Author results

6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges
To Be Published
1EGC
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1EGD
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1EGE
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1IVH
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STRUCTURE OF HUMAN ISOVALERYL-COA DEHYDROGENASE AT 2.6 ANGSTROMS RESOLUTION: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY
Descriptor:ISOVALERYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, COENZYME A PERSULFIDE
Authors:Tiffany, K.A., Roberts, D.L., Wang, M., Paschke, R., Mohsen, A.-W.A., Vockley, J., Kim, J.J.P.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human isovaleryl-CoA dehydrogenase at 2.6 A resolution: structural basis for substrate specificity,.
Biochemistry, 36, 1997
1JQI
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CRYSTAL STRUCTURE OF RAT SHORT CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH ACETOACETYL-COA
Descriptor:short chain acyl-CoA dehydrogenase, ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Battaile, K.P., Molin-Case, J., Paschke, R., Wang, M., Bennett, D., Vockley, J., Kim, J.-J.P.
Deposit date:2001-08-07
Release date:2002-02-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.
J.Biol.Chem., 277, 2002
1LI4
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HUMAN S-ADENOSYLHOMOCYSTEINE HYDROLASE COMPLEXED WITH NEPLANOCIN
Descriptor:S-adenosylhomocysteine hydrolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1,2-DIOL, ...
Authors:Yang, X., Hu, Y., Yin, D.H., Turner, M.A., Wang, M., Borchardt, R.T., Howell, P.L., Kuczera, K., Schowen, R.L.
Deposit date:2002-04-17
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: Transition-state stabilization and the avoidance of abortive reactions
Biochemistry, 42, 2003
1XXO
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X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PYRIDOXINE 5'-PHOSPHATE OXIDASE AT 1.8 A RESOLUTION
Descriptor:hypothetical protein Rv1155
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Garen, C., James, M.N.G., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-07
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase at 1.8 a resolution
To be Published
1Y30
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X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH FLAVIN MONONUCLEOTIDE AT 2.2 A RESOLUTION
Descriptor:hypothetical protein Rv1155, FLAVIN MONONUCLEOTIDE
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Garen, C., James, M.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-23
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005
1YUY
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HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A
Descriptor:RNA-Dependent RNA polymerase, SULFATE ION
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Nicolas, O., Bedard, J., James, M.N.G.
Deposit date:2005-02-14
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
1YV2
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HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A
Descriptor:RNA dependent RNA polymerase, SULFATE ION, GLYCEROL
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Nicolas, O., Bedard, J., James, M.N.G.
Deposit date:2005-02-14
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors
J.Biol.Chem., 280, 2005
1YVX
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HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:RNA dependent RNA polymerase, SULFATE ION, 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Nicolas, O., Bedard, J., James, M.N.G.
Deposit date:2005-02-16
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
1YVZ
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HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:RNA dependent RNA polymerase, SULFATE ION, 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Nicolas, O., Bedard, J., James, M.N.G.
Deposit date:2005-02-16
Release date:2005-03-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
1Z2M
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CRYSTAL STRUCTURE OF ISG15, THE INTERFERON-INDUCED UBIQUITIN CROSS REACTIVE PROTEIN
Descriptor:interferon, alpha-inducible protein (clone IFI-15K), OSMIUM 4+ ION
Authors:Narasimhan, J., Wang, M., Fu, Z., Klein, J.M., Haas, A.L., Kim, J.J.
Deposit date:2005-03-08
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Interferon-induced Ubiquitin-like Protein ISG15.
J.Biol.Chem., 280, 2005
2AQ6
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X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 1.7 A RESOLUTION
Descriptor:PYRIDOXINE 5'-PHOSPHATE OXIDASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Biswal, B.K., Cherney, M.M., Wang, M., Garen, C., James, M.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-08-17
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005
2D3U
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X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:polyprotein, 5-(4-CYANOPHENYL)-3-{[(2-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID
Authors:Biswal, B.K., Wang, M., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Bedard, J., James, M.N.G.
Deposit date:2005-10-02
Release date:2006-08-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition
J.Mol.Biol., 361, 2006
2D3Z
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X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:polyprotein, 5-(4-FLUOROPHENYL)-3-{[(4-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID
Authors:Biswal, B.K., Wang, M., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Bedard, J., James, M.N.G.
Deposit date:2005-10-04
Release date:2006-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition
J.Mol.Biol., 361, 2006
2D41
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X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR
Descriptor:polyprotein, 5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACID
Authors:Biswal, B.K., Wang, M., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bilimoria, D., Bedard, J., James, M.N.G.
Deposit date:2005-10-05
Release date:2006-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition
J.Mol.Biol., 361, 2006
2FHG
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CRYSTAL STRUCTURE OF MYCOBACTERIAL TUBERCULOSIS PROTEASOME
Descriptor:20S proteasome, alpha and beta subunits, proteasome, ...
Authors:Hu, G., Lin, G., Wang, M., Dick, L., Xu, R.M., Nathan, C., Li, H.
Deposit date:2005-12-23
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structure of the Mycobacterium tuberculosis proteasome and mechanism of inhibition by a peptidyl boronate.
Mol.Microbiol., 59, 2006
2MLB
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NMR SOLUTION STRUCTURE OF A COMPUTATIONAL DESIGNED PROTEIN BASED ON TEMPLATE OF HUMAN ERYTHROCYTIC UBIQUITIN
Descriptor:redesigned ubiquitin
Authors:Xiong, P., Wang, M., Zhang, J., Chen, Q., Liu, H.
Deposit date:2014-02-21
Release date:2014-10-29
Last modified:2016-09-21
Method:SOLUTION NMR
Cite:Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
Nat Commun, 5, 2014
2MN4
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NMR SOLUTION STRUCTURE OF A COMPUTATIONAL DESIGNED PROTEIN BASED ON STRUCTURE TEMPLATE 1CY5
Descriptor:Computational designed protein based on structure template 1cy5
Authors:Xiong, P., Wang, M., Zhang, J., Chen, Q., Liu, H.
Deposit date:2014-03-28
Release date:2014-10-29
Last modified:2016-09-21
Method:SOLUTION NMR
Cite:Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
Nat Commun, 5, 2014
3GYR
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STRUCTURE OF PHENOXAZINONE SYNTHASE FROM STREPTOMYCES ANTIBIOTICUS REVEALS A NEW TYPE 2 COPPER CENTER.
Descriptor:Phenoxazinone synthase, COPPER (II) ION, CU-O-CU LINKAGE, ...
Authors:Smith, A.W., Camara-Artigas, A., Wang, M., Francisco, W.A., Allen, J.P.
Deposit date:2009-04-05
Release date:2009-04-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Phenoxazinone Synthase from Streptomyces Antibioticus Reveals a New Type 2 Copper Center.
Biochemistry, 45, 2006
3JUI
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN TRANSLATION INITIATION FACTOR EIF2B EPSILON SUBUNIT
Descriptor:Translation initiation factor eIF-2B subunit epsilon, GLYCEROL
Authors:Wei, J., Xu, H., Zhang, C., Wang, M., Gao, F., Gong, W.
Deposit date:2009-09-15
Release date:2009-10-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit
To be published
3MDD
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CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kim, J.-J.P., Wang, M., Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993
3MDE
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CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kim, J.-J.P., Wang, M., Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993