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3VQG

Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein

Summary for 3VQG
Entry DOI10.2210/pdb3vqg/pdb
Related3VQF
DescriptorE3 ubiquitin-protein ligase LNX, C-terminal peptide from Immunoglobulin superfamily member 5, SULFATE ION, ... (4 entities in total)
Functional Keywordspdz domain, peptide binding, jam4 (junctional adhesion molecule-4) c-terminal peptide, cytoplasm(lnx1), membrane(jam4), peptide binding protein
Biological sourceMus musculus (mouse)
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Cellular locationCytoplasm: O70263
Cell membrane; Single-pass type I membrane protein: Q7TSN7
Total number of polymer chains2
Total formula weight11575.93
Authors
Akiyoshi, Y.,Hamada, D.,Goda, N.,Tenno, T.,Narita, H.,Nakagawa, A.,Furuse, M.,Suzuki, M.,Hiroaki, H. (deposition date: 2012-03-23, release date: 2013-03-27, Last modification date: 2023-11-08)
Primary citationAkiyoshi, Y.,Nakakura, Y.,Hamada, D.,Goda, N.,Tenno, T.,Narita, H.,Nakagawa, A.,Furuse, M.,Suzuki, M.,Hiroaki, H.
Structural basis for down regulation of tight junction by PDZ-domain containing E3-Ubiquitin ligase
To be Published,
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation

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