7BV7
 
 | | INTS3 complexed with INTS6 | | Descriptor: | Integrator complex subunit 3, Integrator complex subunit 6 | | Authors: | Jia, Y, Bharath, S.R, Song, H. | | Deposit date: | 2020-04-09 | | Release date: | 2021-07-14 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the INTS3/INTS6 complex reveals the functional importance of INTS3 dimerization in DSB repair.
Cell Discov, 7, 2021
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2L5F
 | | Solution structure of the tandem WW domains from HYPA/FBP11 | | Descriptor: | Pre-mRNA-processing factor 40 homolog A | | Authors: | Jiang, Y, Hu, H. | | Deposit date: | 2010-11-01 | | Release date: | 2011-05-11 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Interaction with polyglutamine expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA)
To be Published
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6PPT
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6PQ2
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5X74
 | | The crystal Structure PDE delta in complex with compound (R, R)-1g | | Descriptor: | (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | | Authors: | Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C. | | Deposit date: | 2017-02-23 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
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5X73
 | | The crystal Structure PDE delta in complex with R-p9 | | Descriptor: | (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | | Authors: | Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C. | | Deposit date: | 2017-02-23 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
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6PQM
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6PRQ
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6PRJ
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6PRP
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6PQE
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6PRI
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6PSI
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1LNQ
 | | CRYSTAL STRUCTURE OF MTHK AT 3.3 A | | Descriptor: | CALCIUM ION, POTASSIUM CHANNEL RELATED PROTEIN | | Authors: | Jiang, Y, Lee, A, Chen, J, Cadene, M, Chait, B.T, Mackinnon, R. | | Deposit date: | 2002-05-03 | | Release date: | 2002-06-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
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5EFX
 | | Crystal structure of Rho GTPase regulator | | Descriptor: | Rho guanine nucleotide exchange factor 2 | | Authors: | Jiang, Y, Ouyang, S, Liu, Z.J. | | Deposit date: | 2015-10-26 | | Release date: | 2016-06-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.451 Å) | | Cite: | Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding
Biochem.Biophys.Res.Commun., 471, 2016
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1ORS
 | | X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab | | Descriptor: | 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel | | Authors: | Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2003-03-14 | | Release date: | 2003-05-06 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
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1ORQ
 | | X-ray structure of a voltage-dependent potassium channel in complex with an Fab | | Descriptor: | 6E1 Fab heavy chain, 6E1 Fab light chain, CADMIUM ION, ... | | Authors: | Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2003-03-14 | | Release date: | 2003-05-06 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
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8TEL
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8TEH
 | | Cryo-EM structure of Arabidopsis thaliana Bor1 in lipid nanodiscs | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Boron transporter 1 | | Authors: | Jiang, Y, Jiang, J. | | Deposit date: | 2023-07-06 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structure of borate transporter Bor1 reveals a novel auto-inhibition mechanism for
the SLC4 family
To Be Published
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8TEG
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8TEJ
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8TEM
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8TEI
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8TEN
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1ID1
 | | CRYSTAL STRUCTURE OF THE RCK DOMAIN FROM E.COLI POTASSIUM CHANNEL | | Descriptor: | PUTATIVE POTASSIUM CHANNEL PROTEIN | | Authors: | Jiang, Y, Pico, A, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-04-02 | | Release date: | 2001-04-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.
Neuron, 29, 2001
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