Author results

2APQ
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CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A (H119A-RNASE A) WITH A 10-GLUTAMINE EXPANSION IN THE C-TERMINAL HINGE-LOOP.
Descriptor:Ribonuclease, PHOSPHATE ION
Authors:Sambashivan, S., Liu, Y., Sawaya, M.R., Gingery, M., Eisenberg, D.
Deposit date:2005-08-16
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature, 437, 2005
2FTP
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CRYSTAL STRUCTURE OF HYDROXYMETHYLGLUTARYL-COA LYASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:hydroxymethylglutaryl-CoA lyase, SODIUM ION, GLYCEROL
Authors:Xiao, T., Evdokimova, E., Liu, Y., Kudritska, M., Savchenko, A., Pai, E.F., Edwards, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-01-24
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa
To be Published
2H40
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF UNLIGANDED PDE5
Descriptor:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION
Authors:Wang, H., Liu, Y., Huai, Q., Cai, J., Zoraghi, R., Francis, S.H., Corbin, J.D., Robinson, H., Xin, Z., Lin, G., Ke, H.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
2HWV
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CRYSTAL STRUCTURE OF AN ESSENTIAL RESPONSE REGULATOR DNA BINDING DOMAIN, VICRC IN ENTEROCOCCUS FAECALIS, A MEMBER OF THE YYCF SUBFAMILY.
Descriptor:DNA-binding response regulator VicR, SULFATE ION
Authors:Trinh, C.H., Liu, Y., Phillips, S.E.V., Phillips-Jones, M.K.
Deposit date:2006-08-02
Release date:2007-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the response regulator VicR DNA-binding domain.
Acta Crystallogr.,Sect.D, 63, 2007
2IS9
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STRUCTURE OF YEAST DCN-1
Descriptor:Defective in cullin neddylation protein 1, PLATINUM (II) ION, CHLORIDE ION, ...
Authors:Yang, X., Zhou, J., Sun, L., Wei, Z., Gao, J., Gong, W., Xu, R.M., Rao, Z., Liu, Y.
Deposit date:2006-10-16
Release date:2007-06-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007
2J6W
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R164N MUTANT OF THE RUNX1 RUNT DOMAIN
Descriptor:RUNT-RELATED TRANSCRIPTION FACTOR 1, CHLORIDE ION
Authors:Grembecka, J., Zhe, L., Lukasik, S.M., Liu, Y., Bielnicka, I., Bushweller, J.H., Speck, N.A.
Deposit date:2006-10-04
Release date:2007-10-09
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
J.Mol.Biol., 364, 2006
2JVC
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NMR SOLUTION STRUCTURE OF UBIQUITIN LIKE PROTEIN
Descriptor:ubiquitin_like protein
Authors:Tran, N.B., Liu, Y., Hew, L.C.
Deposit date:2007-09-17
Release date:2008-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of ubiquitin like protein
To be Published
2K6S
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STRUCTURE OF RAB11-FIP2 C-TERMINAL COILED-COIL DOMAIN
Descriptor:Rab11fip2 protein
Authors:Wei, J., Liu, Y., Baleja, J.D.
Deposit date:2008-07-18
Release date:2009-06-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Disorder and structure in the Rab11 binding domain of Rab11 family interacting protein 2.
Biochemistry, 48, 2009
2KBV
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STRUCTURAL AND FUNCTIONAL ANALYSIS OF TM XI OF THE NHE1 ISOFORM OF THE NA+/H+ EXCHANGER
Descriptor:Sodium/hydrogen exchanger 1
Authors:Lee, B.L., Li, X., Liu, Y., Sykes, B.D., Fliegel, L.
Deposit date:2008-12-09
Release date:2009-01-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger
J.Biol.Chem., 284, 2009
2LQ9
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SOLUTION STRUCTURE OF THE K60A MUTANT OF ATOX1
Descriptor:Copper transport protein ATOX1
Authors:Xi, Z., Shi, C., Lai, C., Tian, C., Liu, Y.
Deposit date:2012-02-28
Release date:2013-03-27
Method:SOLUTION NMR
Cite:Solution structure of the K60A mutant of Atox1
To be Published
2N3J
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SOLUTION STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM THE REDOX-SENSITIVE CHAPERONE, HSPB1
Descriptor:Heat shock protein beta-1
Authors:Rajagopal, P., Liu, Y., Shi, L., Klevit, R.E.
Deposit date:2015-06-03
Release date:2015-08-19
Last modified:2015-10-14
Method:SOLUTION NMR
Cite:Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1.
J.Biomol.Nmr, 63, 2015
2O0F
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DOCKING OF THE MODIFIED RF3 X-RAY STRUCTURE INTO CRYO-EM MAP OF E.COLI 70S RIBOSOME BOUND WITH RF3
Descriptor:Peptide chain release factor 3
Authors:Gao, H., Zhou, Z., Rawat, U., Huang, C., Bouakaz, L., Wang, C., Liu, Y., Zavialov, A., Gursky, R., Sanyal, S., Ehrenberg, M., Frank, J., Song, H.
