Author results

1EWR
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CRYSTAL STRUCTURE OF TAQ MUTS
Descriptor:DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Obmolova, G., Ban, C., Hsieh, P., Yang, W.
Deposit date:2000-04-26
Release date:2000-10-23
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
1FU1
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CRYSTAL STRUCTURE OF HUMAN XRCC4
Descriptor:DNA REPAIR PROTEIN XRCC4, ACETIC ACID
Authors:Junop, M., Modesti, M., Guarne, A., Gellert, M., Yang, W.
Deposit date:2000-09-13
Release date:2000-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Xrcc4 DNA repair protein and implications for end joining.
EMBO J., 19, 2000
1FW6
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CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX
Descriptor:5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3', DNA MISMATCH REPAIR PROTEIN MUTS, ...
Authors:Junop, M.S., Obmolova, G., Rausch, K., Hsieh, P., Yang, W.
Deposit date:2000-09-21
Release date:2001-02-19
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair.
Mol.Cell, 7, 2001
1H7S
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N-TERMINAL 40KDA FRAGMENT OF HUMAN PMS2
Descriptor:PMS1 PROTEIN HOMOLOG 2
Authors:Guarne, A., Junop, M.S., Yang, W.
Deposit date:2001-07-10
Release date:2001-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase
Embo J., 20, 2001
1H7U
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HPMS2-ATPGS
Descriptor:MISMATCH REPAIR ENDONUCLEASE PMS2, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Guarne, A., Junop, M.S., Yang, W.
Deposit date:2001-07-10
Release date:2001-11-27
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase
Embo J., 20, 2001
1HU0
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CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX
Descriptor:5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE 1, ...
Authors:Fromme, J.C., Bruner, S.D., Yang, W., Karplus, M., Verdine, G.L.
Deposit date:2001-01-03
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Product-Assisted Catalysis in base-excision DNA Repair
Nat.Struct.Biol., 10, 2003
1JX4
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CRYSTAL STRUCTURE OF A Y-FAMILY DNA POLYMERASE IN A TERNARY COMPLEX WITH DNA SUBSTRATES AND AN INCOMING NUCLEOTIDE
Descriptor:5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', 5'-D(*T*TP*CP*AP*TP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase IV (family Y), ...
Authors:Ling, H., Boudsocq, F., Woodgate, R., Yang, W.
Deposit date:2001-09-05
Release date:2001-10-05
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication.
Cell(Cambridge,Mass.), 107, 2001
1JXL
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CRYSTAL STRUCTURE OF A Y-FAMILY DNA POLYMERASE IN A TERNARY COMPLEX WITH DNA SUBSTRATES AND AN INCOMING NUCLEOTIDE
Descriptor:5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3', 5'-D(*T*TP*CP*GP*AP*AP*(BRU)P*CP*CP*TP*(BRU)P*CP*CP*CP*CP*C)-3', DNA polymerase IV (family Y), ...
Authors:Ling, H., Boudsocq, F., Woodgate, R., Yang, W.
Deposit date:2001-09-07
Release date:2001-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication.
Cell(Cambridge,Mass.), 107, 2001
1K6Y
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CRYSTAL STRUCTURE OF A TWO-DOMAIN FRAGMENT OF HIV-1 INTEGRASE
Descriptor:Integrase, ZINC ION, POTASSIUM ION, ...
Authors:Wang, J., Ling, H., Yang, W., Craigie, R.
Deposit date:2001-10-17
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.
EMBO J., 20, 2001
1K99
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SOLUTION STRUCTURE OF THE FIRST HMG BOX IN HUMAN UPSTREAM BINDING FACTOR
Descriptor:Upstream binding factor 1
Authors:Xu, Y., Yang, W., Wu, J., Shi, Y.
Deposit date:2001-10-28
Release date:2001-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first HMG box domain in human upstream binding factor.
Biochemistry, 41, 2002
1LRR
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CRYSTAL STRUCTURE OF E. COLI SEQA COMPLEXED WITH HEMIMETHYLATED DNA
Descriptor:5'-D(*CP*AP*CP*CP*GP*AP*TP*CP*GP*AP*CP*T)-3', 5'-D(*AP*GP*TP*CP*GP*(6MA)P*TP*CP*GP*GP*TP*G)-3', SeqA protein
Authors:Guarne, A., Zhao, Q., Guirlando, R., Yang, W.
