PDB: 125 件ウェブページステータス検索Chemie searchBIRD

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2IMG	Crystal structure of dual specificity protein phosphatase 23 from Homo sapiens in complex with ligand malate ion 分子名称: D-MALATE, Dual specificity protein phosphatase 23 著者 Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2006-10-04 公開日 2006-10-17 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex. J.Biol.Chem., 283, 2008
2J16	Apo & Sulphate bound forms of SDP-1 分子名称: MAGNESIUM ION, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE YIL113W 著者 Briggs, D.C, McDonald, N.Q. 登録日 2006-08-09 公開日 2007-05-22 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases. Nature, 447, 2007
6L1S	Crystal structure of DUSP22 mutant_C88S 分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION 著者 Lai, C.H, Chang, C.C, Lyu, P.C. 登録日 2019-09-30 公開日 2020-10-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3611 Å) 主引用文献 Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
2J17	pTyr bound form of SDP-1 分子名称: MAGNESIUM ION, O-PHOSPHOTYROSINE, TYROSINE-PROTEIN PHOSPHATASE YIL113W 著者 Briggs, D.C, McDonald, N.Q. 登録日 2006-08-09 公開日 2007-05-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases. Nature, 447, 2007
6LMY	Crystal structure of DUSP22 mutant_C88S/S93A 分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION 著者 Lai, C.H, Lyu, P.C. 登録日 2019-12-27 公開日 2020-10-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
6LOT	Crystal structure of DUSP22 mutant_N128D 分子名称: Dual specificity protein phosphatase 22, SULFATE ION 著者 Lai, C.H, Lyu, P.C. 登録日 2020-01-07 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
6LVQ	Crystal structure of DUSP22_VO4 分子名称: Dual specificity protein phosphatase 22, VANADATE ION 著者 Lai, C.H, Lyu, P.C. 登録日 2020-02-04 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
6LOU	Crystal structure of DUSP22 mutant_C88S/S93N 分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION 著者 Lai, C.H, Lyu, P.C. 登録日 2020-01-07 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5301 Å) 主引用文献 Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
6MC1	Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-(methylthio)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, ACETATE ION, ... 著者 Gannam, Z.T.K, Anderson, K.S, Bennett, A.M, Lolis, E. 登録日 2018-08-30 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Sci.Signal., 13, 2020
5XJV	Two intermediate states of conformation switch in dual specificity phosphatase 13a 分子名称: Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION 著者 Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. 登録日 2017-05-04 公開日 2018-04-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Two intermediate states of the conformational switch in dual specificity phosphatase 13a Pharmacol. Res., 128, 2018
5Y15	Crystal structure of human DUSP28 分子名称: Dual specificity phosphatase 28, PHOSPHATE ION 著者 Ku, B, Hong, W, Kim, S.J, Ryu, S.E. 登録日 2017-07-19 公開日 2017-11-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
5Y16	Crystal structure of human DUSP28(Y102H) 分子名称: CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION 著者 Ku, B, Kim, M, Kim, S.J, Ryu, S.E. 登録日 2017-07-19 公開日 2017-11-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
5Z59	Crystal structure of Tk-PTP in the inactive form 分子名称: Protein-tyrosine phosphatase 著者 Ku, B, Yun, H.Y, Kim, S.J. 登録日 2018-01-17 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.703 Å) 主引用文献 Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
5Z5B	Crystal structure of Tk-PTP in the G95A mutant form 分子名称: CHLORIDE ION, FORMIC ACID, Protein-tyrosine phosphatase 著者 Ku, B, Yun, H.Y, Kim, S.J. 登録日 2018-01-17 公開日 2018-06-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
5Z5A	Crystal structure of Tk-PTP in the active form 分子名称: Protein-tyrosine phosphatase, VANADATE ION 著者 Ku, B, Yun, H.Y, Kim, S.J. 登録日 2018-01-17 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1 PLoS ONE, 13, 2018
3NME	Structure of a plant phosphatase 分子名称: PHOSPHATE ION, SEX4 glucan phosphatase 著者 Vander Kooi, C.W. 登録日 2010-06-22 公開日 2010-08-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the glucan phosphatase activity of Starch Excess4. Proc.Natl.Acad.Sci.USA, 107, 2010
4PYH	Phospho-glucan bound structure of starch phosphatase Starch EXcess4 reveals the mechanism for C6-specificty 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Meekins, D.A, Vander Kooi, C.W. 登録日 2014-03-27 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Phosphoglucan-bound structure of starch phosphatase Starch Excess4 reveals the mechanism for C6 specificity. Proc.Natl.Acad.Sci.USA, 111, 2014
1OHC	Structure of the proline directed phosphatase cdc14 分子名称: CDC14B2 PHOSPHATASE 著者 Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. 登録日 2003-05-24 公開日 2003-07-24 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase Embo J., 22, 2003
1OHE	Structure of cdc14b phosphatase with a peptide ligand 分子名称: CDC14B2 PHOSPHATASE, PEPTIDE LIGAND 著者 Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. 登録日 2003-05-24 公開日 2003-07-24 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase Embo J., 22, 2003
1OHD	structure of cdc14 in complex with tungstate 分子名称: CDC14B2 PHOSPHATASE, TUNGSTATE(VI)ION 著者 Gray, C.H, Good, V.M, Tonks, N.K, Barford, D. 登録日 2003-05-24 公開日 2003-07-24 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase Embo J., 22, 2003
6D65	Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein off7 分子名称: Designed AR protein off7, ETHANOL, GLYCEROL, ... 著者 Gumpena, R, Lountos, G.T, Waugh, D.S. 登録日 2018-04-20 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.348 Å) 主引用文献 MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
6D66	Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16 分子名称: 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ... 著者 Gumpena, R, Waugh, D.S, Lountos, G.T. 登録日 2018-04-20 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.226 Å) 主引用文献 MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
6D67	Crystal structure of the human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion (maltose bound form) in complex with the designed AR protein mbp3_16 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Designed AR protein mbp3_16, ... 著者 Gumpena, R, Lountos, G.T, Waugh, D.S. 登録日 2018-04-20 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
6G84	Structure of Cdc14 bound to CBK1 PxL motif 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CBK1, ... 著者 Mouilleron, S, Kataria, M, Uhlmann, F. 登録日 2018-04-07 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
6G86	Structure of Cdc14 bound to SIC1 PxL motif 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ... 著者 Mouilleron, S, Kataria, M, Uhlmann, F. 登録日 2018-04-07 公開日 2018-10-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018

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