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1FOE

CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1

Summary for 1FOE
Entry DOI10.2210/pdb1foe/pdb
NMR InformationBMRB: 5511
DescriptorT-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, ... (4 entities in total)
Functional Keywordsdbl homology domain, pleckstrin homology domain, gtpase, guanine nucleotide exchange factor, signaling protein, immune system-signaling protein complex, immune system/signaling protein
Biological sourceMus musculus (house mouse)
More
Cellular locationCell junction (By similarity): Q60610
Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000
Total number of polymer chains8
Total formula weight254537.46
Authors
Worthylake, D.K.,Rossman, K.L.,Sondek, J. (deposition date: 2000-08-27, release date: 2001-01-17, Last modification date: 2011-07-13)
Primary citationWorthylake, D.K.,Rossman, K.L.,Sondek, J.
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Nature, 408:682-688, 2000
Cited by
PubMed: 11130063
DOI: 10.1038/35047014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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