3SVM

Human MPP8 - human DNMT3AK47me2 peptide

Summary for 3SVM

• Entry DOI: 10.2210/pdb3svm/pdb
• Related: 3QO2 3SW9 3SWC
• Descriptor: M-phase phosphoprotein 8, DNA (cytosine-5)-methyltransferase 3A (3 entities in total)
• Functional Keywords: epigenetics, methyl-lysine binding, chromodomain, the dimethylated human dnmt3ak47me2 is recognized by the chromodomain of mpp8, mpp8 chromodomain, dimethylated lysine, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q99549 Q9Y6K1
• Total number of polymer chains: 2
• Total formula weight: 9050.29

Authors

Chang, Y.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2011-07-12, release date: 2011-11-30, Last modification date: 2023-09-13)

• Primary citation: Chang, Y.,Sun, L.,Kokura, K.,Horton, J.R.,Fukuda, M.,Espejo, A.,Izumi, V.,Koomen, J.M.,Bedford, M.T.,Zhang, X.,Shinkai, Y.,Fang, J.,Cheng, X.; MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.; Nat Commun, 2:533-533, 2011; PubMed: 22086334; DOI: 10.1038/ncomms1549

Experimental method

X-RAY DIFFRACTION (2.31 Å)