Author results

3QVJ
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ALLANTOIN RACEMASE FROM KLEBSIELLA PNEUMONIAE
Descriptor:Putative hydantoin racemase, CHLORIDE ION
Authors:French, J.B., Neau, D.B., Ealick, S.E.
Deposit date:2011-02-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase.
J.Mol.Biol., 410, 2011
3QVK
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ALLANTOIN RACEMASE FROM KLEBSIELLA PNEUMONIAE
Descriptor:Putative hydantoin racemase, 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA
Authors:French, J.B., Neau, D.B., Ealick, S.E.
Deposit date:2011-02-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase.
J.Mol.Biol., 410, 2011
3QVL
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ALLANTOIN RACEMASE FROM KLEBSIELLA PNEUMONIAE
Descriptor:Putative hydantoin racemase, [(4R)-2,5-dioxoimidazolidin-4-yl]acetic acid
Authors:French, J.B., Neau, D.B., Ealick, S.E.
Deposit date:2011-02-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.822 Å)
Cite:Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase.
J.Mol.Biol., 410, 2011
3QW3
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STRUCTURE OF LEISHMANIA DONOVANI OMP DECARBOXYLASE
Descriptor:Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative (Ompdcase-oprtase, putative), ...
Authors:French, J.B., Ealick, S.E.
Deposit date:2011-02-26
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
3QW4
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STRUCTURE OF LEISHMANIA DONOVANI UMP SYNTHASE
Descriptor:UMP synthase, URIDINE-5'-MONOPHOSPHATE, CHLORIDE ION
Authors:French, J.B., Ealick, S.E.
Deposit date:2011-02-26
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
J.Biol.Chem., 286, 2011
3RI6
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A NOVEL MECHANISM OF SULFUR TRANSFER CATALYZED BY O-ACETYLHOMOSERINE SULFHYDRYLASE IN METHIONINE BIOSYNTHETIC PATHWAY OF WOLINELLA SUCCINOGENES
Descriptor:O-ACETYLHOMOSERINE SULFHYDRYLASE
Authors:Tran, T.H., Krishnamoorthy, K., Begley, T.P., Ealick, S.E.
Deposit date:2011-04-13
Release date:2011-08-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes.
Acta Crystallogr.,Sect.D, 67, 2011
3RM5
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STRUCTURE OF TRIFUNCTIONAL THI20 FROM YEAST
Descriptor:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20, SULFATE ION
Authors:French, J.B., Begley, T.P., Ealick, S.E.
Deposit date:2011-04-20
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of trifunctional THI20 from yeast.
Acta Crystallogr.,Sect.D, 67, 2011
3RW9
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CRYSTAL STRUCTURE OF HUMAN SPERMIDINE SYNTHASE IN COMPLEX WITH DECARBOXYLATED S-ADENOSYLHOMOCYSTEINE
Descriptor:Spermidine synthase, 5'-S-(3-aminopropyl)-5'-thioadenosine
Authors:Seckute, J., McCloskey, D.E., Thomas, H.J., Secrist III, J.A., Pegg, A.E., Ealick, S.E.
Deposit date:2011-05-08
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
Protein Sci., 20, 2011
3UAV
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CRYSTAL STRUCTURE OF ADENOSINE PHOSPHORYLASE FROM BACILLUS CEREUS
Descriptor:Purine nucleoside phosphorylase deoD-type, SULFATE ION, GLYCEROL
Authors:Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M.G., Sgarrella, F., Ealick, S.E.
Deposit date:2011-10-22
Release date:2012-02-29
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
3UAW
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CRYSTAL STRUCTURE OF ADENOSINE PHOSPHORYLASE FROM BACILLUS CEREUS COMPLEXED WITH ADENOSINE
Descriptor:Purine nucleoside phosphorylase deoD-type, ADENOSINE, SULFATE ION, ...
Authors:Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M.G., Sgarrella, F., Ealick, S.E.
Deposit date:2011-10-22
Release date:2012-02-29
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
3UAX
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CRYSTAL STRUCTURE OF ADENOSINE PHOSPHORYLASE FROM BACILLUS CEREUS COMPLEXED WITH INOSINE
Descriptor:Purine nucleoside phosphorylase deoD-type, INOSINE, SULFATE ION, ...
Authors:Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M.G., Sgarrella, F., Ealick, S.E.
Deposit date:2011-10-22
Release date:2012-02-29
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
3UAY
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CRYSTAL STRUCTURE OF BACILLUS CEREUS ADENOSINE PHOSPHORYLASE D204N MUTANT COMPLEXED WITH ADENOSINE
Descriptor:Purine nucleoside phosphorylase deoD-type, ADENOSINE, SULFATE ION, ...
Authors:Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M.G., Sgarrella, F., Ealick, S.E.
Deposit date:2011-10-22
Release date:2012-02-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
3UAZ
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CRYSTAL STRUCTURE OF BACILLUS CEREUS ADENOSINE PHOSPHORYLASE D204N MUTANT COMPLEXED WITH INOSINE
Descriptor:Purine nucleoside phosphorylase deoD-type, INOSINE, SULFATE ION, ...
Authors:Dessanti, P., Zhang, Y., Allegrini, S., Tozzi, M.G., Sgarrella, F., Ealick, S.E.
