5ZRY
| Crystal Structure of EphA6/Odin Complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ... | Authors: | Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M. | Deposit date: | 2018-04-25 | Release date: | 2018-05-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. Elife, 7, 2018
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4NL9
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1PK3
| Scm SAM domain | Descriptor: | BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA | Authors: | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | Deposit date: | 2003-06-04 | Release date: | 2005-02-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J.Biol.Chem., 280, 2005
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8ATJ
| Crystal Structure of Shank2-SAM domain | Descriptor: | CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-08-23 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.117 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
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8B10
| Crystal Structure of Shank2-SAM mutant domain - L1800W | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-09-08 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
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4NJ8
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6LUK
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6LUJ
| Crystal structure of the SAMD1 SAM domain | Descriptor: | Atherin, SULFATE ION | Authors: | Cao, Y, Zhou, Y, Wang, Z. | Deposit date: | 2020-01-29 | Release date: | 2021-02-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
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4PZO
| Crystal structure of PHC3 SAM L967R | Descriptor: | Polyhomeotic-like protein 3 | Authors: | Nanyes, D.R, Junco, S.E, Taylor, A.B, Robinson, A.K, Patterson, N.L, Shivarajpur, A, Halloran, J, Hale, S.M, Kaur, Y, Hart, P.J, Kim, C.A. | Deposit date: | 2014-03-31 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motif. Proteins, 82, 2014
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4PZN
| Crystal structure of PHC3 SAM L971E | Descriptor: | 1,2-ETHANEDIOL, Polyhomeotic-like protein 3 | Authors: | Nanyes, D.R, Junco, S.E, Taylor, A.B, Robinson, A.K, Patterson, N.L, Shivarajpur, A, Halloran, J, Hale, S.M, Kaur, Y, Hart, P.J, Kim, C.A. | Deposit date: | 2014-03-31 | Release date: | 2014-07-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motif. Proteins, 82, 2014
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1SGG
| THE SOLUTION STRUCTURE OF SAM DOMAIN FROM THE RECEPTOR TYROSINE KINASE EPHB2, NMR, 10 STRUCTURES | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | Authors: | Smalla, M, Schmieder, P, Kelly, M, Ter Laak, A, Krause, G, Ball, L, Wahl, M, Bork, P, Oschkinat, H. | Deposit date: | 1999-01-08 | Release date: | 1999-10-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites. Protein Sci., 8, 1999
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2K4P
| Solution Structure of Ship2-Sam | Descriptor: | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | Authors: | Leone, M, Pellecchia, M. | Deposit date: | 2008-06-16 | Release date: | 2008-11-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor. Biochemistry, 47, 2008
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2KSO
| EphA2:SHIP2 SAM:SAM complex | Descriptor: | Ephrin type-A receptor 2, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 | Authors: | Hota, P.K, Preeti, C, Stetzik, L, Kim, S, Wang, B, Lee, H, Buck, M. | Deposit date: | 2010-01-10 | Release date: | 2011-07-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and function of the EphA2:SHIP2 SAM domain heterodimer To be Published
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2KE7
| NMR structure of the first SAM domain from AIDA1 | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B | Authors: | Donaldson, L. | Deposit date: | 2009-01-27 | Release date: | 2010-02-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the first SAM domain from AIDA1 To be Published
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2KIV
| AIDA-1 SAM domain tandem | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B | Authors: | Donaldson, L.W, Kurabi, A. | Deposit date: | 2009-05-12 | Release date: | 2009-08-25 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import. J.Mol.Biol., 392, 2009
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2LMR
| Solution structure of the first sam domain of odin | Descriptor: | Ankyrin repeat and SAM domain-containing protein 1A | Authors: | Leone, M, Mercurio, F. | Deposit date: | 2011-12-12 | Release date: | 2012-03-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor. Biochemistry, 51, 2012
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2EAN
| Solution structure of the N-terminal SAM-domain of human KIAA0902 protein (connector enhancer of kinase suppressor of ras 2) | Descriptor: | Connector enhancer of kinase suppressor of ras 2 | Authors: | Goroncy, A.K, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-31 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal SAM-domain of human KIAA0902 protein (connector enhancer of kinase suppressor of ras 2) To be Published
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2E8N
| Solution structure of the C-terminal SAM-domain of EphaA2: Ephrin type-A receptor 2 precursor (EC 2.7.10.1) | Descriptor: | Ephrin type-A receptor 2 | Authors: | Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-22 | Release date: | 2008-01-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal SAM-domain of EphaA2: Ephrin type-A receptor 2 precursor (EC 2.7.10.1) To be Published
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2EAM
| Solution structure of the N-terminal SAM-domain of a human putative 47 kDa protein | Descriptor: | Putative 47 kDa protein | Authors: | Goroncy, A.K, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-31 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal SAM-domain of a human putative 47 kDa protein To be Published
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2EAO
| Solution structure of the C-terminal SAM-domain of mouse ephrin type-B receptor 1 precursor (EC 2.7.1.112) | Descriptor: | Ephrin type-B receptor 1 | Authors: | Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-31 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal SAM-domain of mouse ephrin type-B receptor 1 precursor (EC 2.7.1.112) To be Published
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2F3N
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2F44
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3BS5
| Crystal Structure of hCNK2-SAM/dHYP-SAM Complex | Descriptor: | Connector enhancer of kinase suppressor of ras 2, Protein aveugle | Authors: | Rajakulendran, T, Ceccarelli, D.F, Kurinov, I, Sicheri, F. | Deposit date: | 2007-12-22 | Release date: | 2008-02-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc.Natl.Acad.Sci.USA, 105, 2008
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8P2M
| C. elegans TIR-1 protein. | Descriptor: | NAD(+) hydrolase tir-1 | Authors: | Isupov, M.N, Opatowsky, Y. | Deposit date: | 2023-05-16 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans. Cell Rep, 42, 2023
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5F3X
| Crystal structure of Harmonin NPDZ1 in complex with ANKS4B SAM-PBM | Descriptor: | Ankyrin repeat and SAM domain-containing protein 4B, CHLORIDE ION, Harmonin | Authors: | Li, J, He, Y, Lu, Q, Zhang, M. | Deposit date: | 2015-12-03 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.649 Å) | Cite: | Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex Dev.Cell, 36, 2016
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