Author results

6QD7
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EM STRUCTURE OF A EBOV-GP BOUND TO 3T0331 NEUTRALIZING ANTIBODY
Descriptor:Light chain, Heavy chain, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, ...
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV.
Nat. Med., 2019
6QD8
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EM STRUCTURE OF A EBOV-GP BOUND TO 4M0368 NEUTRALIZING ANTIBODY
Descriptor:Light chain, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, Envelope glycoprotein, ...
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
6QCU
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CRYSTAL STRUCTURE OF A FAB PORTION OF THE ANTI EBOV 3T0331 ANTIBODY
Descriptor:Light chain, Heavy chain, SULFATE ION
Authors:Diskin, R., Cohen-Dvashi, H.
Deposit date:2018-12-31
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
6GEZ
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THE STRUCTURE OF TWITCH-2B N532F
Descriptor:Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein, CALCIUM ION, FORMIC ACID
Authors:Trigo Mourino, P., Paulat, M., Thestrup, T., Griesbeck, O., Griesinger, C., Becker, S.
Deposit date:2018-04-27
Release date:2019-08-21
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Dynamic tuning of FRET in a green fluorescent protein biosensor.
Sci Adv, 5, 2019
6GEL
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THE STRUCTURE OF TWITCH-2B
Descriptor:Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein, CALCIUM ION, GLYCEROL, ...
Authors:Trigo Mourino, P., Paulat, M., Thestrup, T., Griesbeck, O., Griesinger, C., Becker, S.
Deposit date:2018-04-26
Release date:2019-08-21
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Dynamic tuning of FRET in a green fluorescent protein biosensor.
Sci Adv, 5, 2019
6FCG
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CRYSTAL STRUCTURE OF AN ENDO-LAMINARINASE FROM FORMOSA HEL1_33_131
Descriptor:Glycoside hydrolase, GH17 family, CALCIUM ION
Authors:Becker, S., Robb, C.S., Hehemann, J.H.
Deposit date:2017-12-20
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Adaptive mechanisms that provide competitive advantages to marine bacteroidetes during microalgal blooms.
ISME J, 12, 2018
6EHL
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MODEL OF THE EBOLA VIRUS NUCLEOPROTEIN IN RECOMBINANT NUCLEOCAPSID-LIKE ASSEMBLIES
Descriptor:Nucleoprotein
Authors:Wan, W., Kolesnikova, L., Clarke, M., Koehler, A., Noda, T., Becker, S., Briggs, J.A.G.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
6EHM
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MODEL OF THE EBOLA VIRUS NUCLEOCAPSID SUBUNIT FROM RECOMBINANT VIRUS-LIKE PARTICLES
Descriptor:Nucleoprotein, Membrane-associated protein VP24
Authors:Wan, W., Kolesnikova, L., Clarke, M., Koehler, A., Noda, T., Becker, S., Briggs, J.A.G.
Deposit date:2017-09-13
Release date:2017-11-08
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
5NWX
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Deposit date:2017-05-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5NWM
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Becker, S., Griesinger, C.
Deposit date:2017-05-06
Release date:2017-12-06
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5JDP
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E73V MUTANT OF THE HUMAN VOLTAGE-DEPENDENT ANION CHANNEL
Descriptor:Voltage-dependent anion-selective channel protein 1
Authors:Jaremko, M., Jaremko, L., Villinger, S., Schmidt, C., Giller, K., Griesinger, C., Becker, S., Zweckstetter, M.
Deposit date:2016-04-17
Release date:2016-08-10
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
Angew.Chem.Int.Ed.Engl., 55, 2016
5FQ1
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STRUCTURE OF THE CYTOPLASMIC PAS DOMAIN OF THE GEOBACILLUS THERMODENITRIFICANS HISTIDINE KINASE CITA
Descriptor:HISTIDINE KINASE, GLYCEROL, PHOSPHATE ION
Authors:Schomburg, B., Giller, K., Becker, S.
Deposit date:2015-12-03
Release date:2017-01-11
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Cryogenic optical localization provides 3D protein structure data with Angstrom resolution.
Nat. Methods, 14, 2017
2N7H
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HYBRID STRUCTURE OF THE TYPE 1 PILUS OF UROPATHOGENIC E.COLI
Descriptor:FimA
Authors:Habenstein, B., Loquet, A., Giller, K., Vasa, S., Becker, S., Habeck, M., Lange, A.
Deposit date:2015-09-11
Release date:2015-09-23
Last modified:2015-10-14
Method:SOLID-STATE NMR
Cite:Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli.
