Author results

2X38
  • Download 2x38
  • View 2x38
Molmil generated image of 2x38
THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH IC87114.
分子名称:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, 2-[(6-AMINO-9H-PURIN-9-YL)METHYL]-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE
著者Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
登録日2010-01-22
公開日2010-02-02
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
3CM8
  • Download 3cm8
  • View 3cm8
Molmil generated image of 3cm8
A RNA POLYMERASE SUBUNIT STRUCTURE FROM VIRUS
分子名称:Polymerase acidic protein, peptide from RNA-directed RNA polymerase catalytic subunit
著者He, X., Zhou, J., Zeng, Z., Ma, J., Zhang, R., Rao, Z., Liu, Y.
登録日2008-03-21
公開日2008-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus
Nature, 454, 2008
3CXR
  • Download 3cxr
  • View 3cxr
Molmil generated image of 3cxr
CRYSTAL STRUCTURE OF GLUCONATE 5-DEHYDROGASE FROM STREPTOCOCCUS SUIS TYPE 2
分子名称:Dehydrogenase with different specificities
著者Peng, H., Gao, F., Zhang, Q., Liu, Y., Gao, G.F.
登録日2008-04-25
公開日2009-03-17
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes.
Protein Sci., 18, 2009
3EBJ
  • Download 3ebj
  • View 3ebj
Molmil generated image of 3ebj
CRYSTAL STRUCTURE OF AN AVIAN INFLUENZA VIRUS PROTEIN
分子名称:Polymerase acidic protein, MAGNESIUM ION
著者Yuan, P., Bartlam, M., Lou, Z., Chen, S., Rao, Z., Liu, Y.
登録日2008-08-27
公開日2009-02-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
3ERW
  • Download 3erw
  • View 3erw
Molmil generated image of 3erw
CRYSTAL STRUCTURE OF STOA FROM BACILLUS SUBTILIS
分子名称:Sporulation thiol-disulfide oxidoreductase A
著者Crow, A., Liu, Y., Moller, M.C., Le Brun, N.E., Hederstedt, L.
登録日2008-10-03
公開日2009-01-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Functional Properties of Bacillus subtilis Endospore Biogenesis Factor StoA
J.Biol.Chem., 284, 2009
3F5A
  • Download 3f5a
  • View 3f5a
Molmil generated image of 3f5a
CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 3'SIALACNAC1-3
分子名称:Micronemal protein 1, CHLORIDE ION, O-SIALIC ACID, ...
著者Garnett, J.A., Liu, Y., Feizi, T., Matthews, S.J.
登録日2008-11-03
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
3F5E
  • Download 3f5e
  • View 3f5e
Molmil generated image of 3f5e
CRYSTAL STRUCTURE OF TOXOPLASMA GONDII MICRONEMAL PROTEIN 1 BOUND TO 2'F-3'SIALACNAC1-3
分子名称:Micronemal protein 1, CHLORIDE ION, O-SIALIC ACID, ...
著者Garnett, J.A., Liu, Y., Feizi, T., Matthews, S.J.
登録日2008-11-03
公開日2009-07-28
最終更新日2016-02-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Sci., 18, 2009
3LNW
  • Download 3lnw
  • View 3lnw
Molmil generated image of 3lnw
CLOSE CORRELATION OF PROTEIN THERMOSTABILITY AND SELF-BURIED AREA RATE REVEALED BY CRYSTAL STRUCTURE OF HPR FROM THERMOANAEROBACTER TENGCONGENSIS MB4
分子名称:Phosphotransferase system, HPr-related proteins
著者Gao, G.G., Feng, C., Gao, F., Liu, Y.
登録日2010-02-03
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Close correlation of protein thermostability and self-buried area rate revealed by crystal structure of HPr from Thermoanaerobacter tengcongensis MB4
To be Published
3O03
  • Download 3o03
  • View 3o03
Molmil generated image of 3o03
QUATERNARY COMPLEX STRUCTURE OF GLUCONATE 5-DEHYDROGENASE FROM STREPTOCOCCUS SUIS TYPE 2
分子名称:Dehydrogenase with different specificities, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Peng, H., Gao, F., Zhang, Q., Liu, Y., Gao, G.F.
