Author results

4L53
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CRYSTAL STRUCTURE OF (1R,4R)-4-{4-[7-AMINO-2-(1,2,3-BENZOTHIADIAZOL-7-YL)-3-CHLOROFURO[2,3-C]PYRIDIN-4-YL]-1H-PYRAZOL-1-YL}CYCLOHEXAN-1-OL BOUND TO TAK1-TAB1
分子名称:Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, trans-4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]-1H-pyrazol-1-yl}cyclohexanol, ...
著者Wang, J., Hornberger, K.R., Crew, A.P., Jestel, A., Maskos, K., Moertl, M.
登録日2013-06-10
公開日2013-07-03
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics.
Bioorg.Med.Chem.Lett., 23, 2013
5GPH
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SOLUTION STRUCTURE OF THE PIN1-PPIASE (S138A) MUTANT
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Tochio, N., Wang, J., Tate, S.
登録日2016-08-02
公開日2017-08-09
実験手法SOLUTION NMR
主引用文献Not yet determined
To Be Published
6NXF
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CRYSTAL STRUCTURE OF MOUSE REC114 PH DOMAIN IN COMPLEX WITH ANKRD31 C TERMINUS
分子名称:Meiotic recombination protein REC114, Ankyrin repeat domain 31
著者Wang, J., Patel, D.J.
登録日2019-02-08
公開日2019-04-24
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (2.791 Å)
主引用文献REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks.
Mol.Cell, 74, 2019
1PBZ
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DE NOVO DESIGNED PEPTIDE-METALLOPORPHYRIN COMPLEX, SOLUTION STRUCTURE
分子名称:De novo designed cyclic peptide, COPROPORPHYRIN I CONTAINING CO(III)
著者Wang, J., Rosenblatt, M.M., Suslick, K.S.
登録日2003-05-15
公開日2003-12-09
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献De novo designed cyclic-peptide heme complexes
Proc.Natl.Acad.Sci.USA, 100, 2003
1PCK
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AQUIFEX AEOLICUS KDO8PS IN COMPLEX WITH Z-METHYL-PEP
分子名称:2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, CADMIUM ION, ...
著者Wang, J., Xu, X., Grison, C., Petek, S., Coutrot, P., Birck, M., Woodard, R.W., Gatti, D.L.
登録日2003-05-16
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase.
DRUG DES.DISCOVERY, 18, 2003
1PE1
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AQUIFEX AEOLICUS KDO8PS IN COMPLEX WITH CADMIUM AND 2-PGA
分子名称:2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, CADMIUM ION, ...
著者Wang, J., Xu, X., Grison, C., Petek, S., Coutrot, P., Birck, M.R., Woodard, R.W., Gatti, D.L.
登録日2003-05-20
公開日2004-02-03
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structure-Based Design of Novel Inhibitors of 3-Deoxy-D-manno-octulosonate 8-Phosphate Synthase
DRUG DES.DISCOVERY, 18, 2003
2A5J
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CRYSTAL STRUCTURE OF HUMAN RAB2B
分子名称:Ras-related protein Rab-2B, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Dong, A., Wang, J., Shen, Y., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
登録日2005-06-30
公開日2005-07-19
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Crystal structure of human RAB2B
To be Published
2BAZ
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STRUCTURE OF YOSS, A PUTATIVE DUTPASE FROM BACILLUS SUBTILIS
分子名称:hypothetical protein BSU20020
著者Liang, Y.-H., Wang, J., Su, X.-D.
登録日2005-10-16
公開日2006-10-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of YosS, a putative dUTPase from Bacillus subtilis
To be Published
2KC3
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NMR SOLUTION STRUCTURE OF COMPLETE RECEPTOR BINDING DOMAIN OF HUMAN APOLIPOPROTEIN E
分子名称:Apolipoprotein E
著者Wang, J., Sivashanmugam, A.
登録日2008-12-15
公開日2009-04-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A complete receptor binding domain of human apolipoprotein E
To be Published
4MX7
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STRUCTURE OF MOUSE CD1D IN COMPLEX WITH DIOLEOYL-PHOSPHATIDIC ACID
分子名称:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, N-ACETYL-D-GLUCOSAMINE, ...
著者Zajonc, D.M., Wang, J.
