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6H5Q
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BU of 6h5q by Molmil
Cryo-EM structure of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to polyA RNA hexamers.
Descriptor: Nucleocapsid, RNA (5'-R(*AP*AP*AP*AP*AP*A)-3')
Authors:Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M.
Deposit date:2018-07-25
Release date:2019-03-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
6H5S
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BU of 6h5s by Molmil
Cryo-EM map of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to viral genomic 5-prime RNA hexamers.
Descriptor: Nucleocapsid, RNA (5'-R(*AP*CP*CP*AP*GP*A)-3')
Authors:Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J.P, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M.
Deposit date:2018-07-25
Release date:2019-06-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
6RBK
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BU of 6rbk by Molmil
Cryo-EM structure of the anti-feeding prophage (AFP) baseplate in extended state, 3-fold symmetrised
Descriptor: Afp7, Afp8
Authors:Desfosses, A.
Deposit date:2019-04-10
Release date:2019-04-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6RAO
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BU of 6rao by Molmil
Cryo-EM structure of the anti-feeding prophage (AFP) baseplate, 6-fold symmetrised
Descriptor: Afp1, Afp11, Afp12, ...
Authors:Desfosses, A.
Deposit date:2019-04-06
Release date:2019-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6RC8
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BU of 6rc8 by Molmil
Cryo-EM structure of the anti-feeding prophage (AFP) helical sheath in contracted state
Descriptor: Afp2, Afp3
Authors:Desfosses, A.
Deposit date:2019-04-11
Release date:2019-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6RBN
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BU of 6rbn by Molmil
Cryo-EM structure of the anti-feeding prophage (AFP) helical sheath-tube complex in extended state
Descriptor: Afp1, Afp2, Afp3
Authors:Desfosses, A.
Deposit date:2019-04-11
Release date:2019-04-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6RAP
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BU of 6rap by Molmil
Cryo-EM structure of the anti-feeding prophage cap (AFP tube terminating cap)
Descriptor: Afp1, Afp16, Afp2, ...
Authors:Desfosses, A.
Deposit date:2019-04-07
Release date:2019-04-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6RGL
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BU of 6rgl by Molmil
Cryo-EM structure of the anti-feeding prophage (AFP) baseplate in contracted state
Descriptor: Afp2, Afp3, Afp4
Authors:Desfosses, A.
Deposit date:2019-04-16
Release date:2019-04-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Atomic structures of an entire contractile injection system in both the extended and contracted states.
Nat Microbiol, 4, 2019
6I2N
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BU of 6i2n by Molmil
Helical RNA-bound Hantaan virus nucleocapsid
Descriptor: Nucleoprotein, RNA (5'-R(P*UP*UP*U)-3')
Authors:Arragain, B, Reguera, J, Desfosses, A, Gutsche, I, Schoehn, G, Malet, H.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
Elife, 8, 2019
7P9B
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BU of 7p9b by Molmil
Providencia stuartii Arginine decarboxylase (Adc), decamer structure
Descriptor: Biodegradative arginine decarboxylase
Authors:Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I.
Deposit date:2021-07-26
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
8QBF
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BU of 8qbf by Molmil
Compact state - Pil1 dimer with lipid headgroups fitted in native eisosome lattice bound to plasma membrane microdomain
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PHOSPHOSERINE, Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
8QBD
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BU of 8qbd by Molmil
Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol, PI(4,5)P2 35:20:20:15:10)
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
8QBG
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BU of 8qbg by Molmil
Stretched state - Pil1 in native eisosome lattice bound to plasma membrane microdomain
Descriptor: Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
8QBE
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BU of 8qbe by Molmil
Compact state - Pil1 in native eisosome lattice bound to plasma membrane microdomain
Descriptor: Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
4UFT
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BU of 4uft by Molmil
Structure of the helical Measles virus nucleocapsid
Descriptor: 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN
Authors:Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G.
Deposit date:2015-03-19
Release date:2015-04-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid.
Science, 348, 2015
5AHV
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BU of 5ahv by Molmil
Cryo-EM structure of helical ANTH and ENTH tubules on PI(4,5)P2-containing membranes
Descriptor: ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2, ENTH DOMAIN OF EPSIN ENT1
Authors:Skruzny, M, Desfosses, A, Prinz, S, Dodonova, S.O, Gieras, A, Uetrecht, C, Jakobi, A.J, Abella, M, Hagen, W.J.H, Schulz, J, Meijers, R, Rybin, V, Briggs, J.A.G, Sachse, C, Kaksonen, M.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
8QBB
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BU of 8qbb by Molmil
Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10)
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
8QB9
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BU of 8qb9 by Molmil
Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30)
Descriptor: Sphingolipid long chain base-responsive protein PIL1
Authors:Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J.
Deposit date:2023-08-24
Release date:2024-07-24
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.
Nature, 632, 2024
6YN6
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BU of 6yn6 by Molmil
Inducible lysine decarboxylase LdcI stacks, pH 5.7
Descriptor: Inducible lysine decarboxylase
Authors:Felix, J, Jessop, M, Desfosses, A, Effantin, G, Gutsche, I.
Deposit date:2020-04-10
Release date:2021-01-13
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Supramolecular assembly of the Escherichia coli LdcI upon acid stress.
Proc.Natl.Acad.Sci.USA, 118, 2021
6YN5
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BU of 6yn5 by Molmil
Inducible lysine decarboxylase LdcI decamer, pH 7.0
Descriptor: Inducible lysine decarboxylase
Authors:Jessop, M, Felix, J, Desfosses, A, Effantin, G, Gutsche, I.
Deposit date:2020-04-10
Release date:2021-01-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Supramolecular assembly of the Escherichia coli LdcI upon acid stress.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PK6
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BU of 7pk6 by Molmil
Providencia stuartii Arginine decarboxylase (Adc), stack structure
Descriptor: Biodegradative arginine decarboxylase
Authors:Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I.
Deposit date:2021-08-25
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation.
Commun Biol, 5, 2022
7PQH
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BU of 7pqh by Molmil
Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains).
Descriptor: Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8
Authors:Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R.
Deposit date:2021-09-17
Release date:2023-01-18
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:EGOC inhibits TOROID polymerization by structurally activating TORC1.
Nat.Struct.Mol.Biol., 30, 2023
7ZCH
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BU of 7zch by Molmil
CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
Authors:Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
Deposit date:2022-03-28
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
7ZCG
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BU of 7zcg by Molmil
CHMP2A-CHMP3 heterodimer (430 Angstrom diameter)
Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
Authors:Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
Deposit date:2022-03-28
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
8ALY
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BU of 8aly by Molmil
Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant)
Descriptor: Poly [ADP-ribose] polymerase tankyrase-2, ZINC ION
Authors:Mariotti, L, Inian, O, Desfosses, A, Beuron, F, Morris, E.P, Guettler, S.
Deposit date:2022-08-01
Release date:2022-11-16
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural basis of tankyrase activation by polymerization.
Nature, 612, 2022

 

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