5FKW
| cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon) | 分子名称: | DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2015-10-20 | 公開日 | 2015-11-25 | 最終更新日 | 2019-02-27 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
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5FXT
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5FKV
| cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex) | 分子名称: | DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ... | 著者 | Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. | 登録日 | 2015-10-20 | 公開日 | 2015-11-25 | 最終更新日 | 2019-02-27 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
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8DKD
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5FVE
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8DK9
| Sliding-clamp-DinX peptide | 分子名称: | ACETYL GROUP, AMINO GROUP, Beta sliding clamp, ... | 著者 | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | 登録日 | 2022-07-05 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Interaction of sliding clamp with mycobacterial polymerases To Be Published
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8DJQ
| Sliding-clamp-DnaE1 peptide | 分子名称: | ACETYL GROUP, AMINO GROUP, Beta sliding clamp, ... | 著者 | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | 登録日 | 2022-07-01 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Interaction of the sliding clamp with mycobacterial polymerases To Be Published
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5G4Q
| H.pylori Beta clamp in complex with 5-chloroisatin | 分子名称: | 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA | 著者 | Pandey, P, Gourinath, S. | 登録日 | 2016-05-16 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
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5G48
| H.pylori Beta clamp in complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA | 著者 | Pandey, P, Gourinath, S. | 登録日 | 2016-05-06 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
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8DJ6
| Sliding-clamp-ImuB peptide | 分子名称: | ACETATE ION, Beta sliding clamp, FORMIC ACID, ... | 著者 | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | 登録日 | 2022-06-30 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Interaction of sliding clamp with mycobacterial polymerases To Be Published
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4K3Q
| E. coli sliding clamp in complex with AcQLDAF | 分子名称: | (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-04-11 | 公開日 | 2013-05-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
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4K74
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4K3M
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4K3O
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4K3K
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4K3P
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4K3R
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4K3L
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4K3S
| E. coli sliding clamp in P1 crystal space group | 分子名称: | CALCIUM ION, DNA polymerase III subunit beta, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-04-11 | 公開日 | 2013-05-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
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4MJR
| E. coli sliding clamp in complex with (S)-Carprofen | 分子名称: | (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-09-04 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
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4MJP
| E. coli sliding clamp in complex with (R)-Vedaprofen | 分子名称: | (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-09-04 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.855 Å) | 主引用文献 | DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
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4MJQ
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4N96
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4N95
| E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione | 分子名称: | 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-10-19 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
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4N94
| E. coli sliding clamp in complex with 3,4-difluorobenzamide | 分子名称: | 1,2-ETHANEDIOL, 3,4-difluorobenzamide, CALCIUM ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-10-19 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
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