登録日2010-07-18
公開日2010-12-15
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insight Into the Catalytic Mechanism of Gluconate 5-Dehydrogenase from Streptococcus Suis: Crystal Structures of the Substrate-Free and Quaternary Complex Enzymes.
Protein Sci., 18, 2009
3R27
  • Download 3r27
  • View 3r27
Molmil generated image of 3r27
CRYSTAL STRUCTURE OF THE FIRST RRM DOMAIN OF HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L (HNRNP L)
分子名称:Heterogeneous nuclear ribonucleoprotein L, GLYCEROL
著者Zhang, W., Liu, Y., Zeng, F., Niu, L., Teng, M., Li, X.
登録日2011-03-14
公開日2011-09-14
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)
To be Published
3RJ2
  • Download 3rj2
  • View 3rj2
Molmil generated image of 3rj2
STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A NOVEL HISTONE H3 BINDING PROTEIN ORF158L FROM THE SINGAPORE GROUPER IRIDOVIRUS (SGIV)
分子名称:Putative uncharacterized protein
著者Chen, L., Liu, Y., Sivaraman, J., Hew, C.L.
登録日2011-04-15
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel histone H3 binding protein ORF158L from the Singapore grouper iridovirus
J.Virol., 85, 2011
3UA3
  • Download 3ua3
  • View 3ua3
Molmil generated image of 3ua3
CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5 IN COMPLEX WITH SAH
分子名称:Protein arginine N-methyltransferase 5, S-ADENOSYL-L-HOMOCYSTEINE
著者Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M.
登録日2011-10-20
公開日2011-12-14
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
3UA4
  • Download 3ua4
  • View 3ua4
Molmil generated image of 3ua4
CRYSTAL STRUCTURE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT5
分子名称:Protein arginine N-methyltransferase 5, GLYCEROL
著者Sun, L., Wang, M., Lv, Z., Yang, N., Liu, Y., Bao, S., Gong, W., Xu, R.M.
登録日2011-10-21
公開日2011-12-14
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural insights into protein arginine symmetric dimethylation by PRMT5
Proc.Natl.Acad.Sci.USA, 108, 2011
4A5V
  • Download 4a5v
  • View 4a5v
Molmil generated image of 4a5v
SOLUTION STRUCTURE ENSEMBLE OF THE TWO N-TERMINAL APPLE DOMAINS (RESIDUES 58-231) OF TOXOPLASMA GONDII MICRONEME PROTEIN 4
分子名称:MICRONEMAL PROTEIN 4
著者Marchant, J., Cowper, B., Liu, Y., Lai, L., Pinzan, C., Marq, J.B., Friedrich, N., Sawmynaden, K., Chai, W., Childs, R.A., Saouros, S., Simpson, P., Barreira, M.C.R., Feizi, T., Soldati-Favre, D., Matthews, S.
登録日2011-10-28
公開日2012-04-04
最終更新日2012-05-23
実験手法SOLUTION NMR
主引用文献Galactose Recognition by the Apicomplexan Parasite Toxoplasma Gondii.
J.Biol.Chem., 287, 2012
4AOT
  • Download 4aot
  • View 4aot
Molmil generated image of 4aot
CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 (LOK) BOUND TO GW830263A
分子名称:Serine/threonine-protein kinase 10, CHLORIDE ION, 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea
著者Elkins, J.M., Salah, E., Szklarz, M., Canning, P., von Delft, F., Yue, W., Liu, Y., Bountra, C., Arrowsmith, C., Edwards, A., Knapp, S.
登録日2012-03-29
公開日2012-04-11
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal Structure of Human Serine Threonine Kinase-10 (Lok) Bound to Gw830263A
To be Published
4AZA
  • Download 4aza
  • View 4aza
Molmil generated image of 4aza
IMPROVED EIF4E BINDING PEPTIDES BY PHAGE DISPLAY GUIDED DESIGN.
