4WN0 | | XENOPUS LAEVIS EMBRYONIC EPIDERMAL LECTIN IN COMPLEX WITH GLYCEROL PHOSPHATE | | Descriptor: | XEEL protein, CALCIUM ION, PHOSPHATE ION, ... | | Authors: | Wangkanont, K., Kiessling, L.L., Forest, K.T. | | Deposit date: | 2014-10-10 | | Release date: | 2016-01-20 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.
J.Biol.Chem., 291, 2016
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4WPB | | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH ALPHA/BETA-VEGF-1 | | Descriptor: | Vascular endothelial growth factor A, alpha/beta-VEGF-1 | | Authors: | Kreitler, D.F., Checco, J.W., Gellman, S.H., Forest, K.T. | | Deposit date: | 2014-10-17 | | Release date: | 2015-04-15 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Targeting diverse protein-protein interaction interfaces with alpha / beta-peptides derived from the Z-domain scaffold.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4XGK | | CRYSTAL STRUCUTRE OF UDP-GALACTOPYRANOSE MUTASE FROM CORYNEBACTERIUM DIPHTHERIAE IN COMPLEX WITH 2-[4-(4-CHLOROPHENYL)-7-(2-THIENYL)-2-THIA-5,6,8,9-TETRAZABICYCLO[4.3.0]NONA-4,7,9-TRIEN-3-YL]ACETIC | | Descriptor: | UDP-galactopyranose mutase, SULFATE ION, [(7S)-6-(4-chlorophenyl)-3-(thiophen-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetic acid, ... | | Authors: | Wangkanont, K., Heroux, A., Forest, K.T., Kiessling, L.L. | | Deposit date: | 2014-12-31 | | Release date: | 2015-08-12 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.652 Å) | | Cite: | Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents.
Acs Chem.Biol., 10, 2015
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4XJJ | |
4Z1W | | CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F FROM SYNCHROTRON | | Descriptor: | Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid | | Authors: | Bhattacharya, S., Satyshur, K.A., Wangkanont, K., Lehtivuori, H., Forest, K.T. | | Deposit date: | 2015-03-27 | | Release date: | 2016-01-20 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
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4ZRR | | CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F AT 1.5 A RESOLUTION USING A HOME SOURCE. | | Descriptor: | Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... | | Authors: | Bhattacharya, S., Satyshur, K.A., Lehtivuori, H., Forest, K.T. | | Deposit date: | 2015-05-12 | | Release date: | 2016-01-20 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
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5BR7 | | STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM CORYNEBACTERIUM DIPHTHERIAE IN COMPLEX WITH CITRATE ION | | Descriptor: | UDP-galactopyranose mutase, FLAVIN-ADENINE DINUCLEOTIDE, 1,2-ETHANEDIOL, ... | | Authors: | Wangkanont, K., Kiessling, L.L., Forest, K.T. | | Deposit date: | 2015-05-29 | | Release date: | 2016-06-01 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Conformational Control of UDP-Galactopyranose Mutase Inhibition.
Biochemistry, 56, 2017
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5BRJ | |
5CGN | | STRUCTURE OF QUASIRACEMIC ALA-MAGAININ 2 WITH A BETA AMINO ACID SUBSTITUTION AT POSITION 8 | | Descriptor: | D-Ala-Magainin Derivative, L-ACPC8-Ala-Magainin, CHLORIDE ION | | Authors: | Hayouka, Z., Thomas, N.C., Mortenson, D.E., Satyshur, K.A., Weisblum, B., Forest, K.T., Gellman, S.H. | | Deposit date: | 2015-07-09 | | Release date: | 2015-09-23 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.
J.Am.Chem.Soc., 137, 2015
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5CGO | | STRUCTURE OF QUASIRACEMIC ALA-MAGAININ 2 WITH A BETA AMINO ACID SUBSTITUTION AT POSITION 13 | | Descriptor: | ACPC-13 derivative of Ala-Magainin 2, D-Ala-Magainin 2 | | Authors: | Hayouka, Z., Thomas, N.C., Mortenson, D.E., Satyshur, K.A., Weisblum, B., Forest, K.T., Gellman, S.H. | | Deposit date: | 2015-07-09 | | Release date: | 2015-09-23 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.
