Author results

4E94
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CRYSTAL STRUCTURE OF MCCF-LIKE PROTEIN FROM STREPTOCOCCUS PNEUMONIAE
分子名称:MccC family protein, SULFATE ION, GLYCEROL
著者Nocek, B., Tikhonov, A., Kwon, K., Severinov, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-03-20
公開日2012-05-09
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Crystal structure of MccF-like protein from Streptococcus pneumoniae
TO BE PUBLISHED
5W4K
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH KLEBSAZOLICIN AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.7A RESOLUTION
分子名称:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
著者Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.
登録日2017-06-12
公開日2017-08-30
最終更新日2019-07-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
5UI6
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SOLUTION NMR STRUCTURE OF LASSO PEPTIDE ACINETODIN
分子名称:Acinetodin
著者Bushin, L.B., Metelev, M., Severinov, K., Seyedsayamdost, M.R.
登録日2017-01-12
公開日2017-02-08
最終更新日2017-03-29
実験手法SOLUTION NMR
主引用文献Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
5UI7
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SOLUTION NMR STRUCTURE OF LASSO PEPTIDE KLEBSIDIN
分子名称:Klebsidin
著者Bushin, L.B., Metelev, M., Severinov, K., Seyedsayamdost, M.R.
登録日2017-01-13
公開日2017-02-08
最終更新日2017-03-29
実験手法SOLUTION NMR
主引用文献Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
1YNN
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TAQ RNA POLYMERASE-RIFAMPICIN COMPLEX
分子名称:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
登録日2005-01-24
公開日2005-03-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1HQM
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CRYSTAL STRUCTURE OF THERMUS AQUATICUS CORE RNA POLYMERASE-INCLUDES COMPLETE STRUCTURE WITH SIDE-CHAINS (EXCEPT FOR DISORDERED REGIONS)-FURTHER REFINED FROM ORIGINAL DEPOSITION-CONTAINS ADDITIONAL SEQUENCE INFORMATION
分子名称:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Minakhin, L., Bhagat, S., Brunning, A., Campbell, E.A., Darst, S.A., Ebright, R.H., Severinov, K.
登録日2000-12-18
公開日2001-02-07
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc.Natl.Acad.Sci.USA, 98, 2001
1YNJ
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TAQ RNA POLYMERASE-SORANGICIN COMPLEX
分子名称:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
登録日2005-01-24
公開日2005-03-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
2A6H
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC STERPTOLYDIGIN
分子名称:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Temiakov, D., Zenkin, N., Vassylyeva, M.N., Perederina, A., Tahirov, T.H., Savkina, M., Zorov, S., Nikiforov, V., Igarashi, N., Matsugaki, N., Wakatsuki, S., Severinov, K., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-02
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
2MC5
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A BACTERIOPHAGE TRANSCRIPTION REGULATOR INHIBITS BACTERIAL TRANSCRIPTION INITIATION BY -FACTOR DISPLACEMENT
分子名称:45L
著者Liu, B., Shadrin, A., Sheppard, C., Xu, Y., Severinov, K., Matthews, S., Wigneshweraraj, S.
登録日2013-08-14
公開日2014-03-26
最終更新日2014-04-30
実験手法SOLUTION NMR
主引用文献A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
2MC6
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A BACTERIOPHAGE TRANSCRIPTION REGULATOR INHIBITS BACTERIAL TRANSCRIPTION INITIATION BY SIGMA-FACTOR DISPLACEMENT
分子名称:RNA polymerase inhibitor p7, DNA-directed RNA polymerase subunit beta'
著者Liu, B., Shadrin, A., Sheppard, C., Xu, Y., Severinov, K., Matthews, S., Wigneshweraraj, S.
登録日2013-08-15
公開日2014-04-02
最終更新日2014-05-07
実験手法SOLUTION NMR
主引用文献A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
2MW3
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SOLUTION NMR STRUCTURE OF THE LASSO PEPTIDE STREPTOMONOMICIN
分子名称:Lasso peptide
著者Tietz, J.I., Zhu, L., Mitchell, D.A., Metelev, M., Melby, J.O., Blair, P.M., Livnat, I., Severinov, K.
登録日2014-10-24
公開日2015-01-28
最終更新日2015-03-04
実験手法SOLUTION NMR
主引用文献Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.
Chem.Biol., 22, 2015
3WOD
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RNA POLYMERASE-GP39 COMPLEX
分子名称:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
登録日2013-12-26
公開日2014-03-12
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
3WOE
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CRYSTAL STRUCTURE OF P23-45 GP39 (6-109) BOUND TO THERMUS THERMOPHILUS RNA POLYMERASE BETA-FLAP DOMAIN
分子名称:DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein
著者Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
登録日2013-12-26
公開日2014-03-12
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
3WOF
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CRYSTAL STRUCTURE OF P23-45 GP39 (6-132) BOUND TO THERMUS THERMOPHILUS RNA POLYMERASE BETA-FLAP DOMAIN
分子名称:DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein
著者Tagami, S., Sekine, S., Minakhin, L., Esyunina, D., Akasaka, R., Shirouzu, M., Kulbachinskiy, A., Severinov, K., Yokoyama, S.