Deposit date:2006-11-27
Release date:2007-07-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
2OIE
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CRYSTAL STRUCTURE OF RS21-C6 CORE SEGMENT RSCUT
Descriptor:RS21-C6, SULFATE ION
Authors:Wu, B., Liu, Y., Zhao, Q., Liao, S., Zhang, J., Bartlam, M., Chen, W., Rao, Z.
Deposit date:2007-01-10
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis
J.Mol.Biol., 367, 2007
2OIG
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CRYSTAL STRUCTURE OF RS21-C6 CORE SEGMENT AND DM5CTP COMPLEX
Descriptor:RS21-C6, 2'-DEOXY-5-METHYLCYTIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE)
Authors:Wu, B., Liu, Y., Zhao, Q., Liao, S., Zhang, J., Bartlam, M., Chen, W., Rao, Z.
Deposit date:2007-01-11
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis
J.Mol.Biol., 367, 2007
2P0K
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CRYSTAL STRUCTURE OF SCMH1
Descriptor:Polycomb protein SCMH1, CHLORIDE ION, PHOSPHATE ION
Authors:Herzanych, N., Senisterra, G., Liu, Y., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of SCMH1
To be Published
2PQW
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CRYSTAL STRUCTURE OF L3MBTL1 IN COMPLEX WITH H4K20ME2 (RESIDUES 17-25), TRIGONAL FORM
Descriptor:Lethal(3)malignant brain tumor-like protein, Histone H4, ACETATE ION
Authors:Allali-Hassani, A., Liu, Y., Herzanych, N., Ouyang, H., Mackenzie, F., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.R., Structural Genomics Consortium (SGC)
Deposit date:2007-05-02
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2RJC
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CRYSTAL STRUCTURE OF L3MBTL1 PROTEIN IN COMPLEX WITH MES
Descriptor:Lethal(3)malignant brain tumor-like protein, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Allali-Hassani, A., Liu, Y., Herzanych, N., Ouyang, H., Mackenzie, F., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.R., Structural Genomics Consortium (SGC)
Deposit date:2007-10-14
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2RJD
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CRYSTAL STRUCTURE OF L3MBTL1 PROTEIN
Descriptor:Lethal(3)malignant brain tumor-like protein
Authors:Allali-Hassani, A., Liu, Y., Herzanych, N., Ouyang, H., Mackenzie, F., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.R., Structural Genomics Consortium (SGC)
Deposit date:2007-10-14
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2RJE
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CRYSTAL STRUCTURE OF L3MBTL1 IN COMPLEX WITH H4K20ME2 (RESIDUES 17-25), ORTHORHOMBIC FORM II
Descriptor:Lethal(3)malignant brain tumor-like protein, Histone H4, CHLORIDE ION
Authors:Allali-Hassani, A., Liu, Y., Herzanych, N., Ouyang, H., Mackenzie, F., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.R., Structural Genomics Consortium (SGC)
Deposit date:2007-10-14
Release date:2007-10-30
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2RJF
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CRYSTAL STRUCTURE OF L3MBTL1 IN COMPLEX WITH H4K20ME2 (RESIDUES 12-30), ORTHORHOMBIC FORM I
Descriptor:Lethal(3)malignant brain tumor-like protein, Histone H4
Authors:Allali-Hassani, A., Liu, Y., Herzanych, N., Ouyang, H., Mackenzie, F., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J.R., Structural Genomics Consortium (SGC)
Deposit date:2007-10-14
Release date:2007-10-30
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2WXF
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THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH PIK-39.
Descriptor:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE
Authors:Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
Deposit date:2009-11-09
Release date:2010-01-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
2WXG
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THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH SW13.
Descriptor:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, 2-{[4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one
Authors:Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
Deposit date:2009-11-09
Release date:2010-01-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
2WXH
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THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH SW14.
Descriptor:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, 2-{[4-amino-3-(3-fluoro-4-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one
Authors:Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
Deposit date:2009-11-09
Release date:2010-01-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
2WXI
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THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH SW30.
Descriptor:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, 2-{[4-amino-3-(3-hydroxyprop-1-yn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GLYCEROL
Authors:Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
Deposit date:2009-11-09
Release date:2010-01-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
2WXJ
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THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH INK654.
Descriptor:PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM, N-[6-(4-amino-1-{[2-(4-methylpiperazin-1-yl)quinolin-3-yl]methyl}-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzothiazol-2-yl]acetamide
Authors:Berndt, A., Miller, S., Williams, O., Lee, D.D., Houseman, B.T., Pacold, J.I., Gorrec, F., Hon, W.-C., Liu, Y., Rommel, C., Gaillard, P., Ruckle, T., Schwarz, M.K., Shokat, K.M., Shaw, J.P., Williams, R.L.
Deposit date:2009-11-09
Release date:2010-01-12
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010