3BS5

Crystal Structure of hCNK2-SAM/dHYP-SAM Complex

Summary for 3BS5

Entry DOI	10.2210/pdb3bs5/pdb
Related	3BS7
Descriptor	Protein aveugle, Connector enhancer of kinase suppressor of ras 2 (3 entities in total)
Functional Keywords	sterile alpha motif, sam domain, sam domain dimer, sam domain complex, cytoplasm, membrane, sensory transduction, vision, alternative splicing, coiled coil, phosphoprotein, polymorphism, signaling protein-membrane protein complex, signaling protein/membrane protein
Biological source	Drosophila melanogaster (fruit fly) More
Cellular location	Cytoplasm: Q8ML92 Q8WXI2
Total number of polymer chains	2
Total formula weight	22324.39
Authors	Rajakulendran, T.,Ceccarelli, D.F.,Kurinov, I.,Sicheri, F. (deposition date: 2007-12-22, release date: 2008-02-26, Last modification date: 2011-07-13)
Primary citation	Rajakulendran, T.,Sahmi, M.,Kurinov, I.,Tyers, M.,Therrien, M.,Sicheri, F. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proc.Natl.Acad.Sci.USA, 105:2836-2841, 2008 Cited by PubMed: 18287031 DOI: 10.1073/pnas.0709705105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation