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3MYU
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MYCOPLASMA GENITALIUM MG289
Descriptor:High affinity transport system protein p37, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION
Authors:Sippel, K.H., Boehlein, S.K., Govindasamy, L., Namiki, K., Satai, Y., Quirit, J.G., Agbandje-McKenna, M., Goodison, S., Rosser, C.J., Sankaran, B., McKenna, R.
Deposit date:2010-05-11
Release date:2010-10-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
3EKI
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STRUCTURAL INSIGHTS OF THE MYCOPLASMA HYORHINIS PROTEIN MH-P37: A PUTATIVE THIAMINE PYROPHOSPHATE TRANSPORTER
Descriptor:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, GLYCEROL, ...
Authors:Sippel, K.H., Robbins, A.H., Reutzel, R., McKenna, R.
Deposit date:2008-09-19
Release date:2009-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis
J.Bacteriol., 191, 2009
3D8W
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USE OF A CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase II, ZINC ION, 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-05-26
Release date:2009-03-03
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3D9Z
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-05-28
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DAZ
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-05-30
Release date:2009-03-03
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DBU
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-02
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DC3
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-03
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DC9
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-03
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCC
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-03
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCS
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-04
Release date:2009-03-03
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCW
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-04
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DD0
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USE OF CARBONIC ANHYDRASE II, IX ACTIVE-SITE MIMIC, FOR THE PURPOSE OF SCREENING INHIBITORS FOR POSSIBLE ANTI-CANCER PROPERTIES
Descriptor:Carbonic anhydrase 2, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide
Authors:Genis, C., Sippel, K.H., Case, N., Govindasamy, L., Agbandje-Mckenna, M., Mckenna, R.
Deposit date:2008-06-04
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3E78
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
Descriptor:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, CALCIUM ION, ...
Authors:Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
Deposit date:2008-08-18
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3E79
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
Descriptor:High affinity transport system protein p37, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, THIAMINE DIPHOSPHATE, ...
Authors:Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
Deposit date:2008-08-18
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3OIK
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3,17-O,O-BIS-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIL
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIM
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HUMAN CARBONIC ANHYDRASE II BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-19
Release date:2011-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OKU
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HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH 2-ETHYLESTRONE-3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-25
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OKV
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HUMAN CARBONIC ANHYDRASE II A65S, N67Q (CA IX MIMIC) BOUND WITH 2-ETHYLESTRONE 3-O-SULFAMATE
Descriptor:Carbonic anhydrase 2, ZINC ION, (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, ...
Authors:Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
Deposit date:2010-08-25
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011