Author results

4EAK
  • Download 4eak
  • View 4eak
Molmil generated image of 4eak
CO-CRYSTAL STRUCTURE OF AN AMPK CORE WITH ATP
分子名称:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
登録日2012-03-22
公開日2012-06-06
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAL
  • Download 4eal
  • View 4eal
Molmil generated image of 4eal
CO-CRYSTAL OF AMPK CORE WITH ATP SOAKED WITH AMP
分子名称:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
登録日2012-03-22
公開日2012-06-06
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4IXP
  • Download 4ixp
  • View 4ixp
Molmil generated image of 4ixp
CRYSTAL STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK)
分子名称:Maternal embryonic leucine zipper kinase
著者Cao, L.S., Wang, J., Wang, Z.X., Wu, J.W.
登録日2013-01-27
公開日2013-09-11
実験手法X-RAY DIFFRACTION (2.749 Å)
主引用文献Structural basis for the regulation of maternal embryonic leucine zipper kinase.
Plos One, 8, 2013
4N77
  • Download 4n77
  • View 4n77
Molmil generated image of 4n77
CRYSTAL STRUCTURE OF CAS PROTEIN
分子名称:Uncharacterized protein
著者Tian, W., Sheng, G., Zhao, H., Wang, J., Wang, Y.
登録日2013-10-15
公開日2014-10-15
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal strucute studies of CasD
To be Published
4Z0B
  • Download 4z0b
  • View 4z0b
Molmil generated image of 4z0b
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ANTI-OFLOXACIN ANTIBODY AND EXPLORATION ITS RECEPTOR BINDING SITE
分子名称:antibody heavy chain, antibody light chain, PHOSPHATE ION
著者He, K., Du, X., Sheng, W., Zhou, X., Wang, J., Wang, S.
登録日2015-03-26
公開日2016-04-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding.
J.Agric.Food Chem., 64, 2016
5G2X
  • Download 5g2x
  • View 5g2x
Molmil generated image of 5g2x
STRUCTURE A OF GROUP II INTRON COMPLEXED WITH ITS REVERSE TRANSCRIPTASE
分子名称:GROUP II INTRON, 5'-R(*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*CP)-3', GROUP II INTRON-ENCODED PROTEIN LTRA
著者Qu, G., Kaushal, P.S., Wang, J., Shigematsu, H., Piazza, C.L., Agrawal, R.K., Belfort, M., Wang, H.W.
登録日2016-04-16
公開日2016-05-11
最終更新日2016-06-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of a Group II Intron in Complex with its Reverse Transcriptase.
Nat.Struct.Mol.Biol., 23, 2016
5G2Y
  • Download 5g2y
  • View 5g2y
Molmil generated image of 5g2y
STRUCTURE A OF GROUP II INTRON COMPLEXED WITH ITS REVERSE TRANSCRIPTASE
分子名称:GROUP II INTRON
著者Qu, G., Kaushal, P.S., Wang, J., Shigematsu, H., Piazza, C.L., Agrawal, R.K., Belfort, M., Wang, H.W.
登録日2016-04-16
公開日2016-05-04
最終更新日2016-06-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of a Group II Intron in Complex with its Reverse Transcriptase.
Nat.Struct.Mol.Biol., 23, 2016
5GXO
  • Download 5gxo
  • View 5gxo
Molmil generated image of 5gxo
DISCOVERY OF A COMPOUND THAT ACTIVATES SIRT3 TO DEACETYLATE MANGANESE SUPEROXIDE DISMUTASE
分子名称:Superoxide dismutase [Mn], mitochondrial, MANGANESE (II) ION
著者Lu, J., Li, J., Wu, M., Wang, J., Xia, Q.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Free Radic. Biol. Med., 112, 2017
5X6G
  • Download 5x6g
  • View 5x6g
Molmil generated image of 5x6g
CRYSTAL STRUCTURE OF SMAD5-MH1/PALINDROMIC SBE DNA COMPLEX
分子名称:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3'), ...
