Author results

4ECX
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 300 SEC
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.744 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECY
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 6.0 (NA+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.943 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ECZ
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 6.5 (NA+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.834 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED0
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 6.8 (NA+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED1
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 7.0 (NA+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.806 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED2
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 7.2 (NA+ HEPES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED3
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: AT CRYSTAL AT PH 7.5 (NA+ HEPES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-26
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED6
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 6.7 FOR 15 HR, SIDEWAY TRANSLOCATION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-27
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED7
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: TG CRYSTAL AT PH 7.0 (K+ MES) WITH 1 CA2+ ION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-27
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.717 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4ED8
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE TG CRYSTAL AT PH 7.0, NORMAL TRANSLOCATION
Descriptor:DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Nakamura, T., Zhao, Y., Yang, W.
Deposit date:2012-03-27
Release date:2012-07-11
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
4J9K
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A T AT THE PRIMER 3' END (TA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9L
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A C AT THE PRIMER 3' END (CA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9M
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER AN A AT THE PRIMER 3' END (AA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9N
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A G AT THE PRIMER 3' END (GA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9O
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: PRIMER EXTENSION AFTER A T:G MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*T*AP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9P
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HUMAN DNA POLYMERASE ETA-DNA POSTINSERTION BINARY COMPLEX WITH TA BASE PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9Q
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HUMAN DNA POLYMERASE ETA-DNA POSTINSERTION BINARY COMPLEX WITH TG MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*C*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9R
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HUMAN DNA POLYMERASE ETA-DNA TRANSLOCATED BINARY COMPLEX WITH TG MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9S
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HUMAN DNA POLYMERASE ETA-DNA TRANSLOCATED BINARY COMPLEX: WITH TA BASE PAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*TP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4N7V
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CRYSTAL STRUCTURE OF HUMAN PLK4 CRYPTIC POLO BOX (CPB) IN COMPLEX WITH A CEP152 N-TERMINAL FRAGMENT
Descriptor:Serine/threonine-protein kinase PLK4, Centrosomal protein of 152 kDa
Authors:Park, S.-Y., Park, J.-E., Tian, L., Kim, T.-S., Yang, W., Lee, K.S.
Deposit date:2013-10-16
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4N7Z
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CRYSTAL STRUCTURE OF HUMAN PLK4 CRYPTIC POLO BOX (CPB) IN COMPLEX WITH A CEP192 N-TERMINAL FRAGMENT
Descriptor:Serine/threonine-protein kinase PLK4, Centrosomal protein of 192 kDa
Authors:Park, S.-Y., Park, J.-E., Tian, L., Kim, T.-S., Yang, W., Lee, K.S.
Deposit date:2013-10-16
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4Q8E
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE A PHENANTHRIPLATIN ADDUCTED G
Descriptor:DNA polymerase eta, 5'-D(*CP*AP*TP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3', 5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3', ...
Authors:Gregory, M.T., Yang, W.
Deposit date:2014-04-26
Release date:2014-07-02
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q8F
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HUMAN DNA POLYMERASE ETA EXTENDING PRIMER IMMEDIATELY AFTER A PHENANTHRIPLATIN ADDUCTED G
Descriptor:DNA polymerase eta, 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', ...
Authors:Gregory, M.T., Yang, W.
Deposit date:2014-04-26
Release date:2014-07-02
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WWX
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CRYSTAL STRUCTURE OF THE CORE RAG1/2 RECOMBINASE
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, ZINC ION
Authors:Kim, M.S., Lapkouski, M., Yang, W., Gellert, M.
Deposit date:2014-11-12
Release date:2015-02-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.2001 Å)
Cite:Crystal structure of the V(D)J recombinase RAG1-RAG2.
Nature, 518, 2015
4XVI
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BINARY COMPLEX OF HUMAN POLYMERASE NU AND DNA WITH THE FINGER DOMAIN AJAR
Descriptor:DNA polymerase nu, DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3')
Authors:Lee, Y.-S., Yang, W.
Deposit date:2015-01-27
Release date:2015-03-11
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015