1KZ7
Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
Summary for 1KZ7
Entry DOI | 10.2210/pdb1kz7/pdb |
Related | 1FOE 1KZG |
Descriptor | GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS, CDC42 HOMOLOG (3 entities in total) |
Functional Keywords | guanine nucleotide exchange factor (gef), small g-protein, signaling protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cytoplasm: Q64096 Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953 |
Total number of polymer chains | 4 |
Total formula weight | 125304.42 |
Authors | Rossman, K.L.,Worthylake, D.K.,Snyder, J.T.,Siderovski, D.P.,Campbell, S.L.,Sondek, J. (deposition date: 2002-02-06, release date: 2002-03-20, Last modification date: 2021-10-27) |
Primary citation | Rossman, K.L.,Worthylake, D.K.,Snyder, J.T.,Siderovski, D.P.,Campbell, S.L.,Sondek, J. A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21:1315-1326, 2002 Cited by PubMed: 11889037DOI: 10.1093/emboj/21.6.1315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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