4GVD
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide
Summary for 4GVD
Entry DOI | 10.2210/pdb4gvd/pdb |
Related | 3KZD 3KZE 4GVC |
Descriptor | T-lymphoma invasion and metastasis-inducing protein 1, Syndecan-1, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | conformational change during phosphorylation, different binding pocket from phosphorylated sydencan1, scaffold signaling protein for cell adhesion and cell junction, sydencan1 n-terminal thr dansylation, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell junction: Q13009 Membrane; Single-pass type I membrane protein: P18827 |
Total number of polymer chains | 4 |
Total formula weight | 22995.99 |
Authors | Liu, X.,Shepherd, T.R.,Murray, A.M.,Xu, Z.,Fuentes, E.J. (deposition date: 2012-08-30, release date: 2013-03-13, Last modification date: 2023-09-13) |
Primary citation | Liu, X.,Shepherd, T.R.,Murray, A.M.,Xu, Z.,Fuentes, E.J. The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics. Structure, 21:342-354, 2013 Cited by PubMed: 23395182DOI: 10.1016/j.str.2013.01.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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