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4N95

E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione

Summary for 4N95
Entry DOI10.2210/pdb4n95/pdb
Related4N94 4N96 4N97 4N98 4N99 4N9A
DescriptorDNA polymerase III subunit beta, TETRAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ... (8 entities in total)
Functional Keywordssliding clamp, dnan, transferase
Biological sourceEscherichia coli
Cellular locationCytoplasm: P0A988
Total number of polymer chains2
Total formula weight82707.58
Authors
Yin, Z.,Oakley, A.J. (deposition date: 2013-10-19, release date: 2013-11-06, Last modification date: 2023-09-20)
Primary citationYin, Z.,Whittell, L.R.,Wang, Y.,Jergic, S.,Liu, M.,Harry, E.J.,Dixon, N.E.,Beck, J.L.,Kelso, M.J.,Oakley, A.J.
Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach.
J.Med.Chem., 57:2799-2806, 2014
Cited by
PubMed: 24592885
DOI: 10.1021/jm500122r
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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