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3DVL
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CRYSTAL STRUCTURE OF FULL LENGTH CIRCADIAN CLOCK PROTEIN KAIC WITH CORRECT GEOMETRY AT PHOSPHORYLATION SITES
Descriptor:Circadian clock protein kinase kaiC, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Pattanayek, R., Egli, M.
Deposit date:2008-07-18
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Full Length Circadian Clock Protein KaiC with Correct Geometry at Phosphorylation Sites
To be Published
3JZM
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE MUTANT T432A OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase kaiC, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-23
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K09
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE MUTANT S431D OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase kaiC, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-24
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0A
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE MUTANT S431A OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase KaiC, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-24
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0C
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE DOUBLE MUTANT S431A/T432E OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase KaiC, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-24
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0E
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE MUTANT T426N OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase KaiC, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-24
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0F
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE DOUBLE MUTANT T426A/T432A OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase KaiC, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Pattanayek, R., Egli, M., Pattanayek, S.
Deposit date:2009-09-24
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3OZ3
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VINYL CARBOCYCLIC LNA
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(UVX)P*AP*CP*GP*C)-3'), (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Seth, P.R., Allerson, C.A., Berdeja, A., Siwkowski, A., Pallan, P.S., Gaus, H., Prakash, T.P., Watt, A.T., Egli, M., Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010
3OZ4
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R-METHYL CARBOCYCLIC LNA
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(URX)P*AP*CP*GP*C)-3')
Authors:Seth, P.R., Allerson, C.A., Berdeja, A., Siwkowski, A., Pallan, P.S., Gaus, H., Prakash, T.P., Watt, A.T., Egli, M., Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010
3OZ5
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S-METHYL CARBOCYCLIC LNA
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(UMX)P*AP*CP*GP*C)-3'), SPERMINE
Authors:Seth, P.R., Allerson, C.A., Berdeja, A., Siwkowski, A., Pallan, P.S., Gaus, H., Prakash, T.P., Watt, A.T., Egli, M., Swayze, E.E.
Deposit date:2010-09-24
Release date:2010-11-24
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA.
J.Am.Chem.Soc., 132, 2010
3S1A
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CRYSTAL STRUCTURE OF THE PHOSPHORYLATION-SITE DOUBLE MUTANT S431E/T432E OF THE KAIC CIRCADIAN CLOCK PROTEIN
Descriptor:Circadian clock protein kinase kaiC, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pattanayek, R., Williams, D.W., Rossi, G., Weigand, S., Mori, T., Johnson, C.H., Stewart, P.L., Egli, M.
Deposit date:2011-05-14
Release date:2011-09-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Combined SAXS/EM Based Models of the S. elongatus Post-Translational Circadian Oscillator and its Interactions with the Output His-Kinase SasA.
Plos One, 6, 2011
3UKB
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(R)-CET-BNA DECAMER STRUCTURE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(RCE)P*AP*CP*GP*C)-3')
Authors:Pallan, P.S., Egli, M.
Deposit date:2011-11-09
Release date:2012-06-20
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.
Chem.Commun.(Camb.), 48, 2012
3UKC
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(S)-CET-BNA DECAMER STRUCTURE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(1TL)P*AP*CP*GP*C)-3')
Authors:Pallan, P.S., Egli, M.
Deposit date:2011-11-09
Release date:2012-06-20
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.
Chem.Commun.(Camb.), 48, 2012
3UKE
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(S)-CMOE-BNA DECAMER STRUCTURE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(CSM)P*AP*CP*GP*C)-3')
Authors:Pallan, P.S., Egli, M.
Deposit date:2011-11-09
Release date:2012-06-20
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs.
Chem.Commun.(Camb.), 48, 2012
3V06
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CRYSTAL STRUCTURE OF S-6'-ME-3'-FLUORO HEXITOL NUCLEIC ACID
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(F5H)P*AP*CP*GP*C)-3'), STRONTIUM ION
Authors:Pallan, P.S., Egli, M.
Deposit date:2011-12-07
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.
Biochemistry, 51, 2012
3V07
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CRYSTAL STRUCTURE OF R-6'-ME-3'-FLUORO HEXITOL NUCLEIC ACID
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(F6H)P*AP*CP*GP*C)-3')
Authors:Pallan, P.S., Egli, M.
Deposit date:2011-12-07
Release date:2012-02-08
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.
Biochemistry, 51, 2012
410D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'), SPERMINE
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
411D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHOXYETHYL RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(T39)P*AP*CP*GP*C)-3')
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
412D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-METHYL-[TRI(OXYETHYL)] RIBONUCLEOSIDE
Descriptor:DNA (5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3'), MAGNESIUM ION
Authors:Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Deposit date:1998-06-30
Release date:1998-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
436D
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THE DICKERSON-DREW B-DNA DODECAMER REVISITED-AT ATOMIC RESOLUTION
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Tereshko, V., Minasov, G., Egli, M.
Deposit date:1998-11-12
Release date:1998-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Dickerson-Drew B-DNA Dodecamer Revisited-At Atomic Resolution
J.Am.Chem.Soc., 121, 1999
437D
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CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING
Descriptor:RNA PSEUDOKNOT, MAGNESIUM ION, SODIUM ION
Authors:Su, L., Chen, L., Egli, M., Berger, J.M., Rich, A.
Deposit date:1998-11-24
Release date:1998-12-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
460D
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A "HYDRAT-ION SPINE" IN A B-DNA MINOR GROOVE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, RUBIDIUM ION
Authors:Tereshko, V., Minasov, G., Egli, M.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A "Hydrat-Ion Spine" in a B-DNA minor groove
J.Am.Chem.Soc., 121, 1999
461D
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A "HYDRAT-ION SPINE" IN A B-DNA MINOR GROOVE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), RUBIDIUM ION, MAGNESIUM ION
Authors:Tereshko, V., Minasov, G., Egli, M.
Deposit date:1999-03-12
Release date:1999-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A "Hydrat-Ion Spine" in a B-DNA minor groove
J.Am.Chem.Soc., 121, 1999
476D
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CALCIUM FORM OF B-DNA UNDECAMER GCGAATTCGCG
Descriptor:5'-D(*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', CALCIUM ION
Authors:Minasov, G., Tereshko, V., Egli, M.
Deposit date:1999-06-25
Release date:1999-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing.
J.Mol.Biol., 291, 1999
477D
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CALCIUM FORM OF THE B-DNA DODECAMER GGCGAATTCGCG
Descriptor:5'-D(*GP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', CALCIUM ION
Authors:Minasov, G., Tereshko, V., Egli, M.
Deposit date:1999-06-25
Release date:1999-07-19
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing.
J.Mol.Biol., 291, 1999