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2K4P

Solution Structure of Ship2-Sam

Summary for 2K4P
Entry DOI10.2210/pdb2k4p/pdb
DescriptorPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 (1 entity in total)
Functional Keywordshelix bundle, signaling protein, actin-binding, alternative splicing, cell adhesion, cytoplasm, cytoskeleton, diabetes mellitus, hydrolase, immune response, membrane, phosphoprotein, polymorphism, sh2 domain, sh3-binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytosol: O15357
Total number of polymer chains1
Total formula weight9548.54
Authors
Leone, M.,Pellecchia, M. (deposition date: 2008-06-16, release date: 2008-11-25, Last modification date: 2022-03-16)
Primary citationLeone, M.,Cellitti, J.,Pellecchia, M.
NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor.
Biochemistry, 47:12721-12728, 2008
Cited by
PubMed: 18991394
DOI: 10.1021/bi801713f
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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