Author results

3OOI
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CRYSTAL STRUCTURE OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE NSD1 SET DOMAIN IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, ZINC ION, ...
Authors:Qiao, Q., Wang, M., Xu, R.M.
Deposit date:2010-08-31
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation
J.Biol.Chem., 286, 2010
3QD7
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CRYSTAL STRUCTURE OF YDAL, A STAND-ALONE SMALL MUTS-RELATED PROTEIN FROM ESCHERICHIA COLI
Descriptor:Uncharacterized protein ydaL
Authors:Gui, W.J., Qu, Q.H., Chen, Y.Y., Wang, M., Zhang, X.E., Bi, L.J., Jiang, T.
Deposit date:2011-01-18
Release date:2011-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of YdaL, a stand-alone small MutS-related protein from Escherichia coli.
J.Struct.Biol., 174, 2011
3QYT
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DIFERRIC BOUND HUMAN SERUM TRANSFERRIN
Descriptor:Serotransferrin, FE (III) ION, CARBONATE ION, ...
Authors:Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
Deposit date:2011-03-03
Release date:2012-03-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
3UA3
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CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5 IN COMPLEX WITH SAH
Descriptor:Protein arginine N-methyltransferase 5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M.
Deposit date:2011-10-20
Release date:2011-12-14
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
3UA4
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CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5
Descriptor:Protein arginine N-methyltransferase 5, GLYCEROL
Authors:Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M.
Deposit date:2011-10-21
Release date:2011-12-14
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
3UYI
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CRYSTAL STRUCTURE OF PERAKINE REDUCTASE, FOUNDER MEMBER OF A NOVEL AKR SUBFAMILY WITH UNIQUE CONFORMATIONAL CHANGES DURING NADPH BINDING
Descriptor:Perakine reductase
Authors:Sun, L., Chen, Y., Rajendran, C., Panjikar, S., Mueller, U., Wang, M., Rosenthal, C., Mindnich, R., Penning, T.M., Stoeckigt, J.
Deposit date:2011-12-06
Release date:2012-02-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
3V0S
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CRYSTAL STRUCTURE OF PERAKINE REDUCTASE, FOUNDER MEMBER OF A NOVEL AKR SUBFAMILY WITH UNIQUE CONFORMATIONAL CHANGES DURING NADPH BINDING
Descriptor:Perakine reductase, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE
Authors:Sun, L., Chen, Y., Rajendran, C., Panjikar, S., Mueller, U., Wang, M., Rosenthal, C., Mindnich, R., Penning, T.M., Stoeckigt, J.
Deposit date:2011-12-08
Release date:2012-02-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
3V0T
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CRYSTAL STRUCTURE OF PERAKINE REDUCTASE, FOUNDER MEMBER OF A NOVEL AKR SUBFAMILY WITH UNIQUE CONFORMATIONAL CHANGES DURING NADPH BINDING
Descriptor:Perakine Reductase, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE
Authors:Sun, L., Chen, Y., Rajendran, C., Panjikar, S., Mueller, U., Wang, M., Rosenthal, C., Mindnich, R., Penning, T.M., Stoeckigt, J.
Deposit date:2011-12-08
Release date:2012-02-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.333 Å)
Cite:Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
3V0U
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CRYSTAL STRUCTURE OF PERAKINE REDUCTASE, FOUNDER MEMBER OF A NOVEL AKR SUBFAMILY WITH UNIQUE CONFORMATIONAL CHANGES DURING NADPH BINDING
Descriptor:Perakine reductase
Authors:Sun, L., Chen, Y., Rajendran, C., Panjikar, S., Mueller, U., Wang, M., Rosenthal, C., Mindnich, R., Penning, T.M., Stoeckigt, J.
Deposit date:2011-12-08
Release date:2012-02-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
3V1S
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SCAFFOLD TAILORING BY A NEWLY DETECTED PICTET-SPENGLERASE AC-TIVITY OF STRICTOSIDINE SYNTHASE (STR1): FROM THE COMMON TRYP-TOLINE SKELETON TO THE RARE PIPERAZINO-INDOLE FRAMEWORK
Descriptor:Strictosidine synthase, 2-(1H-indol-1-yl)ethanamine
Authors:Wu, F., Zhu, H., Sun, L., Rajendran, C., Wang, M., Ren, X., Panjikar, S., Cherkasov, A., Zou, H., Stoeckigt, J.
Deposit date:2011-12-10
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.328 Å)
Cite:Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
J.Am.Chem.Soc., 134, 2012
3VGX
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STRUCTURE OF GP41 T21/CP621-652
Descriptor:Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL
Authors:Yao, X., Waltersperger, S., Wang, M., Cui, S.
Deposit date:2011-08-22
Release date:2012-04-25
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
3VTQ
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NOVEL HIV FUSION INHIBITOR
Descriptor:Envelope glycoprotein gp160, fusion inhibitor MT-Sifuvirtide
Authors:Yao, X., Waltersperger, S., Wang, M., Cui, S.
Deposit date:2012-06-02
Release date:2013-06-26
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal structure of a novel HIV fusion inhibitor
To be Published
4FIU
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THE STRUCTURE OF HEMAGGLUTININ OF H16 SUBTYPE INFLUENZA VIRUS WITH V327G MUTATION
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE
Authors:Lu, X., Shi, Y., Gao, F., Xiao, H., Wang, M., Qi, J., Gao, G.F.