著者Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
登録日2017-02-21
公開日2017-03-15
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5X6H
  • Download 5x6h
  • View 5x6h
Molmil generated image of 5x6h
CRYSTAL STRUCTURE OF SMAD5-MH1/GC-BRE DNA COMPLEX
分子名称:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3'), ZINC ION
著者Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
登録日2017-02-22
公開日2017-03-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5X6M
  • Download 5x6m
  • View 5x6m
Molmil generated image of 5x6m
CRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
分子名称:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), ...
著者Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
登録日2017-02-22
公開日2017-03-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5XOU
  • Download 5xou
  • View 5xou
Molmil generated image of 5xou
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 7T8 ON THE GUIDE STRAND
分子名称:TtAgo (D546N), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*TP*GP*GP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), ...
著者Sheng, G., Wang, J., Zhao, H., Wang, Y.
登録日2017-05-31
公開日2017-10-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
5XOW
  • Download 5xow
  • View 5xow
Molmil generated image of 5xow
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 6'A7' ON THE TARGET STRAND
分子名称:TtAgo (D546N), DNA (5'-D(P*(TD)P*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), RNA (5'-R(P*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*AP*CP*CP*UP*CP*G)-3'), ...
著者Sheng, G., Wang, J., Zhao, H., Wang, Y.
登録日2017-05-31
公開日2017-10-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
5XP8
  • Download 5xp8
  • View 5xp8
Molmil generated image of 5xp8
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 4A5 ON THE GUIDE STRAND
分子名称:TtAgo, DNA (5'-D(P*TP*GP*AP*GP*AP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3'), DNA (5'-D(*CP*AP*AP*CP*C*AP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), ...
著者Sheng, G., Gogakos, T., Wang, J., Zhao, H., Serganov, A., Juranek, S., Tuschl, T., Patel, J.D., Wang, Y.
登録日2017-06-01
公開日2018-04-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.
Nucleic Acids Res., 45, 2017
5XPA
  • Download 5xpa
  • View 5xpa
Molmil generated image of 5xpa
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 9'U10' ON THE TARGET STRAND
分子名称:Uncharacterized protein Ago, DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), RNA (5'-R(P*AP*UP*AP*CP*AP*AP*CP*CP*GP*UP*UP*CP*UP*AP*CP*UP*CP*CP*G)-3'), ...
著者Sheng, G., Gogakos, T., Wang, J., Zhao, H., Serganov, A., Juranek, S., Tuschl, T., Patel, J.D., Wang, Y.
登録日2017-06-01
公開日2018-04-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.
Nucleic Acids Res., 45, 2017
5XPG
  • Download 5xpg
  • View 5xpg
Molmil generated image of 5xpg
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 6'U7' ON THE TARGET STRAND
分子名称:Uncharacterized protein, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3', 5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3', ...
著者Sheng, G., Gogakos, T., Wang, J., Zhao, H., Serganov, A., Juranek, S., Tuschl, T., Patel, J.D., Wang, Y.
登録日2017-06-02
公開日2018-04-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.
Nucleic Acids Res., 45, 2017
5XQ2
  • Download 5xq2
  • View 5xq2
Molmil generated image of 5xq2
CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE PROTEIN COMPLEXED WITH A BULGE 5A6 ON THE GUIDE STRAND
分子名称:TtAgo (D546N), DNA (5'-D(P*TP*GP*AP*AP*GP*AP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), ...
著者Sheng, G., Gogakos, T., Wang, J., Zhao, H., Serganov, A., Juranek, S., Tuschl, T., Patel, D., Wang, Y.
登録日2017-06-06
公開日2017-10-04
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
5YKH
  • Download 5ykh
  • View 5ykh
Molmil generated image of 5ykh
CRYSTAL STRUCTURE OF THE ENGINEERED NINE-REPEAT PUF DOMAIN
分子名称:Pumilio homolog 1, PHOSPHATE ION
著者Zhao, Y.Y., Wang, J., Li, H.T., Wang, Z.X., Wu, J.W.
