Author results

6GWM
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SOLUTION STRUCTURE OF RAT RIP2 CASPASE RECRUITMENT DOMAIN
Descriptor:Receptor-interacting serine/threonine-protein kinase 2
Authors:Mineev, K.S., Goncharuk, S.A., Artemieva, L.E., Arseniev, A.S.
Deposit date:2018-06-25
Release date:2018-10-31
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:CARD domain of rat RIP2 kinase: Refolding, solution structure, pH-dependent behavior and protein-protein interactions.
PLoS ONE, 13, 2018
6HJ7
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THE NMR STRUCTURE OF NRADD DEATH DOMAIN
Descriptor:Death domain-containing membrane protein NRADD
Authors:Nadezhdin, K.D., Mineev, K.S., Goncharuk, S.A., Arseniev, A.S.
Deposit date:2018-09-01
Release date:2019-05-08
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:NMR structure of a full-length single-pass membrane protein NRADD.
Proteins, 87, 2019
6RRL
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SOLUTION NMR STRUCTURE OF THE PEPTIDE 3967 FROM MEDICINAL LEECH HIRUDO MEDICINALIS IN DODECYLPHOSPHOCHOLINE MICELLES
Descriptor:peptide 3967
Authors:Nadezhdin, K.D., Grafskaia, E.N., Arseniev, A.S., Lazarev, V.N.
Deposit date:2019-05-20
Release date:2019-07-24
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
6RRO
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SOLUTION NMR STRUCTURE OF THE PEPTIDE 536_2 FROM MEDICINAL LEECH HIRUDO MEDICINALIS IN DODECYLPHOSPHOCHOLINE MICELLES
Descriptor:peptide 536_2
Authors:Nadezhdin, K.D., Grafskaia, E.N., Arseniev, A.S., Lazarev, V.N.
Deposit date:2019-05-20
Release date:2019-07-24
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
6RSM
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SOLUTION NMR STRUCTURE OF THE PEPTIDE 12530 FROM MEDICINAL LEECH HIRUDO MEDICINALIS IN DODECYLPHOSPHOCHOLINE MICELLES
Descriptor:peptide 12530
Authors:Talyzina, I.A., Nadezhdin, K.D., Grafskaia, E.N., Arseniev, A.S., Lazarev, V.N.
Deposit date:2019-05-21
Release date:2019-07-24
Method:SOLUTION NMR
Cite:Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
2KGU
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SPATIAL STRUCTURE OF PUROTOXIN-1 IN WATER
Descriptor:Purotoxin-1
Authors:Nadezhdin, K., Vassilevski, A., Arseniev, A., Grishin, E., Pluzhnikov, K., Korolkova, Y.
Deposit date:2009-03-20
Release date:2010-03-31
Last modified:2019-05-15
Method:SOLUTION NMR
Cite:Novel peptide from spider venom inhibits P2X3 receptors and inflammatory pain.
Ann Neurol, 67, 2010
2LOH
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DIMERIC STRUCTURE OF TRANSMEMBRANE DOMAIN OF AMYLOID PRECURSOR PROTEIN IN MICELLAR ENVIRONMENT
Descriptor:P3(42)
Authors:Nadezhdin, K., Bocharov, E., Bocharova, O., Arseniev, A.
Deposit date:2012-01-24
Release date:2012-05-23
Last modified:2012-07-11
Method:SOLUTION NMR
Cite:Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment.
Febs Lett., 586, 2012
2LZO
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SPATIAL STRUCTURE OF PI-ANMTX UGR 9A-1
Descriptor:UGTX
Authors:Mineev, K., Arseniev, A.
Deposit date:2012-10-08
Release date:2013-07-03
Last modified:2017-02-01
Method:SOLUTION NMR
Cite:Sea Anemone Peptide with Uncommon beta-Hairpin Structure Inhibits Acid-sensing Ion Channel 3 (ASIC3) and Reveals Analgesic Activity.
J.Biol.Chem., 288, 2013
2MET
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NMR SPATIAL STRUCTURE OF THE TRIMERIC MUTANT TM DOMAIN OF VEGFR2 RECEPTOR.