登録日2013-12-26
公開日2014-03-12
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
4INJ
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CRYSTAL STRUCTURE OF THE S111A MUTANT OF MEMBER OF MCCF CLADE FROM LISTERIA MONOCYTOGENES EGD-E WITH PRODUCT
分子名称:Lmo1638 protein, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE, MAGNESIUM ION, ...
著者Nocek, B., Tikhonov, A., Severinov, K., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-01-04
公開日2013-02-20
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the S111A mutant of member of MccF clade from Listeria monocytogenes EGD-e with product
To be Published
4JVO
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CRYSTAL STRUCTURE OF THE DOUBLE MUTANT (S112A, H303A) OF B.ANTHRACIS MYCROCINE IMMUNITY PROTEIN (MCCF) WITH ALANYL SULFAMOYL ADENYLATES
分子名称:Microcin immunity protein MccF, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, GLYCEROL
著者Nocek, B., Tikhonov, A., Severinov, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-03-25
公開日2013-06-12
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the double mutant (S112A, H303A) of B.anthracis mycrocine immunity protein (MccF) with alanyl sulfamoyl adenylates
TO BE PUBLISHED
4MI1
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CRYSTAL STRUCTURE OF THE DOUBLE MUTANT (S112A, H303A) OF B.ANTHRACIS MYCROCINE IMMUNITY PROTEIN (MCCF) WITH ASPARTYL SULFAMOYL ADENYLATES
分子名称:Microcin immunity protein MccF, 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, SULFATE ION
著者Nocek, B., Severinov, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-08-30
公開日2014-04-23
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the double mutant (S112A, H303A) of B.anthracis mycrocine immunity protein (MccF) with aspartyl sulfamoyl adenylates
TO BE PUBLISHED
4ZJN
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE G20C PORTAL PROTEIN
分子名称:Portal protein, (4S)-2-METHYL-2,4-PENTANEDIOL
著者Williams, L.S., Turkenburg, J.P., Levdikov, V.M., Minakhin, L., Severinov, K., Antson, A.A.
登録日2015-04-29
公開日2015-05-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of the bacteriophage G20C portal protein
To be published
5F5X
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CRYSTAL STRUCTURE OF S116A BA3275 WITH AMP BOUND
分子名称:MccC family protein Ba3275, ADENOSINE MONOPHOSPHATE
著者Nocek, B., Severinov, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-12-04
公開日2015-12-30
最終更新日2017-02-08
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Crystal structure of Ba3275-AMP complex from Bacillus cereus ATCC 10987
To Be Published
5F9M
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CRYSTAL STRUCTURE OF NATIVE B3275, MEMBER OF MCCF FAMILY OF ENZYMES
分子名称:MccC family protein
著者Nocek, B., Severinov, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-12-09
公開日2015-12-30
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structure of native B3275, member of MccF family of enzymes.
To Be Published
5FCD
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CRYSTAL STRUCTURE OF MCCD PROTEIN
分子名称:UNK-UNK-UNK-MSE-UNK, UNK-UNK-UNK-UNK-MSE-UNK, MccD, ...
著者Nocek, B., Jedrzejczak, R., Anderson, W.F., Severinov, K., Dubiley, S., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-12-15
公開日2015-12-30
最終更新日2017-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of MccD protein.
To Be Published
5FD8
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CRYSTAL STRUCTURE OF MCCF-LIKE PROTEIN (BA_5613) IN COMPLEX WITH ASA (ALANYL SULFAMOYL ADENYLATES)
分子名称:LD-carboxypeptidase family protein, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE
著者Nocek, B., Severinov, K., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-12-15
公開日2015-12-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of MccF-like Protein (BA_5613) in complex with ASA ( (alanyl sulfamoyl adenylates)
To Be Published
5K99
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CRYSTAL STRUCTURE OF MICROCIN IMMUNITY PROTEIN MCCF FROM BACILLUS ANTHRACIS IN COMPLEX WITH MCC
分子名称:Microcin C7 self-immunity protein mccF, Microcin C
著者Nocek, B., Kulikovsky, A., Severinov, K., Dubiley, S., Joachimiak, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-31
公開日2017-03-22
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of microcin immunity protein MccF from Bacillus anthracis in complex with McC
To Be Published
5NJ5
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH PHOSPHATE BOUND
分子名称:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
著者Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
登録日2017-03-28
公開日2017-10-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJ9
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH DRVY ANGIOTENSIN FRAGMENT BOUND
分子名称:Metalloprotease TldD, Metalloprotease PmbA, ASP-ARG-VAL-TYR, ...
著者Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
登録日2017-03-28
公開日2017-10-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017