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1G1E
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BU of 1g1e by Molmil
NMR STRUCTURE OF THE HUMAN MAD1 TRANSREPRESSION DOMAIN SID IN COMPLEX WITH MAMMALIAN SIN3A PAH2 DOMAIN
Descriptor: MAD1 PROTEIN, SIN3A
Authors:Brubaker, K, Cowley, S.M, Huang, K, Eisenman, R.N, Radhakrishnan, I.
Deposit date:2000-10-11
Release date:2000-12-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex.
Cell(Cambridge,Mass.), 103, 2000
1M62
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BU of 1m62 by Molmil
Solution structure of the BAG domain from BAG4/SODD
Descriptor: BAG-family molecular chaperone regulator-4
Authors:Briknarova, K, Takayama, S, Homma, S, Baker, K, Cabezas, E, Hoyt, D.W, Li, Z, Satterthwait, A.C, Ely, K.R.
Deposit date:2002-07-11
Release date:2002-07-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:BAG4/SODD protein contains a short BAG domain.
J.Biol.Chem., 277, 2002
2RMS
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BU of 2rms by Molmil
Solution structure of the mSin3A PAH1-SAP25 SID complex
Descriptor: MSin3A-binding protein, Paired amphipathic helix protein Sin3a
Authors:Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I.
Deposit date:2007-11-14
Release date:2008-01-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
J.Mol.Biol., 375, 2007
2RMR
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BU of 2rmr by Molmil
Solution structure of mSin3A PAH1 domain
Descriptor: Paired amphipathic helix protein Sin3a
Authors:Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I.
Deposit date:2007-11-14
Release date:2008-01-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
J.Mol.Biol., 375, 2007
6SRR
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BU of 6srr by Molmil
Crystal structure of human SHIP2 catalytic domain
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Authors:Whitfield, H, Brearley, C.A, Hemmings, A.M.
Deposit date:2019-09-05
Release date:2021-01-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.
J.Med.Chem., 64, 2021
6SQU
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BU of 6squ by Molmil
Crystal structure of human SHIP2 catalytic domain in complex with 1,2,4 Dimer
Descriptor: 5,5'-(ethane-1,2-diylbis(oxy))bis(benzene-5,4,2,1,-tetrayl)hexakisphosphate, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Authors:Whitfield, H, Brearley, C.A, Hemmings, A.M.
Deposit date:2019-09-04
Release date:2021-01-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.
J.Med.Chem., 64, 2021
6FL8
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BU of 6fl8 by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with purpurogallin and ADP
Descriptor: 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
Deposit date:2018-01-25
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
6FJK
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BU of 6fjk by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with myo-IP6 and ADP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
Deposit date:2018-01-22
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.025 Å)
Cite:A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
6FL3
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BU of 6fl3 by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with myo-IP5 and ADP
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Inositol-pentakisphosphate 2-kinase, ...
Authors:Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
Deposit date:2018-01-25
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
6GFG
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BU of 6gfg by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with D-chiro-IP6 and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, D-chiro inositol hexakisphosphate, Inositol-pentakisphosphate 2-kinase, ...
Authors:Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
Deposit date:2018-04-30
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
6GFH
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BU of 6gfh by Molmil
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from A. thaliana in complex with neo-IP5 and ATP
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Whitfield, H.L, Brearley, C.A, Hemmings, A.M.
Deposit date:2018-04-30
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
J. Med. Chem., 61, 2018
5BJT
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BU of 5bjt by Molmil
Crystal structure of human FcRn with a peptide inhibitor at multiple sites
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, peptide inhibitor
Authors:Nienaber, V, Badger, J.
Deposit date:2016-10-23
Release date:2017-03-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7SBI
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BU of 7sbi by Molmil
Tandem diubiquitin-like domain from chicken 2'-5'-oligoadenylate synthetase-like protein
Descriptor: 2'-5' oligoadenylate synthase
Authors:Freitas, B.T, Pegan, S.D.
Deposit date:2021-09-24
Release date:2022-01-12
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Structure and Immune Regulatory Implications of the Ubiquitin-Like Tandem Domain Within an Avian 2'-5' Oligoadenylate Synthetase-Like Protein
Front Immunol, 12, 2022
1S5Q
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BU of 1s5q by Molmil
Solution Structure of Mad1 SID-mSin3A PAH2 Complex
Descriptor: MAD protein, Sin3a protein
Authors:Swanson, K.A, Knoepfler, P.S, Huang, K, Kang, R.S, Cowley, S.M, Laherty, C.D, Eisenman, R.N, Radhakrishnan, I.
Deposit date:2004-01-21
Release date:2004-07-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations.
Nat.Struct.Mol.Biol., 11, 2004

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