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5N90
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BU of 5n90 by Molmil
Crystal Structure of Drosophila DHX36 helicase in complex with TTGTGGTGT
Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*TP*GP*TP*GP*GP*TP*GP*T)-3'), ...
Authors:Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G.
Deposit date:2017-02-24
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.069 Å)
Cite:Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model.
Structure, 26, 2018
5N8S
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BU of 5n8s by Molmil
Crystal Structure of Drosophila DHX36 helicase in complex with polyT
Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Chen, W.-F, Rety, S, Hai-Lei Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G.
Deposit date:2017-02-24
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model.
Structure, 26, 2018
5LTK
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BU of 5ltk by Molmil
Crystal structure of the Prp43-ADP-BeF3 complex (in hexagonal space group)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Tauchert, M.J, Ficner, R.
Deposit date:2016-09-06
Release date:2017-01-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.241 Å)
Cite:Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
5M5P
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BU of 5m5p by Molmil
S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8
Descriptor: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2
Authors:Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C.
Deposit date:2016-10-22
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
Cell Cycle, 16, 2017
6AC6
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BU of 6ac6 by Molmil
Ab initio crystal structure of Selenomethionine labelled Mycobacterium smegmatis Mfd
Descriptor: Mycobacterium smegmatis Mfd, SULFATE ION
Authors:Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R.
Deposit date:2018-07-25
Release date:2019-08-28
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
6ACA
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BU of 6aca by Molmil
Crystal structure of Mycobacterium tuberculosis Mfd at 3.6 A resolution
Descriptor: Mycobacterium tuberculosis Mfd
Authors:Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R.
Deposit date:2018-07-26
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
6AC8
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BU of 6ac8 by Molmil
Crystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolution
Descriptor: Mycobacterium smegmatis Mfd, SULFATE ION
Authors:Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R.
Deposit date:2018-07-25
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
6ACX
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BU of 6acx by Molmil
Crystal structure of Mycobacterium smegmatis Mfd in complex with ADP + Pi at 3.5 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mycobacterium smegmatis Mfd, PHOSPHATE ION, ...
Authors:Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R.
Deposit date:2018-07-27
Release date:2019-08-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
6B4K
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BU of 6b4k by Molmil
Crystal structure of human DDX19B(AMPPNP)
Descriptor: ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, MALONATE ION, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6BB8
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BU of 6bb8 by Molmil
Crystal Structure of Frequency-Interacting RNA helicase (FRH)
Descriptor: FRQ-interacting RNA helicase
Authors:Morales, Y, Johnson, S.J, Olsen, K.J.
Deposit date:2017-10-17
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of frequency-interacting RNA helicase from Neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveillance.
PLoS ONE, 13, 2018
6B4J
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BU of 6b4j by Molmil
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex
Descriptor: ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, Nucleoporin GLE1, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4I
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BU of 6b4i by Molmil
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nucleoporin GLE1, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.619 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6C90
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BU of 6c90 by Molmil
Human Mtr4 helicase in complex with ZCCHC8-CTD
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, L(+)-TARTARIC ACID, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2018-01-25
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CRM
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BU of 6crm by Molmil
Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex
Descriptor: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION
Authors:Voter, A.F, Keck, J.L.
Deposit date:2018-03-19
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.19286251 Å)
Cite:A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases.
Nat Commun, 9, 2018
6CZ5
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BU of 6cz5 by Molmil
Crystal structure of small molecule AMP-acrylamide covalently bound to DDX3 S228C
Descriptor: 5'-O-[(R)-hydroxy(propanoylamino)phosphoryl]adenosine, ATP-dependent RNA helicase DDX3X
Authors:Barkovich, K.J, Moore, M.K, Hu, Q, Shokat, K.M.
Deposit date:2018-04-08
Release date:2018-08-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chemical genetic inhibition of DEAD-box proteins using covalent complementarity.
Nucleic Acids Res., 46, 2018
8DVR
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BU of 8dvr by Molmil
Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+AMPPNP)
Descriptor: Antiviral innate immune response receptor RIG-I, GUANOSINE-5'-TRIPHOSPHATE, ZINC ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8DVS
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BU of 8dvs by Molmil
Cryo-EM structure of RIG-I bound to the end of OHSLR30 (+ATP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-16
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8DVU
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BU of 8dvu by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of OHSLR30 (+ATP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-07-29
Release date:2022-11-16
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
8EJM
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BU of 8ejm by Molmil
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DHX15, CHLORIDE ION, ...
Authors:Huang, J, Tong, L.
Deposit date:2022-09-17
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
6ZM2
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BU of 6zm2 by Molmil
Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA
Descriptor: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hamann, F, Ficner, R.
Deposit date:2020-07-01
Release date:2021-04-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases.
Acta Crystallogr D Struct Biol, 77, 2021
6ZWX
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BU of 6zwx by Molmil
Crystal structure of E. coli RNA helicase HrpA
Descriptor: ATP-dependent RNA helicase HrpA
Authors:Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
8ENK
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BU of 8enk by Molmil
Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Xie, Y, Ren, Y.
Deposit date:2022-09-30
Release date:2023-08-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly.
Cell Rep, 42, 2023
6ZWW
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BU of 6zww by Molmil
Crystal structure of E. coli RNA helicase HrpA in complex with RNA
Descriptor: ATP-dependent RNA helicase HrpA, CALCIUM ION, ssRNA
Authors:Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C.
Deposit date:2020-07-29
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A8R
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BU of 7a8r by Molmil
Structure of RecQL from Bos taurus
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, MAGNESIUM ION, ...
Authors:Rety, S, Chen, W.F, Xi, X.G.
Deposit date:2020-08-30
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers.
Cell Rep, 36, 2021
7AUD
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BU of 7aud by Molmil
Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ...
Authors:Chen, X, Oliver, A.W.
Deposit date:2020-11-02
Release date:2020-12-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein.
Elife, 10, 2021

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数据于2024-05-01公开中

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