Author results

5FYN
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SUB-TOMOGRAM AVERAGING OF TULA VIRUS GLYCOPROTEIN SPIKE
Descriptor:PUUMALA VIRUS GN GLYCOPROTEIN, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Li, S., Rissanen, I., Zeltina, A., Hepojoki, J., Raghwani, J., Harlos, K., Pybus, O.G., Huiskonen, J.T., Bowden, T.A.
Deposit date:2016-03-08
Release date:2016-06-08
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (15.6 Å)
Cite:A Molecular-Level Account of the Antigenic Hantaviral Surface.
Cell Rep., 15, 2016
5G47
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STRUCTURE OF GC GLYCOPROTEIN FROM SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS IN THE TRIMERIC POSTFUSION CONFORMATION
Descriptor:SFTSV GC, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION
Authors:Halldorsson, S., Behrens, A.J., Harlos, K., Huiskonen, J.T., Elliott, R.M., Crispin, M., Brennan, B., Bowden, T.A.
Deposit date:2016-05-05
Release date:2016-07-06
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of a Phleboviral Envelope Glycoprotein Reveals a Consolidated Model of Membrane Fusion.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HNS
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STRUCTURE OF GLYCOSYLATED NPC1 LUMINAL DOMAIN C
Descriptor:Niemann-Pick C1 protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Zhao, Y., Ren, J., Harlos, K., Stuart, D.I.
Deposit date:2016-01-18
Release date:2016-02-10
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions.
Febs Lett., 590, 2016
5J67
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
5J68
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (5.221 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
5J69
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STRUCTURE OF ASTROTACTIN-2, A CONSERVED VERTEBRATE-SPECIFIC AND PERFORIN-LIKE MEMBRANE PROTEIN INVOLVED IN NEURONAL DEVELOPMENT
Descriptor:Astrotactin-2, N-ACETYL-D-GLUCOSAMINE
Authors:Ni, T., Harlos, K., Gilbert, R.J.C.
Deposit date:2016-04-04
Release date:2016-05-25
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.63 Å)
Cite:Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.
Open Biology, 6, 2016
5MGR
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HUMAN RECEPTOR NKR-P1 IN GLYCOSYLATED FORM, EXTRACELLULAR DOMAIN
Descriptor:Killer cell lectin-like receptor subfamily B member 1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Skalova, T., Blaha, J., Stransky, J., Koval, T., Hasek, J., Yuguang, Z., Harlos, K., Vanek, O., Dohnalek, J.
Deposit date:2016-11-22
Release date:2018-06-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of human NKR-P1:LLT1 receptor complex
To Be Published
5MGS
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HUMAN RECEPTOR NKR-P1 IN DEGLYCOSYLATED FORM, EXTRACELLULAR DOMAIN
Descriptor:Killer cell lectin-like receptor subfamily B member 1, N-ACETYL-D-GLUCOSAMINE
Authors:Skalova, T., Blaha, J., Stransky, J., Koval, T., Hasek, J., Yuguang, Z., Harlos, K., Vanek, O., Dohnalek, J.
Deposit date:2016-11-22
Release date:2018-05-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human NKR-P1:LLT1 receptor complex
To Be Published
5MGT
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COMPLEX OF HUMAN NKR-P1 AND LLT1 IN DEGLYCOSYLATED FORMS
Descriptor:C-type lectin domain family 2 member D, Killer cell lectin-like receptor subfamily B member 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Blaha, J., Skalova, T., Stransky, J., Koval, T., Hasek, J., Yuguang, Z., Harlos, K., Vanek, O., Dohnalek, J.
Deposit date:2016-11-22
Release date:2018-06-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of human NKR-P1:LLT1 receptor complex
To Be Published
5MQW
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HIGH-SPEED FIXED-TARGET SERIAL VIRUS CRYSTALLOGRAPHY
Descriptor:Polyhedrin, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Roedig, P., Ginn, H.M., Pakendorf, T., Sutton, G., Harlos, K., Walter, T.S., Meyer, J., Fischer, P., Duman, R., Vartiainen, I., Reime, B., Warmer, M., Brewster, A.S., Young, I.D., Michels-Clark, T., Sauter, N.K., Sikorsky, M., Nelson, S., Damiani, D.S., Alonso-Mori, R., Ren, J., Fry, E.E., David, C., Stuart, D.I., Wagner, A., Meents, A.
Deposit date:2016-12-21
Release date:2017-06-21
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
5NUZ
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JUNIN VIRUS GP1 GLYCOPROTEIN IN COMPLEX WITH AN ANTIBODY FAB FRAGMENT
Descriptor:eOD01 heavy chain, eOD01 light chain, Pre-glycoprotein polyprotein GP complex, ...
Authors:Zeltina, A., Krumm, S.A., Sahin, M., Struwe, W.B., Harlos, K., Nunberg, J.H., Crispin, M., Pinschewer, D.D., Doores, K.J., Bowden, T.A.
