release date:2014-07-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution.
Nucleic Acids Res., 41, 2013
4V6M
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BU of 4v6m by Molmil
Structure of the ribosome-SecYE complex in the membrane environment
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 16S RIBOSOMAL RNA, ...
Authors:Frauenfeld, J, Gumbart, J, van der Sluis, E.O, Funes, S, Gartmann, M, Beatrix, B, Mielke, T, Berninghausen, O, Becker, T, Schulten, K, Beckmann, R.
Deposit date:2011-02-08
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Cryo-EM structure of the ribosome-SecYE complex in the membrane environment.
Nat.Struct.Mol.Biol., 18, 2011

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