PDB: 1416 resultsInfo pagesStatus searchChemie searchBIRD

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4B95	pVHL-EloB-EloB-EloC complex_(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound Descriptor: (2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... Authors: Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. Deposit date: 2012-08-31 Release date: 2012-10-24 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
4B9K	pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound Descriptor: (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... Authors: Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. Deposit date: 2012-09-05 Release date: 2012-10-24 Last modified: 2013-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
4BBN	NEDD4 HECT-Ub:Ub complex Descriptor: E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B Authors: Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. Deposit date: 2012-09-27 Release date: 2013-05-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
4BKS	von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide Descriptor: (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... Authors: Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. Deposit date: 2013-04-29 Release date: 2013-11-27 Last modified: 2014-01-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
4BKT	von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide Descriptor: (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ... Authors: Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. Deposit date: 2013-04-29 Release date: 2013-11-27 Last modified: 2017-07-12 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
4BOS	Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide Descriptor: MAGNESIUM ION, NITRATE ION, OTUD2, ... Authors: Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. Deposit date: 2013-05-22 Release date: 2013-07-24 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
4BOZ	Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin Descriptor: GLYCEROL, UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C Authors: Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. Deposit date: 2013-05-22 Release date: 2013-07-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
4BVU	Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate Descriptor: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3 Authors: Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S. Deposit date: 2013-06-28 Release date: 2014-01-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis. Embo J., 33, 2014
4D5L	Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state Descriptor: 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... Authors: Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. Deposit date: 2014-11-05 Release date: 2015-02-04 Last modified: 2017-08-23 Method: ELECTRON MICROSCOPY (9 Å) Cite: Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
4D61	Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... Authors: Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. Deposit date: 2014-11-07 Release date: 2015-03-04 Last modified: 2017-08-30 Method: ELECTRON MICROSCOPY (9 Å) Cite: Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
4DDG	Crystal structure of human OTUB1/UbcH5b~Ub/Ub Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1 Authors: Juang, Y.C, Sanches, M, Sicheri, F. Deposit date: 2012-01-18 Release date: 2012-02-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.2987 Å) Cite: OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Mol.Cell, 45, 2012
4DDI	Crystal structure of human OTUB1/UbcH5b~Ub/Ub Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1 Authors: Juang, Y.C, Sanches, M, Sicheri, F. Deposit date: 2012-01-18 Release date: 2012-02-22 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (3.802 Å) Cite: OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Mol.Cell, 45, 2012
4DHJ	The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex Descriptor: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... Authors: Wiener, R, Zhang, X, Wang, T, Wolberger, C. Deposit date: 2012-01-27 Release date: 2012-02-22 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.35 Å) Cite: The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
4DHZ	The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub Descriptor: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... Authors: Wiener, R, Zhang, X, Wang, T, Wolberger, C. Deposit date: 2012-01-30 Release date: 2012-02-22 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (3.11 Å) Cite: The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
4DWF	Crystal structure of a HLA-B associated transcript 3 (BAT3) from Homo sapiens at 1.80 A resolution Descriptor: HLA-B-associated transcript 3, SULFATE ION Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-02-24 Release date: 2012-03-28 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a HLA-B associated transcript 3 (BAT3) from Homo sapiens at 1.80 A resolution To be published
4EEW	Crystal structure of the Ubl domain of BAG6 Descriptor: Large proline-rich protein BAG6 Authors: Kozlov, G, LePage, K, Vinaik, R, Gehring, K. Deposit date: 2012-03-28 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of the Ubl domain of BAG6 To be Published
4F8C	Structure of the Cif:Nedd8 complex - Yersinia pseudotuberculosis Cycle Inhibiting Factor in complex with human Nedd8 Descriptor: 1,2-ETHANEDIOL, Cycle Inhibiting Factor, NEDD8 Authors: Crow, A, Banfield, M. Deposit date: 2012-05-17 Release date: 2012-06-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif Proc.Natl.Acad.Sci.USA, 2012
4FBJ	Structure of the Cif:Nedd8 complex - Photorhabdus luminescens Cycle Inhibiting Factor in complex with human Nedd8 Descriptor: CHLORIDE ION, Hypothetical protein, NEDD8 Authors: Crow, A, Banfield, M.J. Deposit date: 2012-05-23 Release date: 2012-06-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The molecular basis of Nedd8 deamidation by the bacterial effector protein Cif Proc.Natl.Acad.Sci.USA, 2012
4FJV	Crystal Structure of Human Otubain2 and Ubiquitin Complex Descriptor: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... Authors: Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. Deposit date: 2012-06-12 Release date: 2013-06-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.047 Å) Cite: The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages. Plos One, 10, 2015
4FN2	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ37 Descriptor: Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase, ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-06-19 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4G50	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ168 Descriptor: 1,2-ETHANEDIOL, 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, FORMIC ACID, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-07-17 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4GGQ	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with CJ40 Descriptor: 3-(3,4,5-trimethoxyphenyl)propyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-08-07 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4GIV	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G from Burkholderia pseudomallei complexed with CJ183 Descriptor: 3-(pyridin-3-yl)propyl (2S)-1-[(3-nitrophenyl)sulfonyl]piperidine-2-carboxylate, FORMIC ACID, Ubiquitin-like protein SMT3, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-08-09 Release date: 2012-09-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4GOC	Crystal structure of the Get5 ubiquitin-like domain Descriptor: Golgi to ER traffic protein 5 Authors: Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M. Deposit date: 2012-08-19 Release date: 2012-11-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface. Cell Rep, 2, 2012
4GSW	Crystal structure of ubiquitin from Entamoeba histolytica to 2.15 Angstrom Descriptor: SULFATE ION, Ubiquitin Authors: Bosch, D.E, Siderovski, D.P. Deposit date: 2012-08-28 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica. J.Biol.Chem., 288, 2013

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