Deposit date:2017-05-03
Release date:2017-06-28
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OPG
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STRUCTURE OF THE HANTAAN VIRUS GN GLYCOPROTEIN ECTODOMAIN
Descriptor:envelope glycoprotein Gn, SULFATE ION, GLYCEROL, ...
Authors:Rissanen, I., Stass, R., Zeltina, A., Li, S., Hepojoki, J., Harlos, K., Gilbert, R.J.C., Huiskonen, J.T., Bowden, T.A.
Deposit date:2017-08-09
Release date:2017-08-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope.
J. Virol., 91, 2017
5OSN
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CRYSTAL STRUCTURE OF BOVINE ENTEROVIRUS 2 DETERMINED WITH SERIAL FEMTOSECOND X-RAY CRYSTALLOGRAPHY
Descriptor:Capsid protein, SPHINGOSINE, POTASSIUM ION, ...
Authors:Roedig, P., Ginn, H.M., Pakendorf, T., Sutton, G., Harlos, K., Walter, T.S., Meyer, J., Fischer, P., Duman, R., Vartiainen, I., Reime, B., Warmer, M., Brewster, A.S., Young, I.D., Michels-Clark, T., Sauter, N.K., Kotecha, A., Kelly, J., Rowlands, D.J., Sikorsky, M., Nelson, S., Damiani, D.S., Alonso-Mori, R., Ren, J., Fry, E.E., David, C., Stuart, D.I., Wagner, A., Meents, A.
Deposit date:2017-08-17
Release date:2017-08-30
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
5ZH2
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-5
Descriptor:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH3
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-6
Descriptor:Lysine-tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH4
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-7
Descriptor:Lysine-tRNA ligase, LYSINE, (3R)-6,8-dihydroxy-3-{[(2S,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZH5
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CRYSTAL STRUCTURE OF PFKRS WITH INHIBITOR CLADO-2
Descriptor:Lysine--tRNA ligase, LYSINE, (3S)-6,8-dihydroxy-3-{[(2R,6S)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, ...
Authors:Babbar, P., Malhotra, N., Sharma, M., Harlos, K., Reddy, D.S., Manickam, Y., Sharma, A.
Deposit date:2018-03-11
Release date:2018-06-27
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
5ZKE
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P212121
Descriptor:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
Authors:Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
Deposit date:2018-03-23
Release date:2019-04-24
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
5ZKF
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PLASMODIUM VIVAX P43 IN SPACE GROUP P21
Descriptor:Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43
Authors:Gupta, S., Sharma, M., Harlos, K., Manickam, Y., Sharma, A.
Deposit date:2018-03-23
Release date:2019-04-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural analysis of aminoacyl-tRNA synthetase-interacting multifunctional proteins from plasmodium species
To Be Published
6F8P
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CRYSTAL STRUCTURE OF GN FROM RIFT VALLEY FEVER VIRUS
Descriptor:Glycoprotein
Authors:Halldorsson, S., Bowden, T.A., Harlos, K.
Deposit date:2017-12-13
Release date:2018-01-31
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Shielding and activation of a viral membrane fusion protein.
Nat Commun, 9, 2018
6FKK
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DROSOPHILA SEMAPHORIN 1B, EXTRACELLULAR DOMAINS 1-2
Descriptor:MIP07328p, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be Published
6FKM
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DROSOPHILA PLEXIN A IN COMPLEX WITH SEMAPHORIN 1B
Descriptor:Plexin A, isoform A, MIP07328p, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be published
6FKN
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DROSOPHILA PLEXIN A IN COMPLEX WITH SEMAPHORIN 1B
Descriptor:Plexin A, isoform A, MIP07328p, ...
Authors:Rozbesky, D., Harlos, K., Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (4.801 Å)
Cite:Structural basis of semaphorin-plexin cis interaction
To Be Published
5FKI
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PSEUDORABIES VIRUS (PRV) NUCLEAR EGRESS COMPLEX PROTEINS FITTED AS A HEXAMERIC LATTICE INTO A SUB-TOMOGRAM AVERAGE DERIVED FROM FOCUSED- ION BEAM MILLED LAMELLAE ELECTRON CRYO-MICROSCOPIC DATA
Descriptor:UL31, UL34 protein, ZINC ION, ...
Authors:Hagen, C., Dent, K.C., Zeev Ben Mordehai, T., Vasishtan, D., Antonin, W., Mettenleiter, T.C., Gruenewald, K.
Deposit date:2015-10-16
Release date:2016-03-16
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights Into Inner Nuclear Membrane Remodelling
Cell Rep., 13, 2015
6J7V
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STRUCTURE OF HRPV6 VP5 FITTED IN THE CRYOEM DENSITY OF THE SPIKE
Descriptor:VP5
Authors:El Omari, K., Li, S., Huiskonen, J.T., Stuart, D.I.
Deposit date:2019-01-18
Release date:2019-03-06
Method:ELECTRON MICROSCOPY (16 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019