登録日2017-10-14
公開日2018-03-14
最終更新日2018-06-06
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Expanding RNA binding specificity and affinity of engineered PUF domains.
Nucleic Acids Res., 46, 2018
5YKI
  • Download 5yki
  • View 5yki
Molmil generated image of 5yki
CRYSTAL STRUCTURE OF THE ENGINEERED NINE-REPEAT PUF DOMAIN IN COMPLEX WITH COGNATE 9NT-RNA
分子名称:Pumilio homolog 1, RNA (5'-R(*UP*GP*UP*UP*GP*UP*AP*UP*A)-3')
著者Zhao, Y.Y., Wang, J., Li, H.T., Wang, Z.X., Wu, J.W.
登録日2017-10-14
公開日2018-03-14
最終更新日2018-06-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Expanding RNA binding specificity and affinity of engineered PUF domains.
Nucleic Acids Res., 46, 2018
5YZ0
  • Download 5yz0
  • View 5yz0
Molmil generated image of 5yz0
CRYO-EM STRUCTURE OF HUMAN ATR-ATRIP COMPLEX
分子名称:Serine/threonine-protein kinase ATR, ATR-interacting protein
著者Rao, Q., Liu, M., Tian, Y., Wu, Z., Wang, H., Wang, J., Xu, Y.
登録日2017-12-11
公開日2018-01-31
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of human ATR-ATRIP complex.
Cell Res., 28, 2018
5ZAK
  • Download 5zak
  • View 5zak
Molmil generated image of 5zak
CRYO-EM STRUCTURE OF HUMAN DICER AND ITS COMPLEXES WITH A PRE-MIRNA SUBSTRATE
分子名称:Endoribonuclease Dicer, RISC-loading complex subunit TARBP2
著者Liu, Z., Wang, J., Cheng, H., Ke, X., Sun, L., Zhang, Q.C., Wang, H.-W.
登録日2018-02-07
公開日2018-05-09
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
5ZAL
  • Download 5zal
  • View 5zal
Molmil generated image of 5zal
CRYO-EM STRUCTURE OF HUMAN DICER AND ITS COMPLEXES WITH A PRE-MIRNA SUBSTRATE
分子名称:Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer)
著者Liu, Z., Wang, J., Cheng, H., Ke, X., Sun, L., Zhang, Q.C., Wang, H.-W.
登録日2018-02-07
公開日2018-05-09
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
5ZAM
  • Download 5zam
  • View 5zam
Molmil generated image of 5zam
CRYO-EM STRUCTURE OF HUMAN DICER AND ITS COMPLEXES WITH A PRE-MIRNA SUBSTRATE
分子名称:Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer)
著者Liu, Z., Wang, J., Cheng, H., Ke, X., Sun, L., Zhang, Q.C., Wang, H.-W.
登録日2018-02-07
公開日2018-05-09
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate.
Cell, 173, 2018
5ZTE
  • Download 5zte
  • View 5zte
Molmil generated image of 5zte
CRYSTAL STRUCTURE OF PRXA C119S MUTANT FROM ARABIDOPSIS THALIANA
分子名称:2-Cys peroxiredoxin BAS1, chloroplastic
著者Yang, Y., Cai, W., Wang, J., Pan, W., Liu, L., Wang, M., Zhang, M.
登録日2018-05-03
公開日2018-10-10
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6KY4
  • Download 6ky4
  • View 6ky4
Molmil generated image of 6ky4
CRYSTAL STRUCTURE OF SULFIREDOXIN FROM ARABIDOPSIS THALIANA
分子名称:Sulfiredoxin, chloroplastic/mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ...
著者Liu, M., Wang, J., Li, X., Li, M., Sylvanno, M.J., Zhang, M., Wang, M.
登録日2019-09-16
公開日2019-10-16
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of sulfiredoxin from Arabidopsis thaliana revealed a more robust antioxidant mechanism in plants.
Biochem.Biophys.Res.Commun., 520, 2019