Author results

5XET
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE BOUND BY METHIONYL-ADENYLATE (MET-AMP)
Descriptor:Methionine--tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, 1,2-ETHANEDIOL, ...
Authors:Wang, W., Qin, B., Wojdyla, J.A., Wang, M., Gao, X., Cui, S.
Deposit date:2017-04-06
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.
IUCrJ, 5, 2018
5XGQ
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CRYSTAL STRUCTURE OF APO FORM (FREE-STATE) MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE
Descriptor:Methionine-tRNA ligase
Authors:Wang, W., Wang, M., Wojdyla, J.A., Cui, S.
Deposit date:2017-04-15
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
IUCrJ, 5, 2018
5Z3W
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MALATE DEHYDROGENASE BINDS SILVER AT C113
Descriptor:Malate dehydrogenase, SILVER ION
Authors:Wang, H., Wang, M., Sun, H.
Deposit date:2018-01-09
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of silver-bound malate dehydrogenase
To Be Published
5ZCJ
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CRYSTAL STRUCTURE OF COMPLEX
Descriptor:Tudor-interacting repair regulator protein, TP53-binding protein 1
Authors:Wang, J., Yuan, Z., Cui, Y., Xie, R., Wang, M., Ma, Y., Yu, X., Liu, X.
Deposit date:2018-02-17
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal structure of complex
To Be Published
6IO4
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-29
Release date:2019-07-03
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IO6
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A AT NON-CATALYTIC SITE
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-29
Release date:2019-07-03
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IOJ
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GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A (APO-FORM)
Descriptor:Glyceraldehyde-3-phosphate dehydrogenase A
Authors:Wang, H., Sun, H., Wang, M.
Deposit date:2018-10-30
Release date:2019-07-03
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
4WAB
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CRYSTAL STRUCTURE OF MPGES1 SOLVED BY NATIVE-SAD PHASING
Descriptor:Prostaglandin E synthase,Leukotriene C4 synthase, GLUTATHIONE, 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide
Authors:Weinert, T., Li, D., Howe, N., Caffrey, M., Wang, M.
Deposit date:2014-08-29
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
6I59
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LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
3ZJ6
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CRYSTAL OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH INHIBITOR
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION, (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol
Authors:Xia, L., Lin, H., Panjikar, S., Ruppert, M., Castiglia, A., Rajendran, C., Wang, M., Schuebel, H., Warzecha, H., Jaeger, V., Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-01-29
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
4ATD
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CRYSTAL STRUCTURE OF NATIVE RAUCAFFRICINE GLUCOSIDASE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-05
Release date:2013-01-16
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4ATL
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CRYSTAL STRUCTURE OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH GLUCOSE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, BETA-D-GLUCOSE
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-08
Release date:2013-01-30
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4R8T
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STRUCTURE OF JEV PROTEASE
Descriptor:Serine protease subunit NS2B, NS3, CHLORIDE ION
Authors:Nair, D.T., Weinert, T., Wang, M., Olieric, V.
Deposit date:2014-09-03
Release date:2014-12-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.133 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4R8U
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S-SAD STRUCTURE OF DINB-DNA COMPLEX
Descriptor:DNA polymerase IV, DNA, MAGNESIUM ION, ...
Authors:Kottur, J., Nair, D.T., Weinert, T., Oligeric, V., Wang, M.
Deposit date:2014-09-03
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
4WAU
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CRYSTAL STRUCTURE OF CENP-M SOLVED BY NATIVE-SAD PHASING
Descriptor:Centromere protein M
Authors:Weinert, T., Basilico, F., Cecatiello, V., Pasqualato, S., Wang, M.
Deposit date:2014-09-01
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WBQ
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CRYSTAL STRUCTURE OF THE EXONUCLEASE DOMAIN OF QIP (QDE-2 INTERACTING PROTEIN) SOLVED BY NATIVE-SAD PHASING.
Descriptor:QDE-2-interacting protein, CALCIUM ION
Authors:Boland, A., Weinert, T., Weichenrieder, O., Wang, M.
Deposit date:2014-09-03
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
5DWK
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DIACYLGLYCEROL KINASE SOLVED BY MULTI CRYSTAL MULTI ORIENTATION NATIVE SAD
Descriptor:Diacylglycerol kinase, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Weinert, T., Olieric, V., Finke, A.D., Li, D., Caffrey, M., Wang, M.
Deposit date:2015-09-22
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Data-collection strategy for challenging native SAD phasing.
Acta Crystallogr D Struct Biol, 72, 2016
5FQ5
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CRYSTAL STRUCTURE OF CAS9-SGRNA-DNA COMPLEX SOLVED BY NATIVE SAD PHASING
Descriptor:SGRNA, CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, TARGET DNA STRAND PROXIMAL FRAGMENT, ...
Authors:Olieric, V., Weinert, T., Finke, A., Anders, C., Jinek, M., Wang, M.
Deposit date:2015-12-07
Release date:2016-03-23
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.136 Å)
Cite:Data-Collection Strategy for Challenging Native Sad Phasing.
Acta Crystallogr.,Sect.D, 72, 2016
5N6H
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6L
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT C387A MUTANT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6M
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM P. AERUGINOSA
Descriptor:Apolipoprotein N-acyltransferase, GLYCEROL, CITRATE ANION, ...
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5OON
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STRUCTURE OF UNDECAPRENYL-PYROPHOSPHATE PHOSPHATASE, BACA
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Warshamanage, R., Wang, M., Howe, N., Ghachi, M.E.I., Weichert, D., Kerff, F., Stansfeld, P., Touze, T., Caffrey, M.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis.
Nat Commun, 9, 2018
1KVK
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THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1Y0H
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STRUCTURE OF RV0793 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:hypothetical protein Rv0793, ACETATE ION
Authors:Lemieux, M.J., Ference, C., Cherney, M.M., Wang, M., Garen, C., James, M.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-15
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis
J.STRUCT.FUNCT.GENOM., 6, 2005