PDB: 158 件ウェブページステータス検索Chemie searchBIRD

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2O2M	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-30 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O22	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: Apoptosis regulator Bcl-2, N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O1Y	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O2N	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 4-[4-(BIPHENYL-2-YLMETHYL)PIPERAZIN-1-YL]-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-30 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O2F	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-2 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O21	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2P1L	Structure of the Bcl-XL:Beclin 1 complex 分子名称: Apoptosis regulator Bcl-X, Beclin 1 著者 Jeffrey, P.D, Shi, Y, Oberstein, A.L. 登録日 2007-03-05 公開日 2007-03-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein J.Biol.Chem., 282, 2007
2PON	Solution structure of the Bcl-xL/Beclin-1 complex 分子名称: Apoptosis regulator Bcl-X, Beclin-1 著者 Feng, W, Huang, S, Wu, H, Zhang, M. 登録日 2007-04-27 公開日 2007-09-04 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1. J.Mol.Biol., 372, 2007

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