Author results

6J17
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ATPASE
Descriptor:ESX-3 secretion system protein EccC3, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Wang, S.H., Li, J., Rao, Z.H.
Deposit date:2018-12-28
Release date:2019-12-04
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:Structural insights into substrate recognition by the type VII secretion system.
Protein Cell, 2019
6J18
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ATPASE
Descriptor:ESX-5 secretion system protein EccC5, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Wang, S.H., Li, J., Rao, Z.H.
Deposit date:2018-12-28
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into substrate recognition by the type VII secretion system.
Protein Cell, 2019
6J19
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ATPASE
Descriptor:ESX-1 secretion system protein EccCb1, ESAT-6-like protein EsxB, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Wang, S.H., Li, J., Rao, Z.H.
Deposit date:2018-12-28
Release date:2019-12-04
Method:X-RAY DIFFRACTION (1.978 Å)
Cite:Structural insights into substrate recognition by the type VII secretion system.
Protein Cell, 2019
6JD4
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ATPASE
Descriptor:ESX-1 secretion system protein EccCb1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Wang, S.H., Li, J., Rao, Z.H.
Deposit date:2019-01-31
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into substrate recognition by the type VII secretion system.
Protein Cell, 2019
6JD5
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ATPASE
Descriptor:ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Wang, S.H., Li, J., Rao, Z.H.
Deposit date:2019-01-31
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into substrate recognition by the type VII secretion system.
Protein Cell, 2019
6L6L
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STRUCTURAL BASIS OF NR4A2 HOMODIMERS BINDING TO SELECTIVE NUR-RESPONSIVE ELEMENTS
Descriptor:Nuclear receptor related 1, DNA (5'-D(*AP*AP*AP*GP*GP*TP*CP*AP*AP*AP*CP*TP*GP*TP*GP*AP*CP*CP*TP*AP*T)-3'), DNA (5'-D(P*TP*AP*TP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*TP*TP*GP*AP*CP*CP*TP*T)-3'), ...
Authors:Jiang, L., Chen, Y.
Deposit date:2019-10-29
Release date:2019-11-20
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.781 Å)
Cite:Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements.
J.Biol.Chem., 2019
6L6Q
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STRUCTURAL BASIS OF NR4A2 HOMODIMERS BINDING TO SELECTIVE NUR-RESPONSIVE ELEMENTS
Descriptor:Nuclear receptor related 1, DNA (5'-D(P*AP*GP*TP*GP*AP*CP*CP*TP*TP*TP*AP*AP*AP*GP*GP*TP*CP*AP*CP*T)-3'), ZINC ION
Authors:Jiang, L., Chen, Y.
Deposit date:2019-10-29
Release date:2019-11-20
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements.
J.Biol.Chem., 2019
6KZ8
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CRYSTAL STRUCTURE OF PLANT PHOSPHOLIPASE D ALPHA COMLEX WITH PHOSPHATIDIC ACID
Descriptor:Phospholipase D alpha 1, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, CALCIUM ION
Authors:Li, J.X., Yu, F., Zhang, P.
Deposit date:2019-09-23
Release date:2019-11-13
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 2019
6O3E
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MOUSE AE-CATENIN 82-883
Descriptor:Catenin alpha-1
Authors:Pokutta, S., Weis, W.I.
Deposit date:2019-02-26
Release date:2019-11-13
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling.
Sci Rep, 9, 2019
6J04
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CRYSTAL STRUCTURE OF FULL LENGTH HUMAN LC3B DELTA G120 MUTANT (2_125)
Descriptor:Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
Authors:Ding, Y., Lu, B.X., Wang, Z.Y.
Deposit date:2018-12-21
Release date:2019-11-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds
Nature, 575, 2019
6KZ9
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CRYSTAL STRUCTURE OF PLANT PHOSPHOLIPASE D ALPHA
Descriptor:Phospholipase D alpha 1, CALCIUM ION
Authors:Li, J.X., Yu, F., Zhang, P.
Deposit date:2019-09-23
Release date:2019-10-30
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 2019
6IM6
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-22
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMB
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X., Su, H., Xu, Y.
Deposit date:2018-10-22
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMD
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X., Su, H., Xu, Y.
Deposit date:2018-10-22
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMI
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, MAGNESIUM ION, ZINC ION, ...
Authors:Zhang, X., Su, H., Xu, Y.
Deposit date:2018-10-23
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMO
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-23
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMR
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-23
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IMT
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-23
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.483 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IND
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, (1S)-6,7-dimethoxy-1-[2-(6-methyl-1H-indol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-24
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.872 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6INK
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-25
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6INM
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CRYSTAL STRUCTURE OF PDE4D COMPLEXED WITH A NOVEL INHIBITOR
Descriptor:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
Authors:Zhang, X.L., Su, H.X., Xu, Y.C.
Deposit date:2018-10-26
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
6IS8
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CRYSTAL STRUCTURE OF ZMMOC1 D115N MUTANT IN COMPLEX WITH HOLLIDAY JUNCTION
Descriptor:Monokaryotic chloroplast 1, DNA (33-MER), MAGNESIUM ION, ...
Authors:Lin, Z., Lin, H., Zhang, D., Yuan, C.
Deposit date:2018-11-15
Release date:2019-10-23
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6IS9
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CRYSTAL STRUCTURE OF ZMMOC1
Descriptor:Monokaryotic chloroplast 1
Authors:Lin, Z., Lin, H., Zhang, D., Yuan, C.
Deposit date:2018-11-15
Release date:2019-10-23
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6JRF
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CRYSTAL STRUCTURE OF ZMMOC1-HOLLIDAY JUNCTION COMPLEX IN THE PRESENCE OF CALCIUM
Descriptor:Monokaryotic chloroplast 1, DNA (33-MER), CALCIUM ION, ...
Authors:Lin, Z., Lin, H., Zhang, D., Yuan, C.
Deposit date:2019-04-03
Release date:2019-10-23
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6JRG
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CRYSTAL STRUCTURE OF ZMMOC1 H253A MUTANT IN COMPLEX WITH HOLLIDAY JUNCTION
Descriptor:Monokaryotic chloroplast 1, DNA (33-MER), DNA (32-MER), ...
Authors:Lin, Z., Lin, H., Zhang, D., Yuan, C.
Deposit date:2019-04-03
Release date:2019-10-23
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019