Angew.Chem.Int.Ed.Engl., 54, 2015
2N64
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NMR STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85
Descriptor:SH3 domain-containing kinase-binding protein 1
Authors:Habeck, M., Becker, S., Griesinger, C., Wong, L.E.
Deposit date:2015-08-11
Release date:2016-07-13
Method:SOLUTION NMR
Cite:The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation.
Sci.Signal., 9, 2016
5ABS
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CRYSTAL STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85 IN SPACE GROUP P321
Descriptor:SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1, ZINC ION
Authors:Wong, L., Habeck, M., Griesinger, C., Becker, S.
Deposit date:2015-08-07
Release date:2016-07-13
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Adaptor Protein Cin85 Assembles Intracellular Signaling Clusters for B Cell Activation.
Sci.Signal., 9, 2016
5C58
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A DOUBLE MUTANT OF SERRATIA MARCESCENS HEMOPHORE RECEPTOR HASR IN COMPLEX WITH ITS HEMOPHORE HASA AND HEME
Descriptor:HasR protein, Hemophore HasA, PROTOPORPHYRIN IX CONTAINING FE
Authors:Becker, S., Diederichs, K., Welte, W.
Deposit date:2015-06-19
Release date:2016-06-29
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Binding of HasA by its transmembrane receptor HasR follows a conformational funnel mechanism
To Be Published
2N3D
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ATOMIC STRUCTURE OF THE CYTOSKELETAL BACTOFILIN BACA REVEALED BY SOLID-STATE NMR
Descriptor:Bactofilin A
Authors:Shi, C., Fricke, P., Lin, L., Chevelkov, V., Wegstroth, M., Giller, K., Becker, S., Thanbichler, M., Lange, A.
Deposit date:2015-05-29
Release date:2015-12-16
Last modified:2016-02-03
Method:SOLID-STATE NMR
Cite:Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.
Sci Adv, 1, 2015
4ZG4
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MYOSIN VC PRE-POWERSTROKE
Descriptor:myosin-Vc, MAGNESIUM ION, VANADATE ION, ...
Authors:Ropars, V., Pylypenko, O., Sweeney, L., Houdusse, A.
Deposit date:2015-04-22
Release date:2016-03-23
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Force-producing ADP state of myosin bound to actin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YXR
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CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH INHIBITOR.
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-methyl-2H-indazole
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-27
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4YXS
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CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor:cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N-BENZYL-9H-PURIN-6-AMINE
Authors:Schiffer, A., Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-20
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
2N02
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SOLUTION STRUCTURE OF THE A147T VARIANT OF THE MITOCHONDRIAL TRANSLOCATOR PROTEIN (TSPO) IN COMPLEX WITH PK11195
Descriptor:Translocator protein, N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
Authors:Jaremko, M., Jaremko, L., Giller, K., Becker, S., Zweckstetter, M.
Deposit date:2015-03-04
Release date:2015-06-10
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:Structural Integrity of the A147T Polymorph of Mammalian TSPO.
Chembiochem, 16, 2015
2MY2
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SNU17P-BUD13P STRUCTURE INTERMEDIATE DURING RES COMPLEX ASSEMBLY
Descriptor:U2 snRNP component IST3, Pre-mRNA-splicing factor CWC26
Authors:Wysoczanski, P., Becker, S., Zweckstetter, M.
Deposit date:2015-01-19
Release date:2015-08-12
Method:SOLUTION NMR
Cite:Structures of intermediates during RES complex assembly.
Sci Rep, 5, 2015
2MY3
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SNU17P-PML1P STRUCTURE INTERMEDIATE DURING RES COMPLEX ASSEMBLY
Descriptor:U2 snRNP component IST3, Pre-mRNA leakage protein 1
Authors:Wysoczanski, P., Becker, S., Zweckstetter, M.
Deposit date:2015-01-19
Release date:2015-08-12
Method:SOLUTION NMR
Cite:Structures of intermediates during RES complex assembly.
Sci Rep, 5, 2015
2MSG
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SOLID-STATE NMR STRUCTURE OF UBIQUITIN
Descriptor:Ubiquitin
Authors:Lakomek, N., Habenstein, B., Loquet, A., Shi, C., Giller, K., Wolff, S., Becker, S., Fasshuber, H., Lange, A.
Deposit date:2014-08-04
Release date:2015-02-18
Last modified:2015-05-13
Method:SOLID-STATE NMR
Cite:Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR.
Protein Sci., 24, 2015
4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
Descriptor:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
Authors:Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
Deposit date:2014-05-23
Release date:2014-08-27
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014