1KI1
Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42
Summary for 1KI1
| Entry DOI | 10.2210/pdb1ki1/pdb |
| Descriptor | G25K GTP-binding protein, placental isoform, intersectin long form, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | protein-protein complex, dh domain, ph domain, rho gtpase, signaling protein |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953 Endomembrane system (By similarity): Q15811 |
| Total number of polymer chains | 4 |
| Total formula weight | 123949.31 |
| Authors | Snyder, J.T.,Pruitt, W.M.,Der, C.J.,Sondek, J. (deposition date: 2001-12-02, release date: 2002-05-29, Last modification date: 2024-02-14) |
| Primary citation | Snyder, J.T.,Worthylake, D.K.,Rossman, K.L.,Betts, L.,Pruitt, W.M.,Siderovski, D.P.,Der, C.J.,Sondek, J. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9:468-475, 2002 Cited by PubMed: 12006984DOI: 10.1038/nsb796 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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