6H5Q
 
 | | Cryo-EM structure of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to polyA RNA hexamers. | | Descriptor: | Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3') | | Authors: | Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M. | | Deposit date: | 2018-07-25 | | Release date: | 2019-03-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6H5S
 | | Cryo-EM map of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to viral genomic 5-prime RNA hexamers. | | Descriptor: | Nucleocapsid, RNA (5'-R(*AP*CP*CP*AP*GP*A)-3') | | Authors: | Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J.P, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M. | | Deposit date: | 2018-07-25 | | Release date: | 2019-06-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6RBK
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6RAO
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6RC8
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6RBN
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6RAP
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6RGL
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6I2N
 | | Helical RNA-bound Hantaan virus nucleocapsid | | Descriptor: | Nucleoprotein, RNA (5'-R(P*UP*UP*U)-3') | | Authors: | Arragain, B, Reguera, J, Desfosses, A, Gutsche, I, Schoehn, G, Malet, H. | | Deposit date: | 2018-11-01 | | Release date: | 2019-01-23 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
Elife, 8, 2019
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7P9B
 | | Providencia stuartii Arginine decarboxylase (Adc), decamer structure | | Descriptor: | Biodegradative arginine decarboxylase | | Authors: | Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I. | | Deposit date: | 2021-07-26 | | Release date: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
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8QBF
 | | Compact state - Pil1 dimer with lipid headgroups fitted in native eisosome lattice bound to plasma membrane microdomain | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PHOSPHOSERINE, Sphingolipid long chain base-responsive protein PIL1 | | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | | Deposit date: | 2023-08-24 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
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8QBD
 | | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol, PI(4,5)P2 35:20:20:15:10) | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sphingolipid long chain base-responsive protein PIL1 | | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | | Deposit date: | 2023-08-24 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
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8QBG
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8QBE
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4UFT
 | | Structure of the helical Measles virus nucleocapsid | | Descriptor: | 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN | | Authors: | Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G. | | Deposit date: | 2015-03-19 | | Release date: | 2015-04-29 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid.
Science, 348, 2015
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5AHV
 | | Cryo-EM structure of helical ANTH and ENTH tubules on PI(4,5)P2-containing membranes | | Descriptor: | ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2, ENTH DOMAIN OF EPSIN ENT1 | | Authors: | Skruzny, M, Desfosses, A, Prinz, S, Dodonova, S.O, Gieras, A, Uetrecht, C, Jakobi, A.J, Abella, M, Hagen, W.J.H, Schulz, J, Meijers, R, Rybin, V, Briggs, J.A.G, Sachse, C, Kaksonen, M. | | Deposit date: | 2015-02-10 | | Release date: | 2015-05-06 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (13.6 Å) | | Cite: | An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
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8QBB
 | | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10) | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Sphingolipid long chain base-responsive protein PIL1 | | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | | Deposit date: | 2023-08-24 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
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8QB9
 | | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30) | | Descriptor: | Sphingolipid long chain base-responsive protein PIL1 | | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | | Deposit date: | 2023-08-24 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
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6YN6
 | | Inducible lysine decarboxylase LdcI stacks, pH 5.7 | | Descriptor: | Inducible lysine decarboxylase | | Authors: | Felix, J, Jessop, M, Desfosses, A, Effantin, G, Gutsche, I. | | Deposit date: | 2020-04-10 | | Release date: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Supramolecular assembly of the Escherichia coli LdcI upon acid stress.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6YN5
 | | Inducible lysine decarboxylase LdcI decamer, pH 7.0 | | Descriptor: | Inducible lysine decarboxylase | | Authors: | Jessop, M, Felix, J, Desfosses, A, Effantin, G, Gutsche, I. | | Deposit date: | 2020-04-10 | | Release date: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Supramolecular assembly of the Escherichia coli LdcI upon acid stress.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7PK6
 | | Providencia stuartii Arginine decarboxylase (Adc), stack structure | | Descriptor: | Biodegradative arginine decarboxylase | | Authors: | Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I. | | Deposit date: | 2021-08-25 | | Release date: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (2.15 Å) | | Cite: | Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
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7PQH
 | | Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains). | | Descriptor: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8 | | Authors: | Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R. | | Deposit date: | 2021-09-17 | | Release date: | 2023-01-18 | | Last modified: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | EGOC inhibits TOROID polymerization by structurally activating TORC1.
Nat.Struct.Mol.Biol., 30, 2023
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7ZCH
 | | CHMP2A-CHMP3 heterodimer (410 Angstrom diameter) | | Descriptor: | Charged multivesicular body protein 2a, Charged multivesicular body protein 3 | | Authors: | Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. | | Deposit date: | 2022-03-28 | | Release date: | 2023-01-18 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
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7ZCG
 | | CHMP2A-CHMP3 heterodimer (430 Angstrom diameter) | | Descriptor: | Charged multivesicular body protein 2a, Charged multivesicular body protein 3 | | Authors: | Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W. | | Deposit date: | 2022-03-28 | | Release date: | 2023-01-18 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
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8ALY
 | | Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant) | | Descriptor: | Poly [ADP-ribose] polymerase tankyrase-2, ZINC ION | | Authors: | Mariotti, L, Inian, O, Desfosses, A, Beuron, F, Morris, E.P, Guettler, S. | | Deposit date: | 2022-08-01 | | Release date: | 2022-11-16 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structural basis of tankyrase activation by polymerization.
Nature, 612, 2022
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