4FJV

Crystal Structure of Human Otubain2 and Ubiquitin Complex

Summary for 4FJV

• Entry DOI: 10.2210/pdb4fjv/pdb
• Descriptor: Ubiquitin thioesterase OTUB2, Polyubiquitin-C, GLYCEROL, ... (5 entities in total)
• Functional Keywords: ubiquitin, otubain, nedd8, cleavage specificity, deubiquitylation, cysteine protease, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Ubiquitin: Cytoplasm : P0CG48
• Total number of polymer chains: 4
• Total formula weight: 75307.37

Authors

Altun, M.,Walter, T.S.,Kramer, H.B.,Iphofer, A.,David, Y.,Komsany, A.,Ternette, N.,Nicholson, B.,Navon, A.,Stuart, D.I.,Ren, J.,Kessler, B.M. (deposition date: 2012-06-12, release date: 2013-06-12, Last modification date: 2023-09-13)

• Primary citation: Altun, M.,Walter, T.S.,Kramer, H.B.,Herr, P.,Iphofer, A.,Bostrom, J.,David, Y.,Komsany, A.,Ternette, N.,Navon, A.,Stuart, D.I.,Ren, J.,Kessler, B.M.; The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.; Plos One, 10:e0115344-e0115344, 2015; PubMed: 25590432; DOI: 10.1371/journal.pone.0115344

Experimental method

X-RAY DIFFRACTION (2.047 Å)