Deposit date:2012-06-11
Release date:2012-11-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
J.Virol., 86, 2012
4H0W
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BISMUTH BOUND HUMAN SERUM TRANSFERRIN
Descriptor:Serotransferrin, FE (III) ION, CARBONATE ION, ...
Authors:Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
Deposit date:2012-09-10
Release date:2012-12-26
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe.
Sci Rep, 2, 2012
4IMB
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STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH 2-(1-METHYL-1H-INDOL-3-YL)ETHANAMINE
Descriptor:Strictosidine synthase, 2-(1-methyl-1H-indol-3-yl)ethanamine
Authors:Stoeckigt, J., Fangrui, W., Wang, M., Rajendran, C.
Deposit date:2013-01-02
Release date:2014-01-29
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Using Strictosidine Synthase to Prepare Novel Alkaloids.
Curr.Med.Chem., 2015
4IYG
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STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH 2-(1H-INDOL-3-YL)-N-METHYLETHANAMINE
Descriptor:Strictosidine synthase, 2-(1H-indol-3-yl)-N-methylethanamine
Authors:Stoeckigt, J., Fangrui, W., Wang, M., Rajendran, C.
Deposit date:2013-01-28
Release date:2014-01-29
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Using Strictosidine Synthase to Prepare Novel Alkaloids.
Curr.Med.Chem., 2015
4J12
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MONOMERIC FC
Descriptor:human Fc fragment, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Ishino, T., Wang, M., Mosyak, L., Tam, A., Duan, W., Svenson, K., Joyce, A., O'Hara, D., Lin, L., Somers, W., Kriz, R.
Deposit date:2013-01-31
Release date:2013-05-01
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics.
J.Biol.Chem., 288, 2013
4PW5
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5HMC-CONTAINING DNA, COMPLEX I
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2
Authors:ZHou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW6
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5HMC-CONTAINING DNA, COMPLEX II
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2
Authors:Zhou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-18
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.789 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4PW7
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STRUCTURE OF UHRF2-SRA IN COMPLEX WITH A 5MC-CONTAINING DNA
Descriptor:E3 ubiquitin-protein ligase UHRF2, 5mC-containing DNA1, 5mC-containing DNA2
Authors:ZHou, T., Xiong, J., Wang, M., Yang, N., Wong, J., Zhu, B., Xu, R.M.
Deposit date:2014-03-19
Release date:2014-05-07
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54, 2014
4RLM
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HEN EGG-WHITE LYSOZYME SOLVED FROM SERIAL CRYSTALLOGRAPHY AT A SYNCHROTRON SOURCE, DATA PROCESSED WITH CRYSTFEL
Descriptor:Lysozyme C
Authors:Botha, S., Nass, K., Barends, T., Kabsch, W., Latz, B., Dworkowski, F., Foucar, L., Panepucci, E., Wang, M., Shoeman, R., Schlichting, I., Doak, R.B.
Deposit date:2014-10-17
Release date:2015-02-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams.
Acta Crystallogr.,Sect.D, 71, 2015
4RLN
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HEN EGG-WHITE LYSOZYME SOLVED FROM SERIAL CRYSTALLOGRAPHY AT A SYNCHROTRON SOURCE, DATA PROCESSED WITH NXDS
Descriptor:Lysozyme C
Authors:Botha, S., Nass, K., Barends, T., Kabsch, W., Latz, B., Dworkowski, F., Foucar, L., Panepucci, E., Wang, M., Shoeman, R., Schlichting, I., Doak, R.B.
Deposit date:2014-10-17
Release date:2015-02-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams.
Acta Crystallogr.,Sect.D, 71, 2015
5BTR
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CRYSTAL STRUCTURE OF SIRT1 IN COMPLEX WITH RESVERATROL AND AN AMC-CONTAINING PEPTIDE
Descriptor:NAD-dependent protein deacetylase sirtuin-1, AMC-containing peptide, ZINC ION, ...
Authors:Cao, D., Wang, M., Qiu, X., Liu, D., Jiang, H., Yang, N., Xu, R.M.
Deposit date:2015-06-03
Release date:2015-07-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Genes Dev., 29, 2015
5CQQ
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CRYSTAL STRUCTURE OF THE DROSOPHILA ZESTE DNA BINDING DOMAIN IN COMPLEX WITH DNA
Descriptor:Regulatory protein zeste, DNA (5'-D(*CP*TP*GP*TP*TP*TP*TP*CP*CP*AP*CP*TP*CP*GP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*CP*GP*AP*GP*TP*GP*GP*AP*AP*AP*AP*CP*AP*G)-3')
Authors:Gao, G.N., Wang, M., Yang, N., Huang, Y., Xu, R.M.
Deposit date:2015-07-22
Release date:2015-11-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of Zeste-DNA Complex Reveals a New Modality of DNA Recognition by Homeodomain-Like Proteins
J.Mol.Biol., 427, 2015
5E5A
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CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:DNA (146-MER), Histone H3.2, Histone H4, ...
Authors:Fang, Q., Chen, P., Wang, M., Fang, J., Yang, N., Li, G., Xu, R.M.
Deposit date:2015-10-08
Release date:2016-02-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.809 Å)
Cite:Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016