登録日2013-09-25
公開日2014-10-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献TBN
To be Published
4RNG
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF SWEET TRANSPORTERS
分子名称:MtN3/saliva family, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SULFATE ION
著者Hu, Q., Wang, J., Yan, C., Yan, N.
登録日2014-10-24
公開日2014-11-19
最終更新日2014-12-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a bacterial homologue of SWEET transporters.
Cell Res., 24, 2014
5KQG
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CO-CRYSTAL STRUCTURE OF LMW-PTP IN COMPLEX WITH 2-(BENZOTHIAZOL-2-YLAMINO)-2-OXO-1-PHENYLETHANESULFONIC ACID
分子名称:Low molecular weight phosphotyrosine protein phosphatase, (1~{S})-2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-1-phenyl-ethanesulfonic acid
著者Wang, J., Zhang, Z.-Y., Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQL
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CO-CRYSTAL STRUCTURE OF LMW-PTP IN COMPLEX WITH 2-OXO-1-PHENYL-2-(PHENYLAMINO)ETHANESULFONIC ACID
分子名称:Low molecular weight phosphotyrosine protein phosphatase, (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid
著者Wang, J., Zhang, Z.-Y., Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQM
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CO-CRYSTAL STRUCTURE OF LMW-PTP IN COMPLEX WITH MES
分子名称:Low molecular weight phosphotyrosine protein phosphatase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
著者Wang, J., Zhang, Z.-Y., Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5KQP
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CRYSTAL STRUCTURE OF APO-FORM LMW-PTP
分子名称:Low molecular weight phosphotyrosine protein phosphatase
著者Wang, J., Zhang, Z.-Y., Yu, Z.-H.
登録日2016-07-06
公開日2016-10-12
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism.
J.Med.Chem., 2016
5V2C
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RE-REFINEMENT OF CRYSTAL STRUCTURE OF PHOTOSYSTEM II COMPLEX
分子名称:Photosystem II protein D1, Photosystem II CP47 reaction center protein, Photosystem II CP43 reaction center protein, ...
著者Wang, J., Wiwczar, J.M., Brudvig, G.W.
登録日2017-03-03
公開日2017-08-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Chlorophyll a with a farnesyl tail in thermophilic cyanobacteria.
Photosyn. Res., 134, 2017
5VCJ
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STRUCTURE OF ALPHA-GALACTOSYLPHYTOSPHINGOSINE BOUND BY CD1D AND IN COMPLEX WITH THE VA14VB8.2 TCR
分子名称:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Chimeric TCR Valpha14/Jalpha18 chain (mouse variable domain, ...
著者Wang, J., Zajonc, D.M.
登録日2017-03-31
公開日2018-04-04
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist.
Org. Biomol. Chem., 17, 2019
3J9B
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ELECTRON CRYO-MICROSCOPY OF AN RNA POLYMERASE
分子名称:Polymerase, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ...
著者Chang, S.H., Sun, D.P., Liang, H.H., Wang, J., Li, J., Guo, L., Wang, X.L., Guan, C.C., Boruah, B.M., Yuan, L.M., Feng, F., Yang, M.R., Wojdyla, J., Wang, J.W., Wang, M.T., Wang, H.W., Liu, Y.F.
登録日2014-12-16
公開日2015-02-18
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution.
Mol.Cell, 2015
4CDQ
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP2
分子名称:VP1, VP2, VP3, ...
著者DeColibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-05
公開日2014-02-12
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDU
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP3
分子名称:VP1, VP2, VP3, ...
著者De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-06
公開日2014-02-12
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP4
分子名称:VP1, VP2, VP3, ...
著者De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-06
公開日2014-02-12
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDX
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP12
分子名称:VP1, VP2, VP3, ...
著者De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-07
公開日2014-02-12
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEW
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR ALD
分子名称:VP1, VP2, VP3, ...
著者De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-12
公開日2014-02-12
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEY
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR NLD
分子名称:VP1, VP2, VP3, ...
著者De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
登録日2013-11-12
公開日2014-02-12
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
5XWY
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF LBUCAS13A-CRRNA BINARY COMPLEX
分子名称:A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER)
著者Zhang, X., Wang, Y., Ma, J., Liu, L., Li, X., Li, Z., You, L., Wang, J., Wang, M.
登録日2017-06-30
公開日2017-09-13
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017