Author results

3MHD
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CRYSTAL STRUCTURE OF DCR3
分子名称:Tumor necrosis factor receptor superfamily member 6B
著者Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
登録日2010-04-07
公開日2011-02-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3MI8
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THE STRUCTURE OF TL1A-DCR3 COMPLEX
分子名称:TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM, Tumor necrosis factor receptor superfamily member 6B
著者Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
登録日2010-04-09
公開日2011-02-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.951 Å)
主引用文献Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3OUO
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
分子名称:Nucleoprotein, NITRITE ION
著者Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
登録日2010-09-15
公開日2011-05-25
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3OV9
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STRUCTURE OF THE NUCLEOPROTEIN FROM RIFT VALLEY FEVER VIRUS
分子名称:Nucleoprotein, NITRITE ION, SODIUM ION
著者Ferron, F., Danek, E.I., Li, Z., Luo, D., Wong, Y.H., Coutard, B., Lantez, V., Charrel, R., Canard, B., Walz, T., Lescar, J.
登録日2010-09-16
公開日2011-05-25
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes
Plos Pathog., 7, 2011
3RKZ
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DISCOVERY OF A STABLE MACROCYCLIC O-AMINOBENZAMIDE HSP90 INHIBITOR CAPABLE OF SIGNIFICANTLY DECREASING TUMOR VOLUME IN A MOUSE XENOGRAFT MODEL.
分子名称:Heat shock protein HSP 90-alpha, (5R,6S)-3-(L-alanyl)-5,6,15,15,18-pentamethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-12,8-(metheno)[1,5,9]triazacyclotetradecino[1,2-a]indole-9-carboxamide
著者Zapf, C.W., Bloom, J.D., Li, Z., Dushin, R.G., Nittoli, T., Otteng, M., Nikitenko, A., Golas, J.M., Liu, H., Lucas, J., Boschelli, F., Vogan, E., Olland, A., Johnson, M., Levin, J.I.
登録日2011-04-18
公開日2011-07-13
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.5693 Å)
主引用文献Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model.
Bioorg.Med.Chem.Lett., 21, 2011
3SHB
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CRYSTAL STRUCTURE OF PHD DOMAIN OF UHRF1
分子名称:E3 ubiquitin-protein ligase UHRF1, Histone H3 peptide, ZINC ION
著者Hu, L., Li, Z., Wang, P., Lin, Y., Xu, Y.
登録日2011-06-16
公開日2011-08-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2.
Cell Res., 2011
3V5O
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STRUCTURAL AND MECHANISTIC STUDIES OF CATALYSIS AND SULFA DRUG RESISTANCE IN DIHYDROPTEROATE SYNTHASE
分子名称:Dihydropteroate synthase, SULFATE ION
著者Yun, M., Wu, Y., Li, Z., Zhao, Y., Waddell, M.B., Ferreira, A.M., Lee, R.E., Bashford, D., White, S.W.
登録日2011-12-16
公開日2012-03-14
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3WB9
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CRYSTAL STRUCTURES OF MESO-DIAMINOPIMELATE DEHYDROGENASE FROM SYMBIOBACTERIUM THERMOPHILUM
分子名称:Diaminopimelate dehydrogenase, GLYCEROL
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-05-14
公開日2014-03-26
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum.
Chembiochem, 15, 2014
3WBB
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CRYSTAL STRUCTURES OF MESO-DIAMINOPIMELATE DEHYDROGENASE FROM SYMBIOBACTERIUM THERMOPHILUM
分子名称:Diaminopimelate dehydrogenase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-05-14
公開日2014-03-26
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum.
Chembiochem, 15, 2014
3WBF
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CRYSTAL STRUCTURE OF MESO-DIAMINOPIMELATE DEHYDROGENASE FROM SYMBIOBACTERIUM THERMOPHILUM CO-CRYSTALLIZED WITH NADP+ AND DAP
分子名称:Diaminopimelate dehydrogenase, 2,6-DIAMINOPIMELIC ACID, GLYCEROL, ...
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-05-15
公開日2014-03-26
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum.