Descriptor:Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S., Arseniev, A.A., Shulepko, M., Lyukmanova, E.N., Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
2MIC
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NMR STRUCTURE OF P75 TRANSMEMBRANE DOMAIN IN DPC MICELLES
Descriptor:Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K., Arseniev, A., Goncharuk, S., Mineev, K.
Deposit date:2013-12-12
Release date:2014-12-24
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MJO
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NMR STRUCTURE OF P75 TRANSMEMBRANE DOMAIN C257A MUTANT IN DPC MICELLES
Descriptor:Tumor necrosis factor receptor superfamily member 16
Authors:Nadezhdin, K., Arseniev, A., Goncharuk, S., Mineev, K.
Deposit date:2014-01-15
Release date:2015-01-28
Last modified:2017-09-06
Method:SOLUTION NMR
Cite:Structural Basis of p75 Transmembrane Domain Dimerization.
J. Biol. Chem., 291, 2016
2MZF
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PUROTOXIN-2 NMR STRUCTURE IN WATER
Descriptor:Purotoxin-2
Authors:Nadezhdin, K., Vassilevski, A., Oparin, P., Grishin, E., Arseniev, A.
Deposit date:2015-02-12
Release date:2016-04-13
Last modified:2019-04-17
Method:SOLUTION NMR
Cite:Structure of purotoxin-2 from wolf spider: modular design and membrane-assisted mode of action in arachnid toxins.
Biochem. J., 473, 2016
2MZG
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PUROTOXIN-2 NMR STRUCTURE IN DPC MICELLES
Descriptor:Purotoxin-2
Authors:Nadezhdin, K., Oparin, P., Vassilevski, A., Grishin, E., Arseniev, A.
Deposit date:2015-02-12
Release date:2016-04-13
Last modified:2019-04-17
Method:SOLUTION NMR
Cite:Structure of purotoxin-2 from wolf spider: modular design and membrane-assisted mode of action in arachnid toxins.
Biochem. J., 473, 2016
2N2A
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SPATIAL STRUCTURE OF HER2/ERBB2 DIMERIC TRANSMEMBRANE DOMAIN IN THE PRESENCE OF CYTOPLASMIC JUXTAMEMBRANE DOMAINS
Descriptor:Receptor tyrosine-protein kinase erbB-2
Authors:Bragin, P.E., Mineev, K.S., Bocharov, E., Bocharova, O., Arseniev, A.
Deposit date:2015-05-05
Release date:2016-02-24
Last modified:2017-03-22
Method:SOLUTION NMR
Cite:HER2 Transmembrane Domain Dimerization Coupled with Self-Association of Membrane-Embedded Cytoplasmic Juxtamembrane Regions.
J.Mol.Biol., 428, 2016
2N5S
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SPATIAL STRUCTURE OF EGFR TRANSMEMBRANE AND JUXTAMEMBRANE DOMAINS IN DPC MICELLES
Descriptor:Epidermal growth factor receptor
Authors:Mineev, K., Bocharov, E., Bocharova, O., Arseniev, A.
Deposit date:2015-07-27
Release date:2015-10-14
Last modified:2015-11-11
Method:SOLUTION NMR
Cite:The Membrane Mimetic Affects the Spatial Structure and Mobility of EGFR Transmembrane and Juxtamembrane Domains.
Biochemistry, 54, 2015
2N85
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NMR STRUCTURE OF OTTX1A - AMP IN DPC MICELLES
Descriptor:Spiderine-1a
Authors:Nadezhdin, K., Romanovskaya, D., Sachkova, M., Vassilevski, A., Grishin, E., Kovalchuk, S., Arseniev, A.
Deposit date:2015-10-05
Release date:2016-10-05
Last modified:2019-04-17
Method:SOLUTION NMR
Cite:Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment.
Protein Sci., 26, 2017
2N86
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NMR STRUCTURE OF OTTX1A - ICK
Descriptor:Spiderine-1a
Authors:Nadezhdin, K., Romanovskaya, D., Sachkova, M., Vassilevski, A., Grishin, E., Kovalchuk, S., Arseniev, A.
Deposit date:2015-10-05
Release date:2016-10-19
Last modified:2019-04-17
Method:SOLUTION NMR
Cite:Modular toxin from the lynx spider Oxyopes takobius: Structure of spiderine domains in solution and membrane-mimicking environment.
Protein Sci., 26, 2017
5LV6
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N-TERMINAL MOTIF DIMERIZATION OF EGFR TRANSMEMBRANE DOMAIN IN BICELLAR ENVIRONMENT
Descriptor:Epidermal growth factor receptor
Authors:Bragin, P., Bocharov, E., Mineev, K., Bocharova, O., Arseniev, A.
Deposit date:2016-09-12
Release date:2017-04-05
Method:SOLUTION NMR
Cite:The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment.
Biochemistry, 56, 2017
5LUE
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MINOR FORM OF THE RECOMBINANT CYTOTOXIN-1 FROM N. OXIANA
Descriptor:VC-1=CYTOTOXIN
Authors:Dubovskii, P.V., Dubinnyi, M.A., Shulepko, M.A., Lyukmanova, E.N., Dolgikh, D.A., Kirpichnikov, M.P., Efremov, R.G.
Deposit date:2016-09-08
Release date:2017-09-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
2M1F
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NMR STRUCTURE OF ANTIAMOEBIN I (PEPTAIBOL ANTIBIOTIC) BOUND TO DMPC/DHPC BICELLES
Descriptor:Antiamoebin I
Authors:Shenkarev, Z.O., Paramonov, A.S., Gizatullina, A.K.
Deposit date:2012-11-27
Release date:2012-12-12
Last modified:2013-10-02
Method:SOLUTION NMR
Cite:Peptaibol antiamoebin I: spatial structure, backbone dynamics, interaction with bicelles and lipid-protein nanodiscs, and pore formation in context of barrel-stave model.
Chem.Biodivers., 10, 2013
2MQU
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SPATIAL STRUCTURE OF HM-3, A MEMBRANE-ACTIVE SPIDER TOXIN AFFECTING SODIUM CHANNELS
Descriptor:Neurotoxin Hm-3
Authors:Myshkin, M.Y., Shenkarev, Z.O., Paramonov, A.S., Berkut, A.A., Grishin, E.V., Vassilevski, A.A.
Deposit date:2014-06-27
Release date:2014-11-05
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae.
J. Biol. Chem., 290, 2015
5NAM
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NMR STRUCTURE OF TLR4 TRANSMEMBRANE DOMAIN (624-670) IN DMPG/DHPC BICELLES
Descriptor:Toll-like receptor 4
Authors:Mineev, K.S., Goncharuk, S.A., Goncharuk, M.V., Arseniev, A.S.
Deposit date:2017-02-28
Release date:2017-09-06
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
5NAO
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NMR STRUCTURE OF TLR4 TRANSMEMBRANE DOMAIN (624-657) IN DPC MICELLES
Descriptor:Toll-like receptor 4
Authors:Mineev, K.S., Goncharuk, S.A., Goncharuk, M.V., Arseniev, A.S.
Deposit date:2017-02-28
Release date:2018-03-21
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism.
Sci Rep, 7, 2017
2LG4
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3D SOLUTION STRUCTURE OF ANTIMICROBIAL PEPTIDE AURELIN
Descriptor:Aurelin
Authors:Shenkarev, Z., Altukhov, D.
Deposit date:2011-07-20
Release date:2012-07-25
Last modified:2013-10-02
Method:SOLUTION NMR
Cite:Recombinant expression and solution structure of antimicrobial peptide aurelin from jellyfish Aurelia aurita.
Biochem.Biophys.Res.Commun., 429, 2012
2LJ7
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3D SOLUTION STRUCTURE OF PLANT DEFENSIN LC-DEF
Descriptor:Defensin Lc-def
Authors:Shenkarev, Z., Mineev, K., Gizatullina, A.
Deposit date:2011-09-07
Release date:2012-09-12
Last modified:2015-10-14
Method:SOLUTION NMR
Cite:Heterologous expression and solution structure of defensin from lentil Lens culinaris.
Biochem.Biophys.Res.Commun., 451, 2014