Author results

4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2013-11-18
公開日2013-12-25
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
1H3I
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CRYSTAL STRUCTURE OF THE HISTONE METHYLTRANSFERASE SET7/9
分子名称:HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION
著者Wilson, J.R., Jing, C., Walker, P.A., Martin, S.R., Howell, S.A., Blackburn, G.M., Gamblin, S.J., Xiao, B.
登録日2002-09-04
公開日2002-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
Cell(Cambridge,Mass.), 111, 2002
1MXE
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STRUCTURE OF THE COMPLEX OF CALMODULIN WITH THE TARGET SEQUENCE OF CAMKI
分子名称:Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I, CALCIUM ION
著者Clapperton, J.A., Martin, S.R., Smerdon, S.J., Gamblin, S.J., Bayley, P.M.
登録日2002-10-02
公開日2002-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the Complex of Calmodulin with the Target Sequence of Calmodulin-Dependent Protein Kinase I: Studies of the Kinase Activation Mechanism
Biochemistry, 41, 2002
1RGW
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SOLUTION STRUCTURE OF ZASP'S PDZ DOMAIN
分子名称:ZASP protein
著者Au, Y., Atkinson, R.A., Pallavicini, A., Joseph, C., Martin, S.R., Muskett, F.W., Guerrini, R., Faulkner, G., Pastore, A.
登録日2003-11-13
公開日2004-04-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy.
Structure, 12, 2004
2ASB
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STRUCTURE OF A MYCOBACTERIUM TUBERCULOSIS NUSA-RNA COMPLEX
分子名称:ribosomal RNA (5'- GAACUCAAUAG -3'), Transcription elongation protein nusA
著者Beuth, B., Pennell, S., Arnvig, K.B., Martin, S.R., Taylor, I.A.
登録日2005-08-23
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
2ATW
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STRUCTURE OF A MYCOBACTERIUM TUBERCULOSIS NUSA-RNA COMPLEX
分子名称:ribosomal RNA (5'- AGAACUCAAUAG -3'), Transcription elongation protein nusA
著者Beuth, B., Pennell, S., Arnvig, K.B., Martin, S.R., Taylor, I.A.
登録日2005-08-26
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
2BF0
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CRYSTAL STRUCTURE OF THE RPR OF PCF11
分子名称:PCF11, CALCIUM ION
著者Noble, C.G., Hollingworth, D., Martin, S.R., Adeniran, V.E., Smerdon, S.J., Kelly, G., Taylor, I.A., Ramos, A.
登録日2004-12-02
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
2BQZ
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
分子名称:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
著者Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
登録日2005-04-28
公開日2005-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-13
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-20
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-23
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2Y8L
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-07
公開日2011-03-16
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-09
公開日2011-03-16
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-17
公開日2011-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YP2
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP3
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP4
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP5
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP7
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP8
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP9
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-29
公開日2012-11-07
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YPG
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HAEMAGGLUTININ OF 1968 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
著者Liu, J., Xiong, X., Haire, L.F., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
登録日2012-10-30
公開日2012-11-07
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CKZ
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N1 NEURAMINIDASE H274Y + ZANAMIVIR
分子名称:Neuraminidase, CALCIUM ION, ZANAMIVIR
著者Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL0
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N1 NEURAMINIDASE H274Y + OSELTAMIVIR
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION
著者Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL2
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N1 NEURAMINIDASE N294S + OSELTAMIVIR
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
著者Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.538 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008