PDB: 109 resultsInfo pagesStatus searchChemie searchBIRD

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4X3U	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with Suramin Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Chromobox protein homolog 7 Authors: Ren, C, Zhou, M.M. Deposit date: 2014-12-01 Release date: 2015-03-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4X3S	Crystal structure of chromobox homology 7 (CBX7) with SETDB1-1170me3 Peptide Descriptor: CITRIC ACID, Chromobox protein homolog 7, FE (III) ION, ... Authors: Ren, C, Plotnikov, A.N, Zhou, M.M. Deposit date: 2014-12-01 Release date: 2015-03-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4X3T	Crystal structure of chromobox homolog 7 (CBX7) chromodomain with MS37452 Descriptor: 1,2-ETHANEDIOL, 1-[4-(2,3-dimethoxybenzoyl)piperazin-1-yl]-2-(3-methylphenoxy)ethanone, Chromobox protein homolog 7, ... Authors: Ren, C, Jakoncic, J, Zhou, M.M. Deposit date: 2014-12-01 Release date: 2015-03-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4QUC	Crystal structure of chromodomain of Rhino Descriptor: RE36324p Authors: Li, S, Patel, D.J. Deposit date: 2014-07-10 Release date: 2014-08-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.502 Å) Cite: Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev., 28, 2014
4QUF	crystal structure of chromodomain of Rhino with H3K9me3 Descriptor: H3(1-15)K9me3 peptide, RE36324p Authors: Li, S, Patel, D.J. Deposit date: 2014-07-10 Release date: 2014-08-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev., 28, 2014
2M2L	Solution structure of Entamoeba histolytica HP1 chromodomain Descriptor: Putative uncharacterized protein Authors: Wiggins, K.R, Ren, X, Ali, I.K.M, Petri, W.A, Khorasanizadeh, S. Deposit date: 2012-12-28 Release date: 2014-05-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Characterization of putative readers of epigenetic methyl-marks from Entamoeba histolytica To be Published
2MJ8	Solution structure of CDYL2 chromodomain Descriptor: Chromodomain Y-like protein 2 Authors: Qin, S, Houliston, S, Arrowsmith, C.H, Edwards, A.M, Wu, H, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2013-12-28 Release date: 2014-04-23 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
4O42	Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 Descriptor: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... Authors: Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2013-12-18 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
4MN3	Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7) Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Chromobox protein homolog 7, ... Authors: Chakravarthi, S, Daze, K, Douglas, S, Quon, T, Dev, A, Peng, F, Heller, M, Boulanger, M.J, Wulff, J, Hof, F. Deposit date: 2013-09-09 Release date: 2014-04-02 Last modified: 2014-10-08 Method: X-RAY DIFFRACTION (1.542 Å) Cite: Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7). J.Med.Chem., 57, 2014
4NW2	Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229 Descriptor: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... Authors: Qin, S, Tempel, W, Xu, C, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2013-12-05 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4HAE	Crystal structure of the CDYL2-chromodomain Descriptor: Chromodomain Y-like protein 2, SULFATE ION, UNKNOWN ATOM OR ION Authors: Qin, S, Dombrovski, L, Tempel, W, Dong, A, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) Deposit date: 2012-09-26 Release date: 2012-10-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the CDYL2-chromodomain To be Published
2RSN	Solution structure of the chromodomain of Chp1 in complex with H3K9me3 peptide Descriptor: Chromo domain-containing protein 1, peptide from Histone H3 Authors: Shimojo, H, Nishimura, Y. Deposit date: 2012-04-18 Release date: 2012-08-29 Method: SOLUTION NMR Cite: Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing Mol.Cell, 47, 2012
2RSO	Solution structure of the chromodomain of Swi6 Descriptor: Chromatin-associated protein swi6 Authors: Shimojo, H, Nishimura, Y. Deposit date: 2012-04-18 Release date: 2012-08-29 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing Mol.Cell, 47, 2012
3TZD	Crystal structure of the complex of Human Chromobox Homolog 3 (CBX3) Descriptor: Chromobox protein homolog 3, Histone H1.4 Authors: Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) Deposit date: 2011-09-27 Release date: 2012-03-07 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a. Plos One, 7, 2012
3SVM	Human MPP8 - human DNMT3AK47me2 peptide Descriptor: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8 Authors: Chang, Y, Horton, J.R, Zhang, X, Cheng, X. Deposit date: 2011-07-12 Release date: 2011-11-30 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2, 2011
3QO2	Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9 Descriptor: 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8 Authors: Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X. Deposit date: 2011-02-09 Release date: 2011-04-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding. J.Mol.Biol., 408, 2011
3R93	Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide Descriptor: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION Authors: Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC) Deposit date: 2011-03-24 Release date: 2011-04-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.057 Å) Cite: Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9. Plos One, 6, 2011
3MWY	Crystal structure of the chromodomain-ATPase portion of the yeast Chd1 chromatin remodeler Descriptor: Chromo domain-containing protein 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Hauk, G, Bowman, G.D. Deposit date: 2010-05-06 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.7 Å) Cite: The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor. Mol.Cell, 39, 2010
2L1B	Solution NMR structure of the chromobox protein Cbx7 with H3K27me3 Descriptor: Chromobox protein homolog 7, Histone H3 Authors: Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Muhandiram, R, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) Deposit date: 2010-07-27 Release date: 2010-08-25 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
2L12	Solution NMR structure of the chromobox protein 7 with H3K9me3 Descriptor: Chromobox homolog 7, Histone H3 Authors: Kaustov, L, Lemak, A, Gutmanas, A, Fares, C, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) Deposit date: 2010-07-22 Release date: 2010-08-04 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
2L11	Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide Descriptor: Chromobox protein homolog 3, Histone H3 Authors: Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) Deposit date: 2010-07-22 Release date: 2010-08-04 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
2KVM	Solution structure of the CBX7 chromodomain in complex with a H3K27me2 peptide Descriptor: Chromobox protein homolog 7, histone H3 peptide (residues 15-30) with dimethylated lysine 27 Authors: Yap, K.L, Zeng, L, Zhou, M. Deposit date: 2010-03-17 Release date: 2010-06-30 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol.Cell, 38, 2010

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