1DYW
| Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans | Descriptor: | CYCLOPHILIN 3 | Authors: | Dornan, J, Page, A.P, Taylor, P, Wu, S.Y, Winter, A.D, Husi, H, Walkinshaw, M.D. | Deposit date: | 2000-02-10 | Release date: | 2000-06-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis Elegans J.Biol.Chem., 274, 1999
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1E8K
| Cyclophilin 3 Complexed With Dipeptide Ala-Pro | Descriptor: | ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, PROLINE | Authors: | Wu, S.Y, Dornan, J, Kontopidis, G, Taylor, P, Walkinshaw, M.D. | Deposit date: | 2000-09-25 | Release date: | 2001-09-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The First Direct Determination of a Ligand Binding Constant in Protein Crystals Angew.Chem.Int.Ed.Engl., 40, 2001
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6QU5
| Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb12 | Descriptor: | 1-[(3,4-dichlorophenyl)methyl]imidazole, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | Authors: | McNae, I.W, Dornan, J, Walkinshaw, M.D. | Deposit date: | 2019-02-26 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice. Nat Commun, 12, 2021
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6QU3
| Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb360 | Descriptor: | 1-[(3,4-dichlorophenyl)methyl]-7~{H}-pyrrolo[3,2-c]pyridin-4-one, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | Authors: | McNae, I.W, Dornan, J, Walkinshaw, M.D. | Deposit date: | 2019-02-26 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice. Nat Commun, 12, 2021
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6QU4
| Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb405 | Descriptor: | 1-[(3,4-dichlorophenyl)methyl]-5-[2-(dimethylamino)ethyl]pyrrolo[3,2-c]pyridin-4-one, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | Authors: | McNae, I.W, Dornan, J, Walkinshaw, M.D. | Deposit date: | 2019-02-26 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice. Nat Commun, 12, 2021
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1IHG
| Bovine Cyclophilin 40, monoclinic form | Descriptor: | Cyclophilin 40, GLYCEROL | Authors: | Taylor, P, Dornan, J, Carrello, A, Minchin, R.F, Ratajczak, T, Walkinshaw, M.D. | Deposit date: | 2001-04-19 | Release date: | 2001-05-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Two structures of cyclophilin 40: folding and fidelity in the TPR domains. Structure, 9, 2001
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1IIP
| Bovine Cyclophilin 40, Tetragonal Form | Descriptor: | Cyclophilin 40, GLYCEROL | Authors: | Taylor, P, Dornan, J, Carrello, A, Minchin, R.F, Ratajczak, T, Walkinshaw, M.D. | Deposit date: | 2001-04-24 | Release date: | 2001-05-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two structures of cyclophilin 40: folding and fidelity in the TPR domains. Structure, 9, 2001
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1E3B
| CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3 | Descriptor: | CYCLOPHILIN 3, GOLD ION, TRIETHYLPHOSPHANE | Authors: | Zou, J, Taylor, P, Dornan, J, Robinson, S.P, Walkinshaw, M.D, Sadler, P.J. | Deposit date: | 2000-06-08 | Release date: | 2000-10-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine Angew.Chem.Int.Ed.Engl., 39, 2000
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4U7B
| Crystal structure of a pre-cleavage Mos1 transpososome | Descriptor: | DNA (25-MER), DNA (31-MER), Mariner Mos1 transposase, ... | Authors: | Richardson, J.M. | Deposit date: | 2014-07-30 | Release date: | 2015-02-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structural role of the flanking DNA in mariner transposon excision. Nucleic Acids Res., 43, 2015
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4N1S
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4N1O
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4N1P
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4N1N
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4N1R
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4N1Q
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