分子名称:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EIF4G1_D5S PEPTIDE, [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE
著者Chew, W.Z., Quah, S.T., Verma, C.S., Liu, Y., Lane, D.P., Brown, C.J.
登録日2012-06-25
公開日2012-08-08
最終更新日2013-03-06
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Improved Eif4E Binding Peptides by Phage Display Guided Design: Plasticity of Interacting Surfaces Yield Collective Effects.
Plos One, 7, 2012
4CUP
  • Download 4cup
  • View 4cup
Molmil generated image of 4cup
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-1 N09421
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, 4-Fluorobenzamidoxime, METHANOL
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-1 N09421
To be Published
4CUQ
  • Download 4cuq
  • View 4cuq
Molmil generated image of 4cuq
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-2 N09594
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, 4-[(3S)-3-hydroxy-3-methoxypropyl]phenol
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-2 N09594
To be Published
4CUR
  • Download 4cur
  • View 4cur
Molmil generated image of 4cur
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-3 N09555
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, 1,2-ETHANEDIOL, 2-(hydroxymethyl)-6-methylpyridin-3-ol
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.842 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-3 N09553
To be Published
4CUS
  • Download 4cus
  • View 4cus
Molmil generated image of 4cus
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-4 N09496
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, 1,2-ETHANEDIOL, quinolin-4-ol
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-4 N09496
To be Published
4CUT
  • Download 4cut
  • View 4cut
Molmil generated image of 4cut
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-5 N09428
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), 1,2-ETHANEDIOL
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.835 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-5 N09428
To be Published
4CUU
  • Download 4cuu
  • View 4cuu
Molmil generated image of 4cuu
CRYSTAL STRUCTURE OF HUMAN BAZ2B IN COMPLEX WITH FRAGMENT-6 N09645
分子名称:BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B, (2R)-1,2,3,4-tetrahydroquinoline-2,7-diol, 1,2-ETHANEDIOL
著者Bradley, A.R., Liu, Y., Krojer, T., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., von Delft, F.
登録日2014-03-21
公開日2014-04-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Crystal Structure of Human Baz2B in Complex with Fragment-6 N09645
To be Published
4D0Q
  • Download 4d0q
  • View 4d0q
Molmil generated image of 4d0q
HYALURONAN BINDING MODULE OF THE STREPTOCOCCAL PNEUMONIAE HYALURONATE LYASE
分子名称:HYALURONATE LYASE, 1,2-ETHANEDIOL
著者Suits, M.D.L., Pluvinage, B., Law, A., Liu, Y., Palma, A.S., Chai, W., Feizi, T., Boraston, A.B.
登録日2014-04-29
公開日2014-08-06
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Conformational Analysis of the Streptococcus Pneumoniae Hyaluronate Lyase and Characterization of its Hyaluronan-Specific Carbohydrate-Binding Module.
J.Biol.Chem., 289, 2014
4EFO
  • Download 4efo
  • View 4efo
Molmil generated image of 4efo
CRYSTAL STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN OF HUMAN TBK1
分子名称:Serine/threonine-protein kinase TBK1
著者Li, J., Li, J., Miyahira, A., Sun, J., Liu, Y., Cheng, G., Liang, H.
登録日2012-03-30
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献Crystal structure of the ubiquitin-like domain of human TBK1.
Protein Cell, 3, 2012
4FVK
  • Download 4fvk
  • View 4fvk
Molmil generated image of 4fvk
STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF NEURAMINIDASE-LIKE MOLECULE N10 DERIVED FROM BAT INFLUENZA A VIRUS
分子名称:Neuraminidase, CALCIUM ION, ZINC ION, ...
著者Li, Q., Sun, X.M., Li, Z.X., Liu, Y., Vavricka, C.J., Qi, J.X., Gao, G.F.
登録日2012-06-29
公開日2012-09-19
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
Proc.Natl.Acad.Sci.USA, 109, 2012