5KYF

Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin

Summary for 5KYF

• Entry DOI: 10.2210/pdb5kyf/pdb
• Related: 5KYB 5KYC 5KYD 5KYE
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, Polyubiquitin-B, GLYCEROL, ... (4 entities in total)
• Functional Keywords: usp7 catalytic domain, deubiquitinase, l299a mutant, ubiquitin, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 49306.82

Authors

Rouge, L.,Ozen, A. (deposition date: 2016-07-21, release date: 2017-08-09, Last modification date: 2023-10-04)

• Primary citation: Ozen, A.,Rouge, L.,Bashore, C.,Hearn, B.R.,Skelton, N.J.,Dueber, E.C.; Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.; Structure, 26:72-84.e7, 2018; PubMed: 29249604; DOI: 10.1016/j.str.2017.11.010

Experimental method

X-RAY DIFFRACTION (1.45 Å)