PDB: 141 resultsInfo pagesStatus searchChemie searchBIRD

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2DFK	Crystal structure of the CDC42-Collybistin II complex Descriptor: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ... Authors: Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H. Deposit date: 2006-03-02 Release date: 2006-05-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor. J.Mol.Biol., 359, 2006
1XDV	Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang. Descriptor: Son of sevenless protein homolog 1 Authors: Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. Deposit date: 2004-09-08 Release date: 2004-11-02 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
1XD4	Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS) Descriptor: Son of sevenless protein homolog 1 Authors: Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. Deposit date: 2004-09-03 Release date: 2004-11-02 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.64 Å) Cite: Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
1XCG	Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA Authors: Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S. Deposit date: 2004-09-01 Release date: 2004-12-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle Structure, 12, 2004
1X86	Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA Descriptor: PHOSPHATE ION, Rho guanine nucleotide exchange factor 12, Transforming protein RhoA Authors: Kristelly, R, Gao, G, Tesmer, J.J. Deposit date: 2004-08-17 Release date: 2004-09-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor. J.Biol.Chem., 279, 2004
1TXD	Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF Descriptor: Rho guanine nucleotide exchange factor 12 Authors: Kristelly, R, Gao, G, Tesmer, J.J. Deposit date: 2004-07-03 Release date: 2004-09-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor. J.Biol.Chem., 279, 2004
1RJ2	Crystal structure of the DH/PH fragment of Dbs without bound GTPase Descriptor: Guanine nucleotide exchange factor DBS [Fragment] Authors: Worthylake, D.K, Rossman, K.L, Sondek, J. Deposit date: 2003-11-18 Release date: 2004-06-29 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the DH/PH fragment of Dbs without bound GTPase. Structure, 12, 2004
1NTY	Crystal structure of the first DH/PH domain of Trio to 1.7 A Descriptor: Triple functional domain protein Authors: Skowronek, K.R, Zheng, Y, Nassar, N. Deposit date: 2003-01-30 Release date: 2004-06-29 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids. J.Biol.Chem., 279, 2004
1LB1	Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA Descriptor: Guanine nucleotide exchange factor DBS, Transforming protein RhoA Authors: Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. Deposit date: 2002-04-01 Release date: 2002-05-29 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
1KZG	DbsCdc42(Y889F) Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS Authors: Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. Deposit date: 2002-02-06 Release date: 2002-03-20 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
1KZ7	Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42 Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS Authors: Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. Deposit date: 2002-02-06 Release date: 2002-03-20 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
1KI1	Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42 Descriptor: G25K GTP-binding protein, placental isoform, SULFATE ION, ... Authors: Snyder, J.T, Pruitt, W.M, Der, C.J, Sondek, J. Deposit date: 2001-12-02 Release date: 2002-05-29 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
1FOE	CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1 Descriptor: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1 Authors: Worthylake, D.K, Rossman, K.L, Sondek, J. Deposit date: 2000-08-27 Release date: 2001-01-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. Nature, 408, 2000
1F5X	NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLOGY DOMAIN Descriptor: RHO-GEF VAV Authors: Aghazadeh, B, Rosen, M.K, Lowry, W.E, Huang, X.Y. Deposit date: 2000-06-18 Release date: 2000-09-15 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation. Cell(Cambridge,Mass.), 102, 2000
1DBH	DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1 Descriptor: PROTEIN (HUMAN SOS 1) Authors: Soisson, S.M, Kuriyan, J. Deposit date: 1998-12-17 Release date: 1998-12-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein. Cell(Cambridge,Mass.), 95, 1998
1BY1	DBL homology domain from beta-PIX Descriptor: PROTEIN (PIX) Authors: Aghazadeh, B, Zhu, K, Kubiseski, T.J, Liu, G.A, Pawson, T, Zheng, Y, Rosen, M.K. Deposit date: 1998-10-22 Release date: 1999-10-24 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structure and Mutagenesis of the Dbl Homology Domain Nat.Struct.Biol., 5, 1998

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