Chembiochem, 15, 2014
3WGO
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CRYSTAL STRUCTURE OF Q154L/T173I/R199M/P248S/H249/N276S MUTANT OF MESO-DAPDH FROM CLOSTRIDIUM TETANI E88
分子名称:Meso-diaminopimelate dehydrogenase
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-08-06
公開日2014-08-20
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of Q154L/T173I/R199M/P248S/H249 mutant of meso-dapdh from Clostridium tetani E88
To be Published
3WGQ
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CRYSTAL STRUCTURE OF MESO-DAPDH Q154L/T173I/R199M/P248S/H249N/N276S MUTANT WITH DAP OF FROM CLOSTRIDIUM TETANI E88
分子名称:Meso-diaminopimelate dehydrogenase, 2,6-DIAMINOPIMELIC ACID
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-08-07
公開日2014-08-20
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of meso-dapdh Q154L/T173I/R199M/P248S/H249N/N276S mutant with DAP of from Clostridium tetani E88
To be Published
3WGY
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CRYSTAL STRUCTURE OF MESO-DAPDH Q154L/T173I/R199M/P248S/H249N/N276S MUTANT WITH 4-METHYL-2-OXOVALERATE OF FROM CLOSTRIDIUM TETANI E88
分子名称:Meso-diaminopimelate dehydrogenase, 2-OXO-4-METHYLPENTANOIC ACID
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-08-19
公開日2014-08-20
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of meso-dapdh Q154L/T173I/R199M/P248S/H249N/N276S mutant with 4-methyl-2-oxovalerate of from Clostridium tetani E88
to be published
3WGZ
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CRYSTAL STRUCTURE OF MESO-DAPDH Q154L/T173I/R199M/P248S/H249N/N276S MUTANT WITH D-LEUCINE OF FROM CLOSTRIDIUM TETANI E88
分子名称:Meso-diaminopimelate dehydrogenase, D-LEUCINE
著者Liu, W.D., Li, Z., Huang, C.H., Guo, R.T., Wu, Q.Q., Zhu, D.M.
登録日2013-08-20
公開日2014-08-20
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of meso-dapdh Q154L/T173I/R199M/P248S/H249N/N276S mutant with D-leucine of from Clostridium tetani E88
to be published
4NM6
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CRYSTAL STRUCTURE OF TET2-DNA COMPLEX
分子名称:Methylcytosine dioxygenase TET2, 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', ZINC ION, ...
著者Hu, L., Li, Z., Cheng, J., Rao, Q., Gong, W., Liu, M., Wang, P., Xu, Y.
登録日2013-11-14
公開日2013-12-18
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.026 Å)
主引用文献Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
4YOC
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CRYSTAL STRUCTURE OF HUMAN DNMT1 AND USP7/HAUSP COMPLEX
分子名称:DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
著者Cheng, J., Yang, H., Fang, J., Gong, R., Wang, P., Li, Z., Xu, Y.
登録日2015-03-11
公開日2015-05-27
実験手法X-RAY DIFFRACTION (2.916 Å)
主引用文献Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
5A22
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STRUCTURE OF THE L PROTEIN OF VESICULAR STOMATITIS VIRUS FROM ELECTRON CRYOMICROSCOPY
分子名称:VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION
著者Liang, B., Li, Z., Jenni, S., Rameh, A.A., Morin, B.M., Grant, T., Grigorieff, N., Harrison, S.C., Whelan, S.P.J.
登録日2015-05-06
公開日2015-08-19
最終更新日2019-04-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
5A6E
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CRYO-EM STRUCTURE OF THE SLO2.2 NA-ACTIVATED K CHANNEL
分子名称:S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, ...
著者Hite, R.K., Yuan, P., Li, Z., Hsuing, Y., Walz, T., MacKinnon, R.
登録日2015-06-25
公開日2015-10-14
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5A6F
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CRYO-EM STRUCTURE OF THE SLO2.2 NA-ACTIVATED K CHANNEL
分子名称:GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
著者Hite, R.K., Yuan, P., Li, Z., Hsuing, Y., Walz, T., MacKinnon, R.
登録日2015-06-25
公開日2015-10-14
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5A6G
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CRYO-EM STRUCTURE OF THE SLO2.2 NA-ACTIVATED K CHANNEL
分子名称:S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
著者Hite, R.K., Yuan, P., Li, Z., Hsuing, Y., Walz, T., MacKinnon, R.
登録日2015-06-25
公開日2015-10-14
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5A9V
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STRUCTURE OF APO BIPA
分子名称:GTP-BINDING PROTEIN
著者Kumar, V., Chen, Y., Ero, R., Li, Z., Gao, Y.
登録日2015-07-23
公開日2015-09-02
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A9W
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STRUCTURE OF GDPCP BIPA
分子名称:GTP-BINDING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kumar, V., Chen, Y., Ero, R., Li, Z., Gao, Y.
登録日2015-07-23
公開日2015-08-26
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A9X
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STRUCTURE OF GDP BOUND BIPA
分子名称:GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE
著者Kumar, V., Chen, Y., Ero, R., Li, Z., Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A9Y
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STRUCTURE OF PPGPP BIPA
分子名称:GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE
著者Kumar, V., Chen, Y., Ero, R., Li, Z., Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5C56
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CRYSTAL STRUCTURE OF USP7/HAUSP IN COMPLEX WITH ICP0
分子名称:Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7
著者Cheng, J., Li, Z., Gong, R., Fang, J., Yang, Y., Sun, C., Yang, H., Xu, Y.
登録日2015-06-19
公開日2015-07-08
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.685 Å)
主引用文献Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015