Deposit date:2011-10-22
Release date:2012-02-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
4ESW
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CRYSTAL STRUCTURE OF C. ALBICANS THI5 H66G MUTANT
Descriptor:Pyrimidine biosynthesis enzyme THI13, CITRIC ACID
Authors:Fenwick, M.K., Huang, S., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
4ESX
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CRYSTAL STRUCTURE OF C. ALBICANS THI5 COMPLEXED WITH PLP
Descriptor:Pyrimidine biosynthesis enzyme THI13
Authors:Huang, S., Fenwick, M.K., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
4GIJ
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CRYSTAL STRUCTURE OF PSEUDOURIDINE MONOPHOSPHATE GLYCOSIDASE COMPLEXED WITH SULFATE
Descriptor:Pseudouridine-5'-phosphate glycosidase, SULFATE ION, MANGANESE (II) ION
Authors:Huang, S., Mahanta, N., Begley, T.P., Ealick, S.E.
Deposit date:2012-08-08
Release date:2012-10-31
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.941 Å)
Cite:Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4GIK
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CRYSTAL STRUCTURE OF PSEUDOURIDINE MONOPHOSPHATE GLYCOSIDASE/LINEAR R5P ADDUCT
Descriptor:Pseudouridine-5'-phosphate glycosidase, RIBOSE-5-PHOSPHATE, MANGANESE (II) ION
Authors:Huang, S., Mahanta, N., Begley, T.P., Ealick, S.E.
Deposit date:2012-08-08
Release date:2012-10-31
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4GIL
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CRYSTAL STRUCTURE OF PSEUDOURIDINE MONOPHOSPHATE GLYCOSIDASE/LINEAR PSEUDOURIDINE 5'-PHOSPHATE ADDUCT
Descriptor:Pseudouridine-5'-phosphate glycosidase, MANGANESE (II) ION, pseudouridine 5'-phosphate, ...
Authors:Huang, S., Mahanta, N., Begley, T.P., Ealick, S.E.
Deposit date:2012-08-08
Release date:2012-10-31
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.539 Å)
Cite:Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4GIM
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CRYSTAL STRUCTURE OF PSEUDOURIDINE MONOPHOSPHATE GLYCOSIDASE COMPLEXED WITH PSEUDOURIDINE 5'-PHOSPHATE
Descriptor:Pseudouridine-5'-phosphate glycosidase, PSEUDOURIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION
Authors:Huang, S., Mahanta, N., Begley, T.P., Ealick, S.E.
Deposit date:2012-08-08
Release date:2012-10-31
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4HHE
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QUINOLINATE SYNTHASE FROM PYROCOCCUS FURIOSUS
Descriptor:Quinolinate synthase A, CHLORIDE ION
Authors:Soriano, E.V., Zhang, Y., Settembre, E.C., Colabroy, K., Sanders, J.M., Dorrestein, P.C., Begley, T.P., Ealick, S.E.
Deposit date:2012-10-09
Release date:2013-08-28
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Active-site models for complexes of quinolinate synthase with substrates and intermediates.
Acta Crystallogr.,Sect.D, 69, 2013
4JEL
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STRUCTURE OF MILB STREPTOMYCES RIMOFACIENS CMP N-GLYCOSIDASE
Descriptor:CMP/hydroxymethyl CMP hydrolase, SULFATE ION
Authors:Sikowitz, M.D., Cooper, L.E., Begley, T.P., Kaminski, P.A., Ealick, S.E.
Deposit date:2013-02-27
Release date:2013-09-11
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
4JEM
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CRYSTAL STRUCTURE OF MILB COMPLEXED WITH CYTIDINE 5'-MONOPHOSPHATE
Descriptor:CMP/hydroxymethyl CMP hydrolase, CYTIDINE-5'-MONOPHOSPHATE
Authors:Sikowitz, M.D., Cooper, L.E., Begley, T.P., Kaminski, P.A., Ealick, S.E.
Deposit date:2013-02-27
Release date:2013-09-11
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
4JEN
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STRUCTURE OF CLOSTRIDIUM BOTULINUM CMP N-GLYCOSIDASE, BCMB
Descriptor:CMP N-GLYCOSIDASE, PHOSPHATE ION
Authors:Sikowitz, M.D., Cooper, L.E., Begley, T.P., Kaminski, P.A., Ealick, S.E.
Deposit date:2013-02-27
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Reversal of the substrate specificity of CMP N-glycosidase to dCMP.
Biochemistry, 52, 2013
4KYS
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CLOSTRIDIUM BOTULINUM THIAMINASE I IN COMPLEX WITH THIAMIN
Descriptor:Thiamine pyridinylase I, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CITRIC ACID, ...
Authors:Sikowitz, M.D., Shome, B., Zhang, Y., Begley, T.P., Ealick, S.E.
Deposit date:2013-05-29
Release date:2013-10-30
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture.
Biochemistry, 52, 2013
4MEJ
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CRYSTAL STRUCTURE OF LACTOBACILLUS HELVETICUS PURINE DEOXYRIBOSYL TRANSFERASE (PDT) WITH THE TRICYCLIC PURINE 8,9-DIHYDRO-9-OXOIMIDAZO[2,1-B]PURINE (N2,3-ETHENOGUANINE)
Descriptor:Nucleoside deoxyribosyltransferase, SULFATE ION, 3H-imidazo[2,1-b]purin-4(5H)-one
Authors:Paul, D., Seckute, J., Ealick, S.E.
Deposit date:2013-08-26
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glycosylation of a tricyclic purine analog at alternative sites by nucleoside 2 -deoxyribosyltransferases
Plos One, 2014