PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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7ZH3	USP1 bound to ubiquitin conjugated to FANCD2 (focused refinement) 分子名称: Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ZINC ION 著者 Rennie, M.L, Walden, H. 登録日 2022-04-05 公開日 2022-10-12 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
8A9J	Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323 (consensus reconstruction) 分子名称: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... 著者 Rennie, M.L, Walden, H. 登録日 2022-06-28 公開日 2022-10-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
8A9K	Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 with ML323 (consensus reconstruction) 分子名称: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, DNA (61-MER), Fanconi anemia group D2 protein, ... 著者 Rennie, M.L, Walden, H. 登録日 2022-06-28 公開日 2022-10-12 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
5L8W	Structure of USP12-UB-PRG/UAF1 分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ... 著者 Dharadhar, S, Sixma, T. 登録日 2016-06-08 公開日 2016-09-28 最終更新日 2016-11-30 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
5KYC	Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin (malonate bound) 分子名称: GLYCEROL, MALONIC ACID, Polyubiquitin-B, ... 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.426 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5KYF	Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin 分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5KYE	Crystal structure of USP7 catalytic domain [H294E] mutant in complex with ubiquitin 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5L8H	Structure of USP46-UbVME 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION 著者 Clerici, M, Sixma, T, Dharadhar, S. 登録日 2016-06-07 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme. J.Struct.Biol., 196, 2016
5KYD	Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5MPC	26S proteasome in presence of BeFx (s4) 分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... 著者 Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. 登録日 2016-12-16 公開日 2017-03-08 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6HEK	Structure of human USP28 bound to Ubiquitin-PA 分子名称: CHLORIDE ION, Polyubiquitin-B, TETRAETHYLENE GLYCOL, ... 著者 Gersch, M, Komander, D. 登録日 2018-08-20 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity. Mol.Cell, 74, 2019
6HEI	Structure of the catalytic domain of USP28 (insertion deleted) bound to Ubiquitin-PA 分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28 著者 Gersch, M, Komander, D. 登録日 2018-08-20 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity. Mol.Cell, 74, 2019
6JLQ	Crystal structure of human USP46-WDR48-WDR20 complex 分子名称: GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ... 著者 Zhu, H, Zhang, T, Ding, J. 登録日 2019-03-06 公開日 2019-07-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Structural insights into the activation of USP46 by WDR48 and WDR20. Cell Discov, 5, 2019
6H4H	Usp28 catalytic domain variant E593D in complex with UbPA 分子名称: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 28, ... 著者 Klemm, T.A, Sauer, F, Kisker, C. 登録日 2018-07-21 公開日 2019-03-27 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Mol.Cell, 74, 2019
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3A	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3K	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3I	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-18 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3M	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-18 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022

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