J.Am.Chem.Soc., 137, 2015
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5EQD | |
5EQF | | CRYSTAL STRUCUTRE OF OXIDIZED UDP-GALACTOPYRANOSE MUTASE FROM CORYNEBACTERIUM DIPHTHERIAE WITH UDP BOUND IN CLOSED FORM | | Descriptor: | UDP-galactopyranose mutase, URIDINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Wangkanont, K., Kiessling, L.L., Forest, K.T. | | Deposit date: | 2015-11-12 | | Release date: | 2016-11-23 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.145 Å) | | Cite: | Conformational Control of UDP-Galactopyranose Mutase Inhibition.
Biochemistry, 56, 2017
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5ER9 | |
5F3R | |
5I1N | | VILLIN HEADPIECE SUBDOMAIN WITH A GLN26 TO BETA-3-HOMOGLUTAMINE SUBSTITUTION | | Descriptor: | Villin-1, D-Villin headpiece subdomain | | Authors: | Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T. | | Deposit date: | 2016-02-05 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5I1O | | VILLIN HEADPIECE SUBDOMAIN WITH A GLN26 TO ACPC SUBSTITUTION | | Descriptor: | Villin-1, D-Villin headpiece subdomain | | Authors: | Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T. | | Deposit date: | 2016-02-05 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.348 Å) | | Cite: | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5I1P | | VILLIN HEADPIECE SUBDOMAIN WITH A LYS30 TO BETA-3-HOMOLYSINE SUBSTITUTION | | Descriptor: | Villin-1, D-Villin headpiece subdomain, ETHANOL | | Authors: | Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T. | | Deposit date: | 2016-02-05 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5I1S | | VILLIN HEADPIECE SUBDOMAIN WITH A LYS30 TO APC SUBSTITUTION | | Descriptor: | Villin-1, D-Villin headpiece subdomain | | Authors: | Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T. | | Deposit date: | 2016-02-05 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
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5IC5 | | BACTERIOPHYTOCHROME RESPONSE REGULATOR RTBRR | | Descriptor: | Candidate response regulator, CheY, ZINC ION, ... | | Authors: | Baker, A.W., Satyshur, K.A., Forest, K.T. | | Deposit date: | 2016-02-22 | | Release date: | 2016-03-02 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Arm-in-Arm Response Regulator Dimers Promote Intermolecular Signal Transduction.
J.Bacteriol., 198, 2016
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5U48 | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 5-[(1E)-2-(4-BORONIC ACID)ETHENYL]-1,3-BENZENEDIOL | | Descriptor: | Transthyretin, {4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl}boronic acid | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U49 | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 5-[(1E)-2-(2-CHLORO-4-HYDROXYPHENYL)ETHENYL]-1,3-BENZENEDIOL | | Descriptor: | Transthyretin, 5-[(E)-2-(2-chloro-4-hydroxyphenyl)ethenyl]benzene-1,3-diol | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4A | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 5-[(1E)-2-(2-CHLORO-4-BORONIC ACID)ETHENYL]-1,3-BENZENEDIOL | | Descriptor: | Transthyretin, {3-chloro-4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl}boronic acid | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4B | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 3-[(1E)-2-(4-HYDROXYPHENYL)ETHENYL]BENZOIC ACID | | Descriptor: | Transthyretin, 3-[(E)-2-(4-hydroxyphenyl)ethenyl]benzoic acid | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.448 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4C | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 3-[(1E)-2-(4-BORONIC ACID)ETHENYL]BENZOIC ACID | | Descriptor: | Transthyretin, 3-[(E)-2-(4-boronophenyl)ethenyl]benzoic acid | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4D | | WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 3-[(1E)-2-(2-CHLORO-4-HYDROXYPHENYL)ETHENYL]BENZOIC ACID | | Descriptor: | Transthyretin, 3-[(E)-2-(2-chloro-4-hydroxyphenyl)ethenyl]benzoic acid | | Authors: | Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T. | | Deposit date: | 2016-12-03 | | Release date: | 2017-09-27 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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