6C90

Human Mtr4 helicase in complex with ZCCHC8-CTD

Summary for 6C90

• Entry DOI: 10.2210/pdb6c90/pdb
• Descriptor: Exosome RNA helicase MTR4,Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: hydrolase, next, exosome, nucleotide-binding, atpase, rna, helicase, translocase, rna binding protein, hydrolase-rna binding protein complex, hydrolase/rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 90110.50

Authors

Puno, M.R.,Lima, C.D. (deposition date: 2018-01-25, release date: 2018-05-30, Last modification date: 2023-10-04)

• Primary citation: Puno, M.R.,Lima, C.D.; Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.; Proc. Natl. Acad. Sci. U.S.A., 115:E5506-E5515, 2018; PubMed: 29844170; DOI: 10.1073/pnas.1803530115

Experimental method

X-RAY DIFFRACTION (2.2 Å)