1SDN
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3MZF
| Structure of penicillin-binding protein 5 from E. coli: imipenem acyl-enzyme complex | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL | Authors: | Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C. | Deposit date: | 2010-05-12 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity Biochemistry, 49, 2010
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3MZE
| Structure of penicillin-binding protein 5 from E.coli: cefoxitin acyl-enzyme complex | Descriptor: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL | Authors: | Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C. | Deposit date: | 2010-05-12 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity Biochemistry, 49, 2010
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3MZD
| Structure of penicillin-binding protein 5 from E. coli: cloxacillin acyl-enzyme complex | Descriptor: | (2R,4S)-2-[(1S)-1-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolid ine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL | Authors: | Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C. | Deposit date: | 2010-05-12 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity Biochemistry, 49, 2010
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1NZU
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1Z6F
| Crystal structure of penicillin-binding protein 5 from E. coli in complex with a boronic acid inhibitor | Descriptor: | GLYCEROL, N1-[(1R)-1-(DIHYDROXYBORYL)ETHYL]-N2-[(TERT-BUTOXYCARBONYL)-D-GAMMA-GLUTAMYL]-N6-[(BENZYLOXY)CARBONYL-L-LYSINAMIDE, Penicillin-binding protein 5 | Authors: | Nicola, G, Peddi, S, Stefanova, M, Nicholas, R.A, Gutheil, W.G, Davies, C. | Deposit date: | 2005-03-22 | Release date: | 2005-06-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Escherichia coli Penicillin-Binding Protein 5 Bound to a Tripeptide Boronic Acid Inhibitor: A Role for Ser-110 in Deacylation. Biochemistry, 44, 2005
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1NJ4
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2QBX
| EphB2/SNEW Antagonistic Peptide Complex | Descriptor: | Ephrin type-B receptor 2, SULFATE ION, antagonistic peptide | Authors: | Chrencik, J.E, Brooun, A, Recht, M.I, Nicola, G, Pasquale, E.B, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | Deposit date: | 2007-06-18 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. J.Biol.Chem., 282, 2007
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1NZO
| The crystal structure of wild type penicillin-binding protein 5 from E. coli | Descriptor: | BETA-MERCAPTOETHANOL, Penicillin-binding protein 5 | Authors: | Nicholas, R.A, Krings, S, Tomberg, J, Nicola, G, Davies, C. | Deposit date: | 2003-02-19 | Release date: | 2004-01-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex. J.Biol.Chem., 278, 2003
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2JNF
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