Deposit date:2002-05-15
Release date:2002-12-11
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex
NAT.STRUCT.BIOL., 9, 2002
1LWV
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BOROHYDRIDE-TRAPPED HOGG1 INTERMEDIATE STRUCTURE CO-CRYSTALLIZED WITH 8-AMINOGUANINE
Descriptor:5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE, ...
Authors:Fromme, J.C., Bruner, S.D., Yang, W., Karplus, M., Verdine, G.L.
Deposit date:2002-06-03
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LWW
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BOROHYDRIDE-TRAPPED HOGG1 INTERMEDIATE STRUCTURE CO-CRYSTALLIZED WITH 8-BROMOGUANINE
Descriptor:5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE, ...
Authors:Fromme, J.C., Bruner, S.D., Yang, W., Karplus, M., Verdine, G.L.
Deposit date:2002-06-03
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LWY
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HOGG1 BOROHYDRIDE-TRAPPED INTERMEDIATE WITHOUT 8-OXOGUANINE
Descriptor:5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE
Authors:Fromme, J.C., Bruner, S.D., Yang, W., Karplus, M., Verdine, G.L.
Deposit date:2002-06-03
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10, 2003
1LZX
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RAT NEURONAL NOS HEME DOMAIN WITH NG-HYDROXY-L-ARGININE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1LZZ
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RAT NEURONAL NOS HEME DOMAIN WITH N-ISOPROPYL-N'-HYDROXYGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1M00
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RAT NEURONAL NOS HEME DOMAIN WITH N-BUTYL-N'-HYDROXYGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1NHH
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL PROTEIN (LN40) COMPLEX WITH ADPNP AND ONE RUBIDIUM
Descriptor:DNA mismatch repair protein mutL, MAGNESIUM ION, RUBIDIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
1NHI
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL (LN40) COMPLEX WITH ADPNP AND ONE POTASSIUM
Descriptor:DNA mismatch repair protein mutL, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
1NHJ
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CRYSTAL STRUCTURE OF N-TERMINAL 40KD MUTL/A100P MUTANT PROTEIN COMPLEX WITH ADPNP AND ONE SODIUM
Descriptor:DNA mismatch repair protein mutL, SODIUM ION, MAGNESIUM ION, ...
Authors:Hu, X., Machius, M., Yang, W.
Deposit date:2002-12-19
Release date:2003-06-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Monovalent cation dependence and preference of GHKL ATPases and kinases
FEBS Lett., 544, 2003
1NNE
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CRYSTAL STRUCTURE OF THE MUTS-ADPBEF3-DNA COMPLEX
Descriptor:5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(P*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3', DNA Mismatch Repair protein MutS, ...
Authors:Alani, E., Lee, J.Y., Schofield, M.J., Kijas, A.W., Hsieh, P., Yang, W.
Deposit date:2003-01-13
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repair
J.Biol.Chem., 278, 2003
1Q2O
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE N368D MUTANT HEME DOMAIN DIMER WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRAMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-07-25
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1RYR
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REPLICATION OF A CIS-SYN THYMINE DIMER AT ATOMIC RESOLUTION
Descriptor:5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', 5'-D(*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase IV, ...
Authors:Ling, H., Boudsocq, F., Plosky, B., Woodgate, R., Yang, W.
Deposit date:2003-12-22
Release date:2004-02-10
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Replication of a Cis-Syn Thymine Dimer at Atomic Resolution
Nature, 424, 2003
1RYS
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REPLICATION OF A CIS-SYN THYMINE DIMER AT ATOMIC RESOLUTION
Descriptor:5'-D(*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*A)-3', 5'-D(*TP*CP*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase IV, ...
Authors:Ling, H., Boudsocq, F., Plosky, B., Woodgate, R., Yang, W.
Deposit date:2003-12-22
Release date:2004-02-10
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Replication of a Cis-Syn Thymine Dimer at Atomic Resolution
Nature, 424, 2003
1S0M
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CRYSTAL STRUCTURE OF A BENZO[A]PYRENE DIOL EPOXIDE ADDUCT IN A TERNARY COMPLEX WITH A DNA POLYMERASE
Descriptor:5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', 5'-D(P*AP*TP*AP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*CP*A)-3', DNA polymerase IV, ...
Authors:Ling, H., Sayer, J.M., Boudsocq, F., Plosky, B.S., Woodgate, R., Yang, W.
Deposit date:2003-12-31
Release date:2004-03-30
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.
Proc.Natl.Acad.Sci.USA, 101, 2004