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4JOR
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BU of 4jor by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to HPV18 E6 oncoprotein C-terminal peptide (RLQRRRETQV)
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, Protein E6
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-03-18
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4JOK
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BU of 4jok by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide Y-iCAL36 (ANSRYPTSII)
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, Y-iCAL36 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-03-18
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4JOG
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BU of 4jog by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide V-iCAL36 (ANSRVPTSII)
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, V-iCAL36 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-03-18
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.465 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4JOJ
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BU of 4joj by Molmil
CFTR Associated Ligand (CAL) domain bound to peptide F-iCAL36 (ANSRFPTSII)
Descriptor: F-iCAL36 peptide, GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-03-18
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4JOP
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BU of 4jop by Molmil
CFTR Associated Ligand (CAL) PDZ bound to HPV16 E6 oncoprotein C-terminal peptide (TRRETQL)
Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, Protein E6
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-03-18
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4JL7
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BU of 4jl7 by Molmil
Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1
Descriptor: CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Lu, G, Wu, Y, Jiang, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z.
Deposit date:2013-03-12
Release date:2013-10-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1.
Plos One, 8, 2013
2M3M
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BU of 2m3m by Molmil
Solution structure of a complex consisting of hDlg/SAP-97 residues 318-406 and HPV51 oncoprotein E6 residues 141-151
Descriptor: Disks large homolog 1, Protein E6
Authors:Mischo, A, Ohlenschlager, O, Gorlach, M.
Deposit date:2013-01-22
Release date:2013-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain.
Plos One, 8, 2013
2M10
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BU of 2m10 by Molmil
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13
Authors:Walser, R.
Deposit date:2012-11-09
Release date:2013-07-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M0Z
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BU of 2m0z by Molmil
cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13
Authors:Walser, R, Zerbe, O, Hamm, P.
Deposit date:2012-11-09
Release date:2013-07-03
Last modified:2013-08-07
Method:SOLUTION NMR
Cite:Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M0T
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BU of 2m0t by Molmil
Structural characterization of the extended PDZ1 domain from NHERF1
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0U
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BU of 2m0u by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1
Descriptor: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0V
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BU of 2m0v by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1
Descriptor: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
4HOP
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BU of 4hop by Molmil
Crystal structure of the computationally designed NNOS-Syntrophin complex
Descriptor: Alpha-1-syntrophin, Nitric oxide synthase, brain
Authors:Harwood, I.M, Melero, C, Ollikainen, N, Kortemme, T.
Deposit date:2012-10-22
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
4H11
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BU of 4h11 by Molmil
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescent polarization spectroscopy
Descriptor: ACETATE ION, Disks large homolog 2, SULFATE ION
Authors:Fiorentini, M, Kastrup, J.S, Gajhede, M.
Deposit date:2012-09-10
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy.
Acta Crystallogr.,Sect.D, 69, 2013
4GVC
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BU of 4gvc by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with phosphorylated Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
4GVD
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BU of 4gvd by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide
Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), CHLORIDE ION, SODIUM ION, ...
Authors:Liu, X, Shepherd, T.R, Murray, A.M, Xu, Z, Fuentes, E.J.
Deposit date:2012-08-30
Release date:2013-03-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21, 2013
4G69
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BU of 4g69 by Molmil
Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex
Descriptor: Adenomatous polyposis coli protein, Disks large homolog 1
Authors:Slep, K.C.
Deposit date:2012-07-18
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Human Discs Large 1 PDZ2- Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering.
Plos One, 7, 2012
2LUI
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BU of 2lui by Molmil
Structure of the PICK PDZ domain in complex with the DAT C-terminal
Descriptor: PICK1 PDZ DOMAIN FUSED TO THE C10 DAT LIGAND
Authors:Erlendsson, S, Rathje, M, Heidarsson, P.O, Poulsen, F.M, Madsen, K.L, Teilum, K, Gether, U.
Deposit date:2012-06-14
Release date:2013-06-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.
J.Biol.Chem., 289, 2014
4F8K
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BU of 4f8k by Molmil
Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor
Authors:Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P.
Deposit date:2012-05-17
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1.
Plos One, 8, 2013
3VQG
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BU of 3vqg by Molmil
Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
Descriptor: C-terminal peptide from Immunoglobulin superfamily member 5, E3 ubiquitin-protein ligase LNX, SULFATE ION
Authors:Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H.
Deposit date:2012-03-23
Release date:2013-03-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
3VQF
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BU of 3vqf by Molmil
Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
Descriptor: E3 ubiquitin-protein ligase LNX
Authors:Akiyoshi, Y, Hamada, D, Goda, N, Tenno, T, Narita, H, Nakagawa, A, Furuse, M, Suzuki, M, Hiroaki, H.
Deposit date:2012-03-22
Release date:2013-03-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published
4AMH
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BU of 4amh by Molmil
Influence of circular permutation on the folding pathway of a PDZ domain
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DISKS LARGE HOMOLOG 1, GLYCEROL
Authors:Hultqvist, G, Punekar, A.S, Chi, C.N, Selmer, M, Gianni, S, Jemth, P.
Deposit date:2012-03-10
Release date:2012-12-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tolerance of Protein Folding to a Circular Permutation in a Pdz Domain
Plos One, 7, 2012
4E35
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BU of 4e35 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
4E34
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BU of 4e34 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ...
Authors:Amacher, J.F, Beck, T, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
4E3B
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BU of 4e3b by Molmil
Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: Tax1-binding protein 3, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013

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