2Y2T
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2Y2Y
| Oxidised form of E. coli CsgC | Descriptor: | ACETATE ION, CURLI PRODUCTION PROTEIN CSGC | Authors: | Taylor, J.D, Salgado, P.S, Constable, S.C, Cota, E, Mathews, S.J. | Deposit date: | 2010-12-16 | Release date: | 2011-09-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic Resolution Insights Into Curli Fiber Biogenesis. Structure, 19, 2011
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5COM
| Crystal structure of Uncharacterized Protein Q187F5 from Clostridium difficile 630 | Descriptor: | D(-)-TARTARIC ACID, Putative conjugative transposon protein Tn1549-like, CTn5-Orf2, ... | Authors: | Taylor, J.D, Taylor, G, Matthews, S.J. | Deposit date: | 2015-07-20 | Release date: | 2016-02-03 | Last modified: | 2016-03-02 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide. J.Mol.Biol., 428, 2016
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5CIV
| Sibling Lethal Factor Precursor - DfsB | Descriptor: | Sibling bacteriocin | Authors: | Taylor, J.D, Matthews, S.J. | Deposit date: | 2015-07-13 | Release date: | 2016-02-03 | Last modified: | 2016-03-02 | Method: | X-RAY DIFFRACTION (1.384 Å) | Cite: | Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide. J.Mol.Biol., 428, 2016
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5COF
| Crystal structure of Uncharacterised protein Q1R1X2 from Escherichia coli UTI89 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Taylor, J.D, Hare, S, Matthews, S.J. | Deposit date: | 2015-07-20 | Release date: | 2016-02-03 | Last modified: | 2016-03-02 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide. J.Mol.Biol., 428, 2016
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5COG
| Crystal structure of Yeast IRC4 | Descriptor: | CHLORIDE ION, IRC4, PHOSPHATE ION, ... | Authors: | Taylor, J.D, Matthews, S.J. | Deposit date: | 2015-07-20 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.613 Å) | Cite: | Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide. J.Mol.Biol., 428, 2016
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5CQV
| Crystal structure of uncharacterized protein Q8DWV2 from Streptococcus agalactiae | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Uncharacterized protein | Authors: | Taylor, J.D, Hare, S, Matthews, S.J. | Deposit date: | 2015-07-22 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide. J.Mol.Biol., 428, 2016
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2JYQ
| NMR structure of the apo v-Src SH2 domain | Descriptor: | Tyrosine-protein kinase transforming protein Src | Authors: | Taylor, J.D, Ababou, A, Williams, M.A, Ladbury, J.E. | Deposit date: | 2007-12-17 | Release date: | 2008-06-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design Proteins, 73, 2008
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2N59
| Solution Structure of R. palustris CsgH | Descriptor: | Putative uncharacterized protein CsgH | Authors: | Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J. | Deposit date: | 2015-07-13 | Release date: | 2016-05-11 | Method: | SOLUTION NMR | Cite: | Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. Sci Rep, 6, 2016
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2XSK
| E. coli curli protein CsgC - SeCys | Descriptor: | ACETATE ION, CSGC | Authors: | Salgado, P.S, Taylor, J.D, Cota, E, Matthews, S.J. | Deposit date: | 2010-09-29 | Release date: | 2010-12-29 | Last modified: | 2014-01-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Extending the Usability of the Phasing Power of Diselenide Bonds: Secys Sad Phasing of Csgc Using a Non-Auxotrophic Strain. Acta Crystallogr.,Sect.D, 67, 2011
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2KUB
| Solution structure of the alpha subdomain of the major non-repeat unit of Fap1 fimbriae of Streptococcus parasanguis | Descriptor: | Fimbriae-associated protein Fap1 | Authors: | Ramboarina, S, Garnett, J.A, Bodey, A, Simpson, P, Bardiaux, B, Nilges, M, Matthews, S. | Deposit date: | 2010-02-17 | Release date: | 2010-07-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural insights into serine-rich fimbriae from gram-positive bacteria. J.Biol.Chem., 2010
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5KH4
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5KH2
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5KH5
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2X12
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2Y7O
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2Y7N
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2YLH
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2Y7L
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2Y7M
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4Z2B
| The structure of human PDE12 residues 161-609 in complex with GSK3036342A | Descriptor: | 1,2-ETHANEDIOL, 2',5'-phosphodiesterase 12, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. | Deposit date: | 2015-03-29 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J.Biol.Chem., 290, 2015
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4Z0V
| The structure of human PDE12 residues 161-609 | Descriptor: | 2',5'-phosphodiesterase 12, GLYCEROL, MAGNESIUM ION | Authors: | Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. | Deposit date: | 2015-03-26 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J.Biol.Chem., 290, 2015
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4Z2A
| Crystal structure of unglycosylated apo human furin @1.89A | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Furin, ... | Authors: | Gampe, R.T, Pearce, K, Reid, R. | Deposit date: | 2015-03-29 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | BacMam production and crystal structure of nonglycosylated apo human furin at 1.89A resolution Acta Crystallogr.,Sect.F, 2019
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4G34
| Crystal Structure of GSK6924 Bound to PERK (R587-R1092, delete A660-T867) at 2.70 A Resolution | Descriptor: | 1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydro-1H-indol-1-yl]-2-phenylethanone, Eukaryotic translation initiation factor 2-alpha kinase 3 | Authors: | Gampe, R.T, Axten, J.M. | Deposit date: | 2012-07-13 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
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4G31
| Crystal Structure of GSK6414 Bound to PERK (R587-R1092, delete A660-T867) at 2.28 A Resolution | Descriptor: | 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone, Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL | Authors: | Gampe, R.T, Axten, J.M. | Deposit date: | 2012-07-13 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 55, 2012
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